An ABO-incompatible living donor liver transplant in an infant with acute liver failure in the Sri Lankan setting

IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Ceylon Medical Journal Pub Date : 2023-11-16 DOI:10.4038/cmj.v68i1.9714
Meranthi Fernando, S. Tillakaratne, B. Gunetilleke, Chamila Liyanage, C. Appuhamy, Aruna Weerasuriya, Janaki Dissanayake, Rohan Siriwardana
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Abstract

Liver transplant (LT) is the standard therapy for medically refractory acute liver failure (ALF). Finding a deceaseddonor graft in an emergency is challenging and often overcome by living-donation. Blood group matching is practised for LT though ABO-incompatible liver transplant (ABOi-LT) is performed inselected circumstances. We report an infant who underwent successful ABOincompatible living donor LT for ALF of unknown aetiology. This being the country’s first ABOi-LT, the youngest LT recipient to date and the youngest receiving emergency LT for ALF; we describe the novel experience at a resource-limited setting in Sri Lanka (SL).
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斯里兰卡一名急性肝功能衰竭婴儿的 ABO 不兼容活体肝移植手术
肝移植(LT)是治疗药物难治性急性肝衰竭(ALF)的标准疗法。在紧急情况下寻找供体具有挑战性,通常需要活体供体。虽然ABO血型不相容肝移植(ABOi-LT)是在特殊情况下进行的,但在LT中也实行血型匹配。我们报告了一名因病因不明的 ALF 而成功接受 ABO 不相容活体肝移植的婴儿。这是斯里兰卡的首例ABOi-LT,也是迄今为止年龄最小的LT受者和年龄最小的因ALF而接受紧急LT的受者。
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来源期刊
Ceylon Medical Journal
Ceylon Medical Journal MEDICINE, GENERAL & INTERNAL-
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期刊介绍: The Ceylon Medical Journal, is the oldest surviving medical journal in Australasia. It is the only medical journal in Sri Lanka that is listed in the Index Medicus. The CMJ started life way back in 1887 as the organ of the Ceylon Branch of the British Medical Association. Except for a brief period between 1893 and 1904 when it ceased publication, the CMJ or its forbear, the Journal of the Ceylon Branch of the British Medical Association, has been published without interruption up to now. The journal"s name changed to the CMJ in 1954.
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