Deformability Of Erythrocytes And Microcirculation In Old Patients With Hypoxia Of Various Genesis

Abstract

Age-related changes in the deformability of erythrocyte membranes against the background of heart and respiratory failure exacerbate disorders of the blood supply to tissues and organs at the microcirculatory level, which is an important factor in worsening the prognosis of the disease, especially in people over 60 years of age. The purpose of the work is to investigate the patterns of changes in the deformability of erythrocyte membranes against the background of heart and respiratory failure in older people. In older patients against the background of COPD and CHF, a decrease in the deformability of erythrocyte membranes and associated microcirculation disorders against the background of hypoxia are detected. Age-related physiological changes in the morpho-functional state of erythrocyte membranes and changes in the deformability of their membranes against the background of somatic pathology (heart, respiratory failure, fever) lead to a syndrome of mutual weighting, exacerbate disorders of the blood supply to tissues and organs at the microcirculatory level, which is an important factor in worsening the prognosis diseases, especially in people over 65 years of age.