Nanoparticles as illuminating allies: Advancing diagnostic frontiers in COVID-19- A review

THE SCIENTIFIC TEMPER Pub Date : 2023-07-18 DOI:10.58414/scientifictemper.2023.14.3.56

Naveen Kumar, Renu, Suresh Kumar Gahlawat, Anil Kumar, Vikram Delu, Pooja, Shekhar Anand, Suresh Chandra Singh, Arbind Acharya

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Abstract

Nanoparticles (NPs) have emerged as indispensable tools in the fight against the coronavirus disease (COVID-19) or severe acute respiratory syndrome coronavirus 2 (SARS-Cov2) pandemic, finding extensive utilization in both diagnosis and therapeutics. Their ability to interact with the virus and host cells in diverse manners positions them as valuable assets for detecting, treating, and preventing COVID-19. In this comprehensive review, a detailed summary of the state-of-the-art NP-based diagnostic methods for COVID-19 has been presented, particularly important classes of gold nanoparticles (GNPs), magnetic nanoparticles (MNPs), quantum dots, liposomes, silica nanoparticles (SNPs), silver nanoparticles (AgNPs), zinc oxide nanoparticles (ZnO-NPs), and carbon nanotubes (CNTs) delineating and their inherent strengths as well as limitations. Additionally, the challenges and opportunities that have been addressed lie ahead in pursuing future advancements and clinical translation of NP-based technologies for diagnosing COVID-19.

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纳米粒子作为照明盟友：推进 COVID-19 诊断前沿--综述

纳米粒子（NPs）已成为抗击冠状病毒病（COVID-19）或严重急性呼吸系统综合征冠状病毒 2（SARS-Cov2）大流行不可或缺的工具，在诊断和治疗中都得到了广泛应用。它们能以各种方式与病毒和宿主细胞相互作用，是检测、治疗和预防 COVID-19 的宝贵资产。本综述详细总结了最先进的基于纳米粒子的 COVID-19 诊断方法，特别是金纳米粒子 (GNPs)、磁性纳米粒子 (MNPs)、量子点、脂质体、二氧化硅纳米粒子 (SNPs)、银纳米粒子 (AgNPs)、氧化锌纳米粒子 (ZnO-NPs) 和碳纳米管 (CNTs) 等重要类别，并对它们的固有优势和局限性进行了描述。此外，在寻求基于 NP 的 COVID-19 诊断技术的未来发展和临床转化过程中，还面临着挑战和机遇。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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