Talasemi Hastalarında Karaciğer Demir Ölçümünde T2*-ADC Karşılaştırması

İbrahim Yeni̇çeri̇, Bünyamin Güney, F. Azik, Neşat Çullu, Volkan Karakuş
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Abstract

Comparison of T2* MRI with diffusion weigthed imaging in liver iron burden SUMMARY Objective: Repetitive transfusion is a treatment option in patients with thalassemia, but this causes iron accumulation in various organs, especially the liver. In this study, it is aimed to present our own experience in the correlation of serum ferritin concentrations with liver T2* MR measurements and ADC values in thalassemia patients. Materials and methods: Forty consecutive patients who underwent T2* MR examination of the liver due to beta thalassemia were included in the study. T2* and ADC measurements were made from 4 different regions of the liver, one each from the medial and lateral segments of the left lobe and one each from the anterior and posterior segments of the right lobe. Results: Seventeen (42.5%) cases were female and 23 (57.5%) were male. There was a moderate correlation between serum ferritin and mean R2* (r=0531 p
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地贫患者肝脏铁质测量中的 T2*-ADC 比较
T2* MRI 与弥散加权成像在肝脏铁负荷方面的比较 摘要 目的:重复输血是地中海贫血患者的一种治疗选择,但这会导致铁在各个器官,尤其是肝脏中蓄积。本研究旨在介绍地中海贫血患者血清铁蛋白浓度与肝脏 T2* MR 测量值和 ADC 值之间的相关性。材料和方法:本研究连续纳入了 40 名因地中海贫血而接受肝脏 T2* MR 检查的患者。对肝脏的 4 个不同区域进行了 T2* 和 ADC 测量,左叶的内侧和外侧各一个,右叶的前部和后部各一个。结果17例(42.5%)为女性,23例(57.5%)为男性。血清铁蛋白与平均 R2* 之间存在中度相关性(r=0531 p
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