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COMPARISON OF SPERM DEFORMITY INDEXES BETWEEN PATIENTS WHO HAVE AND HAVE NOT EXPERIENCED COVID-19 精子畸形指数在经历过和未经历过 covid-19 的患者之间的比较
Pub Date : 2024-01-05 DOI: 10.38175/phnx.1406623
Deniz AKA SATAR, Ridvan Bagci, Umut Demi̇rdelen
Objective: Ever since its identification in December 2019, the novel coronavirus SARS-CoV-2 has rapidly disseminated worldwide, giving rise to the COVID-19 (coronavirus disease-19) pandemic. The male reproductive system is susceptible to the effects of COVID-19, leading to potential alterations in semen parameters. In this study, we conducted a comparison between patients who have previously contracted COVID-19 and those who have not, specifically focusing on the sperm deformity index (SDI) as a parameter for assessing sperm morphology. Material and Method: 134 patients over the age of 18 who applied to Hospital Andrology Laboratory between 29 November 2022 and 29 December 2022 were included in the study. Of these, 44 were patients who have had COVID-19, and 90 were patients who have not had COVID-19. These patients were compared in terms of SDI parameter and other semen parameters (ejaculate volume, sperm concentration, total sperm count, total motility, progressive motility and percentage of normal morphology sperm). The calculation of the SDI was performed by dividing the total number of observed deformities by the total count of sperm. Results: A noteworthy distinction was observed in the SDI values between the two groups, with a statistically significant difference (p0.05). Conclusion: SDI, one of the semen parameters, was found to be significantly different in both groups. Further comprehensive studies are warranted to thoroughly investigate the impact of COVID-19 on semen parameters.
目的:自 2019 年 12 月发现新型冠状病毒 SARS-CoV-2 以来,该病毒在全球迅速传播,引发了 COVID-19(冠状病毒病-19)大流行。男性生殖系统易受 COVID-19 的影响,导致精液参数的潜在改变。在本研究中,我们对曾感染过 COVID-19 和未感染过 COVID-19 的患者进行了比较,特别是将精子畸形指数(SDI)作为评估精子形态的参数。材料与方法研究对象包括在 2022 年 11 月 29 日至 2022 年 12 月 29 日期间向医院 Andrology 实验室提出申请的 134 名 18 岁以上患者。其中,44 名患者接受过 COVID-19 治疗,90 名患者未接受过 COVID-19 治疗。这些患者的 SDI 参数与其他精液参数(射精量、精子浓度、精子总数、总活力、渐进活力和正常形态精子百分比)进行了比较。SDI 的计算方法是将观察到的畸形总数除以精子总数。结果两组的 SDI 值有显著差异,差异有统计学意义(P0.05)。结论作为精液参数之一的 SDI 值在两组中均有显著差异。有必要开展进一步的综合研究,以深入探讨 COVID-19 对精液参数的影响。
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引用次数: 0
Talasemi Hastalarında Karaciğer Demir Ölçümünde T2*-ADC Karşılaştırması 地贫患者肝脏铁质测量中的 T2*-ADC 比较
Pub Date : 2024-01-02 DOI: 10.38175/phnx.1290224
İbrahim Yeni̇çeri̇, Bünyamin Güney, F. Azik, Neşat Çullu, Volkan Karakuş
Comparison of T2* MRI with diffusion weigthed imaging in liver iron burden SUMMARY Objective: Repetitive transfusion is a treatment option in patients with thalassemia, but this causes iron accumulation in various organs, especially the liver. In this study, it is aimed to present our own experience in the correlation of serum ferritin concentrations with liver T2* MR measurements and ADC values in thalassemia patients. Materials and methods: Forty consecutive patients who underwent T2* MR examination of the liver due to beta thalassemia were included in the study. T2* and ADC measurements were made from 4 different regions of the liver, one each from the medial and lateral segments of the left lobe and one each from the anterior and posterior segments of the right lobe. Results: Seventeen (42.5%) cases were female and 23 (57.5%) were male. There was a moderate correlation between serum ferritin and mean R2* (r=0531 p
T2* MRI 与弥散加权成像在肝脏铁负荷方面的比较 摘要 目的:重复输血是地中海贫血患者的一种治疗选择,但这会导致铁在各个器官,尤其是肝脏中蓄积。本研究旨在介绍地中海贫血患者血清铁蛋白浓度与肝脏 T2* MR 测量值和 ADC 值之间的相关性。材料和方法:本研究连续纳入了 40 名因地中海贫血而接受肝脏 T2* MR 检查的患者。对肝脏的 4 个不同区域进行了 T2* 和 ADC 测量,左叶的内侧和外侧各一个,右叶的前部和后部各一个。结果17例(42.5%)为女性,23例(57.5%)为男性。血清铁蛋白与平均 R2* 之间存在中度相关性(r=0531 p
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引用次数: 0
Evaluation Of Hearing Functions Of Children With Type 1 Diabetes: A 2-Year Retrospective Study 评估 1 型糖尿病患儿的听力功能:一项为期两年的回顾性研究
Pub Date : 2023-12-21 DOI: 10.38175/phnx.1378911
Emine Tuğba Yorulmaz, Fatmanur Uysal, Seyra Erbek
Introduction: Our study aims to investigate the differences in pure tone audiometry and tympanograms in terms of gender, disease duration, and right-left ear in children with Type 1 diabetes mellitus (Type 1 DM). Materials and methods: For our study, a total of 109 patients between the ages of 0-18 who were diagnosed with Type 1 DM between 2016-2017 were identified. Among these, 26 children, 52 ears, aged between 2-18, who applied to the Ear Nose Throat outpatient clinic for different reasons and had anamnesis and examination information, were included. Then, hearing thresholds and middle ear functions were evaluated by looking at pure-tone audiometers and tympanograms. Whether the patients met the study criteria was retrospectively determined by using the patient registration forms filled out by the pediatric endocrinology. Results: In the measurements made for the right and left ears, the conduction threshold values at a frequency of 4000 and 8000 Hz were found to be statistically significantly higher values in the Type 1 DM patient group for 5 years and longer than the control group with Type 1 DM for less than 5 years (p
简介我们的研究旨在调查 1 型糖尿病(DM)患儿纯音测听和鼓室造影在性别、病程和左右耳方面的差异。 材料和方法在我们的研究中,共确定了109名在2016-2017年间被诊断为1型糖尿病的0-18岁患者。其中,因不同原因到耳鼻喉科门诊就诊的儿童26名,耳朵52只,年龄在2-18岁之间,并有相关的病史和检查资料。然后,通过纯音听力计和鼓室造影对听阈和中耳功能进行评估。根据小儿内分泌科填写的患者登记表,回顾性地确定患者是否符合研究标准。 研究结果在对左右耳的测量中发现,在频率为 4000 和 8000 Hz 时,1 型糖尿病患者组的传导阈值在统计学上明显高于治疗 5 年及以上的 1 型糖尿病对照组(P<0.05)。
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引用次数: 0
Prolonged Air Leak After Pleurectomy/Decortication Surgery in Two Patients with COVID-19 Pneumonia 两名 COVID-19 肺炎患者胸膜切除/去皮质手术后长期漏气
Pub Date : 2023-11-02 DOI: 10.38175/phnx.1231855
Merve Şatir, Ismail Tombul, M. Sayan, Ali Çelik, A. Tastepe
Surgical treatment is a part of multimodal treatment in patients with malignant pleural mesothelioma in appropriate clinical stage and medical condition. The pleurectomy/decortication is a surgical technique for mesothelioma and its challenging morbidity is prolonged air leak. In case of prolonged air leakage, both the duration of tube thoracostomy and the risk of its complications increase. An increase in this complication is expected due to reasons such as pleural adhesions developing as a result of exaggerated inflammation in COVID-19 pneumonia and increased susceptibility to tearing in the alveoli. Here, we present the treatment of prolonged air leak after pleurectomy-decortication surgery in 2 cases of malignant pleural mesothelioma who were scheduled for surgery after induction therapy and who developed COVID-19 pneumonia during the preparation process.
对于临床分期和病情适当的恶性胸膜间皮瘤患者,手术治疗是多模式治疗的一部分。胸膜切除术是治疗间皮瘤的一种外科技术,其具有挑战性的发病率是长期漏气。如果长期漏气,管式胸腔造口术的持续时间及其并发症的风险都会增加。由于 COVID-19 肺炎的炎症加剧导致胸膜粘连,以及肺泡更易撕裂等原因,预计这种并发症会增加。在此,我们介绍了2例恶性胸膜间皮瘤患者胸膜切除-去皮层手术后长期漏气的治疗方法,这些患者在诱导治疗后被安排进行手术,并在准备过程中出现了COVID-19肺炎。
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引用次数: 0
Telerehabilitation in Survival Breast Cancer Patients: Need For Randomized Controlled Studies 远程康复在乳腺癌患者生存中的应用:需要进行随机对照研究
Pub Date : 2023-07-26 DOI: 10.38175/phnx.1220330
Ramazan Cihad Yilmaz, Deniz Kocamaz, Nahide AYHAN FİDANCIOĞLU
On the importance of telerehabilitation in survival breast cancer patients
远程康复对乳腺癌患者生存的重要性
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引用次数: 0
Yara Örneklerinde Üreyen Etkenler ve Antibakteriyel Duyarlılık. 伤口样本中的生长剂和抗菌敏感性
Pub Date : 2023-07-20 DOI: 10.38175/phnx.1295490
Feray Ferda Şenol, Yüksel Akkaya, Arzu Şenol, İlkay Bahçeci̇, Pinar Öner, Özlem Aytaç, Sevda Soydan, Zülal AŞCI TORAMAN
Amaç:Hastane kaynaklı enfeksiyonlar arasında yer alan yara enfeksiyonları az gelişmiş ve gelişmekte olan ülkeler için büyük bir sağlık sorunudur. Çalışmamızda yara enfeksiyonuna neden olan etkenler ve bu etkenlerin antibakteriyel duyarlılığının belirlenmesi amaçlanmıştır. Gereç ve Yöntem:1290 yara sürüntü örneği retrospektif olarak değerlendirildi. Etken olarak düşündüğümüz mikroorganizmaların tür düzeyinde tanımlanmaları ve antibakteriyel duyarlılıkları konvansiyoner ve VITEK-2 otomatize sistem ile çalışıldı. Bulgular:Örneklerin 505’inde bakteriyel, 16’sında mantarlar etken olarak izole edildi. İzole edilen bakteriyel etkenlerin; %60’ını Gram negatif bakteriler, %40’ını Gram pozitif bakteriler oluşturuyordu. Bakteriyel etkenler içinde en sık izole edilen bakteri 143 (%28.31) örnekle Staphylococcus aureus (S.aureus) bunu 121 (%24) örnekle Escherichia coli (E. coli), 47 (%9.30) örnekle Acinetobacter baumannii (A. baumanii), 46 (%9.10) örnekle Pseudomonas aeruginosa (P. aeruginosa) takip etti. Bu mikroorganizmaların en sık izole edildikleri servislere göre dağılımı ise S.aureus polikliniklerden, E.coli ve P.aeruginosa yatan hasta servislerinden, A. Baumanii yoğun bakım ünitelerinden saptandı. S.aureus’ların 61 (%42.65)’i metisiline dirençli bulunurken tigesiklin, vankomicin ve linezolid’e direnç saptanmadı. E.coli’ ye karşı en dirençli antibakteriyel ampisilin 111 (%91.73) hasta, en duyarlı antibakteriyel imipenem ve meropenem 118 (%97.52) hasta olarak saptandı. A. Baumanii’ye karşı antibakteriyellerin hepsinde yüksek direnç saptanırken kolistine karşı direnç saptanmadı. P. aeruginosa’ya karşı en dirençli antibakteriyel sefepim ve imipenem 14 (%29.78) hasta da saptanırken kolistine karşı direnç saptanmadı. Sonuç:İzole edilen mikroorganizmaların ve antibiyotik duyarlılıklarının bilinmesi, ampirik tedavilere yön verebilmek, hekimlerin kontrollü ve akılcı antibiyotik kullanımı konusunda bilinçlenmesini sağlayacaktır
目的:伤口感染是医院获得性感染的一种,是欠发达国家和发展中国家的一个主要健康问题。我们的研究旨在确定伤口感染的致病菌及其抗菌敏感性。 材料和方法:我们对 1290 份伤口拭子样本进行了回顾性分析。采用传统方法和 VITEK-2 自动系统对被视为致病菌的微生物进行物种鉴定,并确定其抗菌药敏感性。 结果:分别在 505 份和 16 份样本中分离出细菌和真菌病原体。在分离出的细菌病原体中,60%为革兰氏阴性菌,40%为革兰氏阳性菌。最常分离到的细菌病原体是金黄色葡萄球菌(S.aureus),有 143 个样本(28.31%),其次是大肠埃希菌(E.coli),有 121 个样本(24%),鲍曼不动杆菌(A.baumanii)有 47 个样本(9.30%),铜绿假单胞菌(P.aeruginosa)有 46 个样本(9.10%)。这些微生物按其最常分离的服务分布情况为:金黄色葡萄球菌来自门诊,大肠杆菌和铜绿假单胞菌来自住院病房,鲍曼不动杆菌来自重症监护室。61(42.65%)个金黄色葡萄球菌对甲氧西林有耐药性,但对替加环素、万古霉素和利奈唑胺没有耐药性。在 111 名(91.73%)患者中,对大肠杆菌最耐药的抗菌药是氨苄西林,而在 118 名(97.52%)患者中,最敏感的抗菌药是亚胺培南和美罗培南。所有抗菌药物对鲍曼不动杆菌都有很高的耐药性,而对可乐定没有耐药性。对铜绿假单胞菌耐药最多的抗菌药是头孢吡肟和亚胺培南,有 14 名患者(29.78%)对这两种抗菌药耐药,而对秋水仙碱没有发现耐药。 结论:了解分离出的微生物及其对抗生素的敏感性将为经验性治疗提供指导,并提高医生对控制和合理使用抗生素的认识。
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引用次数: 0
Evaluation of Vitamin D Levels in Kütahya Province: A Hospital-Based Retrospective Study 库塔赫亚省维生素 D 水平评估:一项基于医院的回顾性研究
Pub Date : 2023-07-14 DOI: 10.38175/phnx.1259661
Özlem Arik, Inci Arikan, T. Pasali Kilit, Havva Koçak
Introduction: The general health status and quality of life of people are adversely affected by the symptoms that occur due to vitamin D deficiency, which is a steroid vitamin that is synthesized in the skin by 90-95% under the influence of sunlight. The aim of the study is to evaluate the vitamin D status of outpatients admitted to Kütahya Health Sciences University Evliya Çelebi Training and Research Hospital between 2017-2021 according to age, gender and season. Material and Methods: Those whose 25-Hydroxy Vitamin D (25-OH VitD) levels were studied were retrospectively analyzed from the hospital database system. 121727 patients were included in the study. Factors affecting vitamin D deficiency were determined by logistic regression method and risk assessments were made between categories. Results: The mean and standard deviation values of 25-OH VitD levels were 16.73±11.11 ng/ml. When 20 ng/ml is taken as the cut-off value; 71.5% of the patients had vitamin D deficiency. Vitamin D levels were found to be lower especially in the winter season, in women, and with increasing age. Conclusion: It has been shown that vitamin D deficiency is common in patients admitted to the hospital in Kütahya. We think that benefiting more from sunlight in the spring and summer seasons, and dietary and lifestyle changes will positively affect the vitamin D level.
导言:维生素 D 是一种类固醇维生素,90%-95% 的维生素是在阳光照射下在皮肤中合成的。本研究的目的是根据年龄、性别和季节,评估库塔希亚卫生科学大学埃夫利亚-切莱比培训与研究医院 2017-2021 年期间门诊患者的维生素 D 状态。 材料与方法:对医院数据库系统中25-羟基维生素D(25-OH VitD)水平进行回顾性分析。研究共纳入 121727 名患者。通过逻辑回归法确定了影响维生素 D 缺乏的因素,并对不同类别的患者进行了风险评估。 研究结果25-OH 维生素 D 水平的平均值和标准差为 16.73±11.11 纳克/毫升。以 20 ng/ml 为临界值,71.5% 的患者存在维生素 D 缺乏症。研究发现,维生素 D 水平较低,尤其是在冬季、女性和随着年龄的增长。 结论事实表明,库塔赫亚医院的住院病人普遍缺乏维生素 D。我们认为,在春季和夏季多晒太阳、改变饮食和生活方式将对维生素 D 水平产生积极影响。
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引用次数: 0
THE PROGNOSTIC IMPORTANCE OF C REACTIVE PORETIN ALBUMIN RATIO AND HEMATOLOGICAL PARAMETERS IN SUDDEN HEARİNG LOSS C 反应蛋白白蛋白比率和血液学参数对突发性神经损伤预后的重要性
Pub Date : 2023-07-11 DOI: 10.38175/phnx.1239411
Muhammed Gazi Yıldız, Israfil Orhan, A. Doğaner
Amaç: Çalışmanın amacı Ani İşitme Kaybının(AİK) prognozunda C reaktif protein / albümin oranı(CAO) ve hemoglobin, nötrofil, lenfosit, trombosit, ortalama trombosit hacmi(MPV), Nötrofil/Lenfosit oranı(NLO), Trombosit / Lenfosit oranı(TLO) ve Sistemik İmmun İnflamasyon İndeksi(Sİİ) gibi hematolojik parametrelerin etkisini araştırmaktır. Gereç ve Yöntemler: Çalışma 66 AİK tanısı olan hasta grubu ve 66 sağlıklı kontrol grubu olacak şekilde planlandı. Hastaların tedavi öncesi hemogram parametreleri ve işitme testleri incelendi. Ani işitme kaybı olan hastalar tedavi sonrası iyileşenler ve iyileşmeyenler olarak sınıflandırıldı. Gruplar arası CAO ve hematolojik parametreler karşılaştırıldı. Bulgular: Hasta grupta CRP hariç diğer parametreler istatistiksel olarak anlamlı saptandı. Recevier Operator Curve(ROC) analizinde hasta grupta NLO,TLO, Sİİ, MPV ve CAO değerlerinin AİK grubunda ayrım gücü istatistiksel olarak anlamlı idi. Ayrıca AİK grubunda iyileşmeyenlerde ise nötrofil dışındaki diğer parametreler istatistiksel olarak anlamlı idi. ROC analizinde ise NLO,TLO, Sİİ, MPV ve CAO değerleri istatistiksel anlamlı yüksek saptandı. Sonuç: Ani işitme kaybı olan hastalarda maliyeti düşük, kolay elde edilen CAO, NLO,TLO,MPV ve Sİİ prognozun belirlenmesinde prediktif gösterge olarak kullanılabilir.
研究目的本研究旨在探讨 C 反应蛋白/白蛋白比值(CAO)以及血红蛋白、中性粒细胞、淋巴细胞、血小板、平均血小板体积(MPV)、中性粒细胞/淋巴细胞比值(NLO)、血小板/淋巴细胞比值(TLO)和系统免疫炎症指数(SII)等血液学参数对突发性听力损失(SHL)预后的影响。 材料与方法:研究计划包括 66 名 AIC 患者和 66 名健康对照者。在治疗前对患者的血液学参数和听力测试进行分析。治疗后,突发性听力损失患者被分为痊愈和未痊愈两类。比较各组之间的 CAO 和血液学参数。 结果:除 CRP 外,患者组的所有参数均有统计学意义。在 ROC 分析中,患者组的 NLO、TLO、SII、MPV 和 CAO 值对 AIK 组的分辨力具有统计学意义。此外,在 AIC 组中,除中性粒细胞外,其他参数在未愈合组中也有统计学意义。在 ROC 分析中,发现 NLO、TLO、SII、MPV 和 CAO 值在统计学上显著较高。 结论CAO、NLO、TLO、MPV 和 SI 成本低廉且易于获得,可用作突发性听力损失患者预后的预测指标。
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引用次数: 0
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Phoenix Medical Journal
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