Objective: Ever since its identification in December 2019, the novel coronavirus SARS-CoV-2 has rapidly disseminated worldwide, giving rise to the COVID-19 (coronavirus disease-19) pandemic. The male reproductive system is susceptible to the effects of COVID-19, leading to potential alterations in semen parameters. In this study, we conducted a comparison between patients who have previously contracted COVID-19 and those who have not, specifically focusing on the sperm deformity index (SDI) as a parameter for assessing sperm morphology. Material and Method: 134 patients over the age of 18 who applied to Hospital Andrology Laboratory between 29 November 2022 and 29 December 2022 were included in the study. Of these, 44 were patients who have had COVID-19, and 90 were patients who have not had COVID-19. These patients were compared in terms of SDI parameter and other semen parameters (ejaculate volume, sperm concentration, total sperm count, total motility, progressive motility and percentage of normal morphology sperm). The calculation of the SDI was performed by dividing the total number of observed deformities by the total count of sperm. Results: A noteworthy distinction was observed in the SDI values between the two groups, with a statistically significant difference (p0.05). Conclusion: SDI, one of the semen parameters, was found to be significantly different in both groups. Further comprehensive studies are warranted to thoroughly investigate the impact of COVID-19 on semen parameters.
{"title":"COMPARISON OF SPERM DEFORMITY INDEXES BETWEEN PATIENTS WHO HAVE AND HAVE NOT EXPERIENCED COVID-19","authors":"Deniz AKA SATAR, Ridvan Bagci, Umut Demi̇rdelen","doi":"10.38175/phnx.1406623","DOIUrl":"https://doi.org/10.38175/phnx.1406623","url":null,"abstract":"Objective: Ever since its identification in December 2019, the novel coronavirus SARS-CoV-2 has rapidly disseminated worldwide, giving rise to the COVID-19 (coronavirus disease-19) pandemic. The male reproductive system is susceptible to the effects of COVID-19, leading to potential alterations in semen parameters. In this study, we conducted a comparison between patients who have previously contracted COVID-19 and those who have not, specifically focusing on the sperm deformity index (SDI) as a parameter for assessing sperm morphology. \u0000Material and Method: 134 patients over the age of 18 who applied to Hospital Andrology Laboratory between 29 November 2022 and 29 December 2022 were included in the study. Of these, 44 were patients who have had COVID-19, and 90 were patients who have not had COVID-19. These patients were compared in terms of SDI parameter and other semen parameters (ejaculate volume, sperm concentration, total sperm count, total motility, progressive motility and percentage of normal morphology sperm). The calculation of the SDI was performed by dividing the total number of observed deformities by the total count of sperm. \u0000Results: A noteworthy distinction was observed in the SDI values between the two groups, with a statistically significant difference (p0.05). \u0000Conclusion: SDI, one of the semen parameters, was found to be significantly different in both groups. Further comprehensive studies are warranted to thoroughly investigate the impact of COVID-19 on semen parameters.","PeriodicalId":503064,"journal":{"name":"Phoenix Medical Journal","volume":"18 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139383961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
İbrahim Yeni̇çeri̇, Bünyamin Güney, F. Azik, Neşat Çullu, Volkan Karakuş
Comparison of T2* MRI with diffusion weigthed imaging in liver iron burden SUMMARY Objective: Repetitive transfusion is a treatment option in patients with thalassemia, but this causes iron accumulation in various organs, especially the liver. In this study, it is aimed to present our own experience in the correlation of serum ferritin concentrations with liver T2* MR measurements and ADC values in thalassemia patients. Materials and methods: Forty consecutive patients who underwent T2* MR examination of the liver due to beta thalassemia were included in the study. T2* and ADC measurements were made from 4 different regions of the liver, one each from the medial and lateral segments of the left lobe and one each from the anterior and posterior segments of the right lobe. Results: Seventeen (42.5%) cases were female and 23 (57.5%) were male. There was a moderate correlation between serum ferritin and mean R2* (r=0531 p
{"title":"Talasemi Hastalarında Karaciğer Demir Ölçümünde T2*-ADC Karşılaştırması","authors":"İbrahim Yeni̇çeri̇, Bünyamin Güney, F. Azik, Neşat Çullu, Volkan Karakuş","doi":"10.38175/phnx.1290224","DOIUrl":"https://doi.org/10.38175/phnx.1290224","url":null,"abstract":"Comparison of T2* MRI with diffusion weigthed imaging in liver iron burden \u0000 \u0000SUMMARY \u0000 \u0000Objective: Repetitive transfusion is a treatment option in patients with thalassemia, but this causes iron accumulation in various organs, especially the liver. In this study, it is aimed to present our own experience in the correlation of serum ferritin concentrations with liver T2* MR measurements and ADC values in thalassemia patients. \u0000Materials and methods: Forty consecutive patients who underwent T2* MR examination of the liver due to beta thalassemia were included in the study. T2* and ADC measurements were made from 4 different regions of the liver, one each from the medial and lateral segments of the left lobe and one each from the anterior and posterior segments of the right lobe. \u0000Results: Seventeen (42.5%) cases were female and 23 (57.5%) were male. There was a moderate correlation between serum ferritin and mean R2* (r=0531 p","PeriodicalId":503064,"journal":{"name":"Phoenix Medical Journal","volume":"128 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139453459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Our study aims to investigate the differences in pure tone audiometry and tympanograms in terms of gender, disease duration, and right-left ear in children with Type 1 diabetes mellitus (Type 1 DM). Materials and methods: For our study, a total of 109 patients between the ages of 0-18 who were diagnosed with Type 1 DM between 2016-2017 were identified. Among these, 26 children, 52 ears, aged between 2-18, who applied to the Ear Nose Throat outpatient clinic for different reasons and had anamnesis and examination information, were included. Then, hearing thresholds and middle ear functions were evaluated by looking at pure-tone audiometers and tympanograms. Whether the patients met the study criteria was retrospectively determined by using the patient registration forms filled out by the pediatric endocrinology. Results: In the measurements made for the right and left ears, the conduction threshold values at a frequency of 4000 and 8000 Hz were found to be statistically significantly higher values in the Type 1 DM patient group for 5 years and longer than the control group with Type 1 DM for less than 5 years (p
{"title":"Evaluation Of Hearing Functions Of Children With Type 1 Diabetes: A 2-Year Retrospective Study","authors":"Emine Tuğba Yorulmaz, Fatmanur Uysal, Seyra Erbek","doi":"10.38175/phnx.1378911","DOIUrl":"https://doi.org/10.38175/phnx.1378911","url":null,"abstract":"Introduction: Our study aims to investigate the differences in pure tone audiometry and tympanograms in terms of gender, disease duration, and right-left ear in children with Type 1 diabetes mellitus (Type 1 DM). Materials and methods: For our study, a total of 109 patients between the ages of 0-18 who were diagnosed with Type 1 DM between 2016-2017 were identified. Among these, 26 children, 52 ears, aged between 2-18, who applied to the Ear Nose Throat outpatient clinic for different reasons and had anamnesis and examination information, were included. Then, hearing thresholds and middle ear functions were evaluated by looking at pure-tone audiometers and tympanograms. Whether the patients met the study criteria was retrospectively determined by using the patient registration forms filled out by the pediatric endocrinology. Results: In the measurements made for the right and left ears, the conduction threshold values at a frequency of 4000 and 8000 Hz were found to be statistically significantly higher values in the Type 1 DM patient group for 5 years and longer than the control group with Type 1 DM for less than 5 years (p","PeriodicalId":503064,"journal":{"name":"Phoenix Medical Journal","volume":"73 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139166953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Merve Şatir, Ismail Tombul, M. Sayan, Ali Çelik, A. Tastepe
Surgical treatment is a part of multimodal treatment in patients with malignant pleural mesothelioma in appropriate clinical stage and medical condition. The pleurectomy/decortication is a surgical technique for mesothelioma and its challenging morbidity is prolonged air leak. In case of prolonged air leakage, both the duration of tube thoracostomy and the risk of its complications increase. An increase in this complication is expected due to reasons such as pleural adhesions developing as a result of exaggerated inflammation in COVID-19 pneumonia and increased susceptibility to tearing in the alveoli. Here, we present the treatment of prolonged air leak after pleurectomy-decortication surgery in 2 cases of malignant pleural mesothelioma who were scheduled for surgery after induction therapy and who developed COVID-19 pneumonia during the preparation process.
{"title":"Prolonged Air Leak After Pleurectomy/Decortication Surgery in Two Patients with COVID-19 Pneumonia","authors":"Merve Şatir, Ismail Tombul, M. Sayan, Ali Çelik, A. Tastepe","doi":"10.38175/phnx.1231855","DOIUrl":"https://doi.org/10.38175/phnx.1231855","url":null,"abstract":"Surgical treatment is a part of multimodal treatment in patients with malignant pleural mesothelioma in appropriate clinical stage and medical condition. The pleurectomy/decortication is a surgical technique for mesothelioma and its challenging morbidity is prolonged air leak. In case of prolonged air leakage, both the duration of tube thoracostomy and the risk of its complications increase. An increase in this complication is expected due to reasons such as pleural adhesions developing as a result of exaggerated inflammation in COVID-19 pneumonia and increased susceptibility to tearing in the alveoli. Here, we present the treatment of prolonged air leak after pleurectomy-decortication surgery in 2 cases of malignant pleural mesothelioma who were scheduled for surgery after induction therapy and who developed COVID-19 pneumonia during the preparation process.","PeriodicalId":503064,"journal":{"name":"Phoenix Medical Journal","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139290633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ramazan Cihad Yilmaz, Deniz Kocamaz, Nahide AYHAN FİDANCIOĞLU
On the importance of telerehabilitation in survival breast cancer patients
远程康复对乳腺癌患者生存的重要性
{"title":"Telerehabilitation in Survival Breast Cancer Patients: Need For Randomized Controlled Studies","authors":"Ramazan Cihad Yilmaz, Deniz Kocamaz, Nahide AYHAN FİDANCIOĞLU","doi":"10.38175/phnx.1220330","DOIUrl":"https://doi.org/10.38175/phnx.1220330","url":null,"abstract":"On the importance of telerehabilitation in survival breast cancer patients","PeriodicalId":503064,"journal":{"name":"Phoenix Medical Journal","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139354673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amaç:Hastane kaynaklı enfeksiyonlar arasında yer alan yara enfeksiyonları az gelişmiş ve gelişmekte olan ülkeler için büyük bir sağlık sorunudur. Çalışmamızda yara enfeksiyonuna neden olan etkenler ve bu etkenlerin antibakteriyel duyarlılığının belirlenmesi amaçlanmıştır. Gereç ve Yöntem:1290 yara sürüntü örneği retrospektif olarak değerlendirildi. Etken olarak düşündüğümüz mikroorganizmaların tür düzeyinde tanımlanmaları ve antibakteriyel duyarlılıkları konvansiyoner ve VITEK-2 otomatize sistem ile çalışıldı. Bulgular:Örneklerin 505’inde bakteriyel, 16’sında mantarlar etken olarak izole edildi. İzole edilen bakteriyel etkenlerin; %60’ını Gram negatif bakteriler, %40’ını Gram pozitif bakteriler oluşturuyordu. Bakteriyel etkenler içinde en sık izole edilen bakteri 143 (%28.31) örnekle Staphylococcus aureus (S.aureus) bunu 121 (%24) örnekle Escherichia coli (E. coli), 47 (%9.30) örnekle Acinetobacter baumannii (A. baumanii), 46 (%9.10) örnekle Pseudomonas aeruginosa (P. aeruginosa) takip etti. Bu mikroorganizmaların en sık izole edildikleri servislere göre dağılımı ise S.aureus polikliniklerden, E.coli ve P.aeruginosa yatan hasta servislerinden, A. Baumanii yoğun bakım ünitelerinden saptandı. S.aureus’ların 61 (%42.65)’i metisiline dirençli bulunurken tigesiklin, vankomicin ve linezolid’e direnç saptanmadı. E.coli’ ye karşı en dirençli antibakteriyel ampisilin 111 (%91.73) hasta, en duyarlı antibakteriyel imipenem ve meropenem 118 (%97.52) hasta olarak saptandı. A. Baumanii’ye karşı antibakteriyellerin hepsinde yüksek direnç saptanırken kolistine karşı direnç saptanmadı. P. aeruginosa’ya karşı en dirençli antibakteriyel sefepim ve imipenem 14 (%29.78) hasta da saptanırken kolistine karşı direnç saptanmadı. Sonuç:İzole edilen mikroorganizmaların ve antibiyotik duyarlılıklarının bilinmesi, ampirik tedavilere yön verebilmek, hekimlerin kontrollü ve akılcı antibiyotik kullanımı konusunda bilinçlenmesini sağlayacaktır
{"title":"Yara Örneklerinde Üreyen Etkenler ve Antibakteriyel Duyarlılık.","authors":"Feray Ferda Şenol, Yüksel Akkaya, Arzu Şenol, İlkay Bahçeci̇, Pinar Öner, Özlem Aytaç, Sevda Soydan, Zülal AŞCI TORAMAN","doi":"10.38175/phnx.1295490","DOIUrl":"https://doi.org/10.38175/phnx.1295490","url":null,"abstract":"Amaç:Hastane kaynaklı enfeksiyonlar arasında yer alan yara enfeksiyonları az gelişmiş ve gelişmekte olan ülkeler için büyük bir sağlık sorunudur. Çalışmamızda yara enfeksiyonuna neden olan etkenler ve bu etkenlerin antibakteriyel duyarlılığının belirlenmesi amaçlanmıştır. Gereç ve Yöntem:1290 yara sürüntü örneği retrospektif olarak değerlendirildi. Etken olarak düşündüğümüz mikroorganizmaların tür düzeyinde tanımlanmaları ve antibakteriyel duyarlılıkları konvansiyoner ve VITEK-2 otomatize sistem ile çalışıldı. Bulgular:Örneklerin 505’inde bakteriyel, 16’sında mantarlar etken olarak izole edildi. İzole edilen bakteriyel etkenlerin; %60’ını Gram negatif bakteriler, %40’ını Gram pozitif bakteriler oluşturuyordu. Bakteriyel etkenler içinde en sık izole edilen bakteri 143 (%28.31) örnekle Staphylococcus aureus (S.aureus) bunu 121 (%24) örnekle Escherichia coli (E. coli), 47 (%9.30) örnekle Acinetobacter baumannii (A. baumanii), 46 (%9.10) örnekle Pseudomonas aeruginosa (P. aeruginosa) takip etti. Bu mikroorganizmaların en sık izole edildikleri servislere göre dağılımı ise S.aureus polikliniklerden, E.coli ve P.aeruginosa yatan hasta servislerinden, A. Baumanii yoğun bakım ünitelerinden saptandı. S.aureus’ların 61 (%42.65)’i metisiline dirençli bulunurken tigesiklin, vankomicin ve linezolid’e direnç saptanmadı. E.coli’ ye karşı en dirençli antibakteriyel ampisilin 111 (%91.73) hasta, en duyarlı antibakteriyel imipenem ve meropenem 118 (%97.52) hasta olarak saptandı. A. Baumanii’ye karşı antibakteriyellerin hepsinde yüksek direnç saptanırken kolistine karşı direnç saptanmadı. P. aeruginosa’ya karşı en dirençli antibakteriyel sefepim ve imipenem 14 (%29.78) hasta da saptanırken kolistine karşı direnç saptanmadı. Sonuç:İzole edilen mikroorganizmaların ve antibiyotik duyarlılıklarının bilinmesi, ampirik tedavilere yön verebilmek, hekimlerin kontrollü ve akılcı antibiyotik kullanımı konusunda bilinçlenmesini sağlayacaktır","PeriodicalId":503064,"journal":{"name":"Phoenix Medical Journal","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139357352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Özlem Arik, Inci Arikan, T. Pasali Kilit, Havva Koçak
Introduction: The general health status and quality of life of people are adversely affected by the symptoms that occur due to vitamin D deficiency, which is a steroid vitamin that is synthesized in the skin by 90-95% under the influence of sunlight. The aim of the study is to evaluate the vitamin D status of outpatients admitted to Kütahya Health Sciences University Evliya Çelebi Training and Research Hospital between 2017-2021 according to age, gender and season. Material and Methods: Those whose 25-Hydroxy Vitamin D (25-OH VitD) levels were studied were retrospectively analyzed from the hospital database system. 121727 patients were included in the study. Factors affecting vitamin D deficiency were determined by logistic regression method and risk assessments were made between categories. Results: The mean and standard deviation values of 25-OH VitD levels were 16.73±11.11 ng/ml. When 20 ng/ml is taken as the cut-off value; 71.5% of the patients had vitamin D deficiency. Vitamin D levels were found to be lower especially in the winter season, in women, and with increasing age. Conclusion: It has been shown that vitamin D deficiency is common in patients admitted to the hospital in Kütahya. We think that benefiting more from sunlight in the spring and summer seasons, and dietary and lifestyle changes will positively affect the vitamin D level.
导言:维生素 D 是一种类固醇维生素,90%-95% 的维生素是在阳光照射下在皮肤中合成的。本研究的目的是根据年龄、性别和季节,评估库塔希亚卫生科学大学埃夫利亚-切莱比培训与研究医院 2017-2021 年期间门诊患者的维生素 D 状态。 材料与方法:对医院数据库系统中25-羟基维生素D(25-OH VitD)水平进行回顾性分析。研究共纳入 121727 名患者。通过逻辑回归法确定了影响维生素 D 缺乏的因素,并对不同类别的患者进行了风险评估。 研究结果25-OH 维生素 D 水平的平均值和标准差为 16.73±11.11 纳克/毫升。以 20 ng/ml 为临界值,71.5% 的患者存在维生素 D 缺乏症。研究发现,维生素 D 水平较低,尤其是在冬季、女性和随着年龄的增长。 结论事实表明,库塔赫亚医院的住院病人普遍缺乏维生素 D。我们认为,在春季和夏季多晒太阳、改变饮食和生活方式将对维生素 D 水平产生积极影响。
{"title":"Evaluation of Vitamin D Levels in Kütahya Province: A Hospital-Based Retrospective Study","authors":"Özlem Arik, Inci Arikan, T. Pasali Kilit, Havva Koçak","doi":"10.38175/phnx.1259661","DOIUrl":"https://doi.org/10.38175/phnx.1259661","url":null,"abstract":"Introduction: The general health status and quality of life of people are adversely affected by the symptoms that occur due to vitamin D deficiency, which is a steroid vitamin that is synthesized in the skin by 90-95% under the influence of sunlight. The aim of the study is to evaluate the vitamin D status of outpatients admitted to Kütahya Health Sciences University Evliya Çelebi Training and Research Hospital between 2017-2021 according to age, gender and season. Material and Methods: Those whose 25-Hydroxy Vitamin D (25-OH VitD) levels were studied were retrospectively analyzed from the hospital database system. 121727 patients were included in the study. Factors affecting vitamin D deficiency were determined by logistic regression method and risk assessments were made between categories. Results: The mean and standard deviation values of 25-OH VitD levels were 16.73±11.11 ng/ml. When 20 ng/ml is taken as the cut-off value; 71.5% of the patients had vitamin D deficiency. Vitamin D levels were found to be lower especially in the winter season, in women, and with increasing age. Conclusion: It has been shown that vitamin D deficiency is common in patients admitted to the hospital in Kütahya. We think that benefiting more from sunlight in the spring and summer seasons, and dietary and lifestyle changes will positively affect the vitamin D level.","PeriodicalId":503064,"journal":{"name":"Phoenix Medical Journal","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139359548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amaç: Çalışmanın amacı Ani İşitme Kaybının(AİK) prognozunda C reaktif protein / albümin oranı(CAO) ve hemoglobin, nötrofil, lenfosit, trombosit, ortalama trombosit hacmi(MPV), Nötrofil/Lenfosit oranı(NLO), Trombosit / Lenfosit oranı(TLO) ve Sistemik İmmun İnflamasyon İndeksi(Sİİ) gibi hematolojik parametrelerin etkisini araştırmaktır. Gereç ve Yöntemler: Çalışma 66 AİK tanısı olan hasta grubu ve 66 sağlıklı kontrol grubu olacak şekilde planlandı. Hastaların tedavi öncesi hemogram parametreleri ve işitme testleri incelendi. Ani işitme kaybı olan hastalar tedavi sonrası iyileşenler ve iyileşmeyenler olarak sınıflandırıldı. Gruplar arası CAO ve hematolojik parametreler karşılaştırıldı. Bulgular: Hasta grupta CRP hariç diğer parametreler istatistiksel olarak anlamlı saptandı. Recevier Operator Curve(ROC) analizinde hasta grupta NLO,TLO, Sİİ, MPV ve CAO değerlerinin AİK grubunda ayrım gücü istatistiksel olarak anlamlı idi. Ayrıca AİK grubunda iyileşmeyenlerde ise nötrofil dışındaki diğer parametreler istatistiksel olarak anlamlı idi. ROC analizinde ise NLO,TLO, Sİİ, MPV ve CAO değerleri istatistiksel anlamlı yüksek saptandı. Sonuç: Ani işitme kaybı olan hastalarda maliyeti düşük, kolay elde edilen CAO, NLO,TLO,MPV ve Sİİ prognozun belirlenmesinde prediktif gösterge olarak kullanılabilir.
研究目的本研究旨在探讨 C 反应蛋白/白蛋白比值(CAO)以及血红蛋白、中性粒细胞、淋巴细胞、血小板、平均血小板体积(MPV)、中性粒细胞/淋巴细胞比值(NLO)、血小板/淋巴细胞比值(TLO)和系统免疫炎症指数(SII)等血液学参数对突发性听力损失(SHL)预后的影响。 材料与方法:研究计划包括 66 名 AIC 患者和 66 名健康对照者。在治疗前对患者的血液学参数和听力测试进行分析。治疗后,突发性听力损失患者被分为痊愈和未痊愈两类。比较各组之间的 CAO 和血液学参数。 结果:除 CRP 外,患者组的所有参数均有统计学意义。在 ROC 分析中,患者组的 NLO、TLO、SII、MPV 和 CAO 值对 AIK 组的分辨力具有统计学意义。此外,在 AIC 组中,除中性粒细胞外,其他参数在未愈合组中也有统计学意义。在 ROC 分析中,发现 NLO、TLO、SII、MPV 和 CAO 值在统计学上显著较高。 结论CAO、NLO、TLO、MPV 和 SI 成本低廉且易于获得,可用作突发性听力损失患者预后的预测指标。
{"title":"THE PROGNOSTIC IMPORTANCE OF C REACTIVE PORETIN ALBUMIN RATIO AND HEMATOLOGICAL PARAMETERS IN SUDDEN HEARİNG LOSS","authors":"Muhammed Gazi Yıldız, Israfil Orhan, A. Doğaner","doi":"10.38175/phnx.1239411","DOIUrl":"https://doi.org/10.38175/phnx.1239411","url":null,"abstract":"Amaç: Çalışmanın amacı Ani İşitme Kaybının(AİK) prognozunda C reaktif protein / albümin oranı(CAO) ve hemoglobin, nötrofil, lenfosit, trombosit, ortalama trombosit hacmi(MPV), Nötrofil/Lenfosit oranı(NLO), Trombosit / Lenfosit oranı(TLO) ve Sistemik İmmun İnflamasyon İndeksi(Sİİ) gibi hematolojik parametrelerin etkisini araştırmaktır. Gereç ve Yöntemler: Çalışma 66 AİK tanısı olan hasta grubu ve 66 sağlıklı kontrol grubu olacak şekilde planlandı. Hastaların tedavi öncesi hemogram parametreleri ve işitme testleri incelendi. Ani işitme kaybı olan hastalar tedavi sonrası iyileşenler ve iyileşmeyenler olarak sınıflandırıldı. Gruplar arası CAO ve hematolojik parametreler karşılaştırıldı. Bulgular: Hasta grupta CRP hariç diğer parametreler istatistiksel olarak anlamlı saptandı. Recevier Operator Curve(ROC) analizinde hasta grupta NLO,TLO, Sİİ, MPV ve CAO değerlerinin AİK grubunda ayrım gücü istatistiksel olarak anlamlı idi. Ayrıca AİK grubunda iyileşmeyenlerde ise nötrofil dışındaki diğer parametreler istatistiksel olarak anlamlı idi. ROC analizinde ise NLO,TLO, Sİİ, MPV ve CAO değerleri istatistiksel anlamlı yüksek saptandı. Sonuç: Ani işitme kaybı olan hastalarda maliyeti düşük, kolay elde edilen CAO, NLO,TLO,MPV ve Sİİ prognozun belirlenmesinde prediktif gösterge olarak kullanılabilir.","PeriodicalId":503064,"journal":{"name":"Phoenix Medical Journal","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139360436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}