Characterization of Axillary Lymph Nodes Using Conventional Ultrasonography Compared with Histopathological Findings

Irin Farhana, Sayed Zoherul Alam, Md Nurul Islam Raisul, Zahirul Islam
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Abstract

A cross-sectional, observational study was carried out the Department of Radiology and Imaging, Combined Military Hospital (CMH) at Dhaka Cantonment, Bangladesh, between March and August of 2021. A total of 75 female patients were included presenting with or without axillary swelling referred for ultrasound of breasts and axilla from various surgical and medical departments of the same hospital. B-mode ultrasonography was used as method of choice because of its noninvasiveness and availability in evaluating the axillary lymph nodes. Histopathological diagnosis was considered the gold standard for the diagnosis. The average age was 42.62±8.76 years. In conventional ultrasonography results, 33.3% were benign lymph node, 14.7% were reactive and 52% were metastatic lymph node. Based on the histopathological reports, lymph node involvement was detected in 18(24%) patients with benign, 13(17.3%) patients reactive and 44(58.7%) metastatic. The overall results revealed 79.5% sensitivity, 87.1% specificity, 89.7% PPV and 75% NPV. To summarize, conventional ultrasonography was moderately sensitive with good specificity for diagnosis of axillary lymph node. Further studies with a larger population and intra-operative axillary lymph node are recommended. CBMJ 2024 January: vol. 13 no. 01 P: 3-8
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腋窝淋巴结的常规超声诊断与组织病理学检查结果比较
2021 年 3 月至 8 月期间,孟加拉国达卡县联合军事医院(CMH)放射与影像科开展了一项横断面观察性研究。该研究共纳入了 75 名女性患者,她们或有腋窝肿胀,或无腋窝肿胀,均转诊至同一医院的外科和内科进行乳房和腋窝超声检查。由于 B 型超声波检查无创伤且可用于评估腋窝淋巴结,因此被作为首选方法。组织病理学诊断被认为是诊断的金标准。平均年龄为(42.62±8.76)岁。在常规超声波检查结果中,33.3%为良性淋巴结,14.7%为反应性淋巴结,52%为转移性淋巴结。根据组织病理学报告,18(24%)名良性患者的淋巴结受累,13(17.3%)名反应性患者的淋巴结受累,44(58.7%)名转移性患者的淋巴结受累。总体结果显示,敏感性为 79.5%,特异性为 87.1%,PPV 为 89.7%,NPV 为 75%。总之,常规超声波检查对腋窝淋巴结诊断的敏感性和特异性均较高。建议对更多人群和术中腋窝淋巴结进行进一步研究。
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