{"title":"Cellular Self-Digestion Unveiled: Autophagy's Impact on Cancer","authors":"Ashiqur Rahman Khan Chowdhury, I. B. Naser","doi":"10.3329/cbmj.v13i1.71096","DOIUrl":null,"url":null,"abstract":"Autophagy is a strictly controlled process in which cells break down and recycle their own components by transporting them to lysosomes. Multiple studies have shown that autophagy has a diverse range of physiological and pathological functions in cells. Autophagy in cancer has contradictory functions, serving as both a suppressor and a driver of tumor growth. Specifically, it may exhibit several roles in relation to cancer treatment, either leading to cancer resistance or enhancing susceptibility to radiation and chemotherapy. Hence, autophagy has the potential to augment the efficacy of anticancer medications and radiation treatment. \nCBMJ 2024 January: vol. 13 no. 01 P: 107-118","PeriodicalId":10576,"journal":{"name":"Community Based Medical Journal","volume":"6 6","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Community Based Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3329/cbmj.v13i1.71096","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Autophagy is a strictly controlled process in which cells break down and recycle their own components by transporting them to lysosomes. Multiple studies have shown that autophagy has a diverse range of physiological and pathological functions in cells. Autophagy in cancer has contradictory functions, serving as both a suppressor and a driver of tumor growth. Specifically, it may exhibit several roles in relation to cancer treatment, either leading to cancer resistance or enhancing susceptibility to radiation and chemotherapy. Hence, autophagy has the potential to augment the efficacy of anticancer medications and radiation treatment.
CBMJ 2024 January: vol. 13 no. 01 P: 107-118
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