Direzione Scientifica, S. Squatrito, Catania Direttore, Responsabile Stefano Melloni, Maurizio Sabrina Scilletta, D. Marco, Nicoletta Miano, Agnese Filippello, S. D. Mauro, Alessandra Scamporrino, Marco Musmeci, Giuseppe Coppolino, F. di, Giacomo Barbagallo, Giosiana Bosco, Roberto Scicali, S. Piro, Francesco Purrello, A. Pino
{"title":"Update sulla malattia renale diabetica (DKD): focus sulla DKD non albuminurica e il rischio cardiovascolare","authors":"Direzione Scientifica, S. Squatrito, Catania Direttore, Responsabile Stefano Melloni, Maurizio Sabrina Scilletta, D. Marco, Nicoletta Miano, Agnese Filippello, S. D. Mauro, Alessandra Scamporrino, Marco Musmeci, Giuseppe Coppolino, F. di, Giacomo Barbagallo, Giosiana Bosco, Roberto Scicali, S. Piro, Francesco Purrello, A. Pino","doi":"10.30682/ildia2304a","DOIUrl":null,"url":null,"abstract":"The classic description of diabetic kidney disease (DKD) involves progressive stages of glomerular hyperfiltration, microalbuminuria, and a decline in the estimated glomerular filtration rate (eGFR). However, large studies have revealed that eGFR decline may also occur independently from development of albuminuria. This concept led to the identification of a new phenotype: non-albuminuric DKD, whose pathogenesis is still unknown and data in literature are still controversial. This review is focused on cardiovascular risk profile and therapeutical implication of this new DKD phenotype.","PeriodicalId":119243,"journal":{"name":"Il Diabete","volume":" 7","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Il Diabete","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30682/ildia2304a","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
The classic description of diabetic kidney disease (DKD) involves progressive stages of glomerular hyperfiltration, microalbuminuria, and a decline in the estimated glomerular filtration rate (eGFR). However, large studies have revealed that eGFR decline may also occur independently from development of albuminuria. This concept led to the identification of a new phenotype: non-albuminuric DKD, whose pathogenesis is still unknown and data in literature are still controversial. This review is focused on cardiovascular risk profile and therapeutical implication of this new DKD phenotype.
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