Artificial intelligence approaches for early detection of neurocognitive disorders among older adults

IF 2.1 4区 医学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Frontiers in Computational Neuroscience Pub Date : 2024-02-16 DOI:10.3389/fncom.2024.1307305
Khalid AlHarkan, Nahid Sultana, Noura Al Mulhim, Assim AlAbdulqader, Noor Alsafwani, Marwah Barnawi, Khulud Alasqah, Anhar Bazuhair, Zainab Alhalwah, Dina Bokhamseen, Sumayh S Aljameel, Sultan Alamri, Yousef Alqurashi, Kholoud Alghamdi
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Abstract

IntroductionDementia is one of the major global health issues among the aging population, characterized clinically by a progressive decline in higher cognitive functions. This paper aims to apply various artificial intelligence (AI) approaches to detect patients with mild cognitive impairment (MCI) or dementia accurately.MethodsQuantitative research was conducted to address the objective of this study using randomly selected 343 Saudi patients. The Chi-square test was conducted to determine the association of the patient’s cognitive function with various features, including demographical and medical history. Two widely used AI algorithms, logistic regression and support vector machine (SVM), were used for detecting cognitive decline. This study also assessed patients’ cognitive function based on gender and developed the predicting models for males and females separately.ResultsFifty four percent of patients have normal cognitive function, 34% have MCI, and 12% have dementia. The prediction accuracies for all the developed models are greater than 71%, indicating good prediction capability. However, the developed SVM models performed the best, with an accuracy of 93.3% for all patients, 94.4% for males only, and 95.5% for females only. The top 10 significant predictors based on the developed SVM model are education, bedtime, taking pills for chronic pain, diabetes, stroke, gender, chronic pains, coronary artery diseases, and wake-up time.ConclusionThe results of this study emphasize the higher accuracy and reliability of the proposed methods in cognitive decline prediction that health practitioners can use for the early detection of dementia. This research can also stipulate substantial direction and supportive intuitions for scholars to enhance their understanding of crucial research, emerging trends, and new developments in future cognitive decline studies.
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早期发现老年人神经认知障碍的人工智能方法
导言痴呆症是全球老龄人口的主要健康问题之一,其临床特征是高级认知功能逐渐下降。本文旨在应用各种人工智能(AI)方法来准确检测轻度认知障碍(MCI)或痴呆症患者。通过卡方检验确定了患者认知功能与各种特征(包括人口统计学和病史)之间的关联。两种广泛使用的人工智能算法--逻辑回归和支持向量机(SVM)被用于检测认知功能衰退。本研究还根据性别评估了患者的认知功能,并分别为男性和女性开发了预测模型。结果54%的患者认知功能正常,34%的患者患有 MCI,12%的患者患有痴呆症。所有已开发模型的预测准确率均大于 71%,显示出良好的预测能力。然而,所开发的 SVM 模型表现最佳,对所有患者的预测准确率为 93.3%,对男性患者的预测准确率为 94.4%,对女性患者的预测准确率为 95.5%。根据所开发的 SVM 模型,前 10 个重要的预测因素是教育程度、就寝时间、服用慢性疼痛药物、糖尿病、中风、性别、慢性疼痛、冠状动脉疾病和起床时间。这项研究还为学者们提供了实质性的方向和支持性的直觉,以加强他们对未来认知衰退研究的关键研究、新兴趋势和新发展的理解。
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来源期刊
Frontiers in Computational Neuroscience
Frontiers in Computational Neuroscience MATHEMATICAL & COMPUTATIONAL BIOLOGY-NEUROSCIENCES
CiteScore
5.30
自引率
3.10%
发文量
166
审稿时长
6-12 weeks
期刊介绍: Frontiers in Computational Neuroscience is a first-tier electronic journal devoted to promoting theoretical modeling of brain function and fostering interdisciplinary interactions between theoretical and experimental neuroscience. Progress in understanding the amazing capabilities of the brain is still limited, and we believe that it will only come with deep theoretical thinking and mutually stimulating cooperation between different disciplines and approaches. We therefore invite original contributions on a wide range of topics that present the fruits of such cooperation, or provide stimuli for future alliances. We aim to provide an interactive forum for cutting-edge theoretical studies of the nervous system, and for promulgating the best theoretical research to the broader neuroscience community. Models of all styles and at all levels are welcome, from biophysically motivated realistic simulations of neurons and synapses to high-level abstract models of inference and decision making. While the journal is primarily focused on theoretically based and driven research, we welcome experimental studies that validate and test theoretical conclusions. Also: comp neuro
期刊最新文献
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