首页 > 最新文献

Frontiers in Computational Neuroscience最新文献

英文 中文
A combinatorial deep learning method for Alzheimer's disease classification-based merging pretrained networks. 基于合并预训练网络的阿尔茨海默病分类组合式深度学习方法。
IF 2.1 4区 医学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2024-10-17 eCollection Date: 2024-01-01 DOI: 10.3389/fncom.2024.1444019
Houmem Slimi, Ala Balti, Sabeur Abid, Mounir Sayadi

Introduction: Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, memory loss, and impaired daily functioning. Despite significant research, AD remains incurable, highlighting the critical need for early diagnosis and intervention to improve patient outcomes. Timely detection plays a crucial role in managing the disease more effectively. Pretrained convolutional neural networks (CNNs) trained on large-scale datasets, such as ImageNet, have been employed for AD classification, providing a head start for developing more accurate models.

Methods: This paper proposes a novel hybrid deep learning approach that combines the strengths of two specific pretrained architectures. The proposed model enhances the representation of AD-related patterns by leveraging the feature extraction capabilities of both networks. We validated this model using a large dataset of MRI images from AD patients. Performance was evaluated in terms of classification accuracy and robustness against noise, and the results were compared to several commonly used models in AD detection.

Results: The proposed hybrid model demonstrated significant performance improvements over individual models, achieving an accuracy classification rate of 99.85%. Comparative analysis with other models further revealed the superiority of the new architecture, particularly in terms of classification rate and resistance to noise interference.

Discussion: The high accuracy and robustness of the proposed hybrid model suggest its potential utility in early AD detection. By improving feature representation through the combination of two pretrained networks, this model could provide clinicians with a more reliable tool for early diagnosis and monitoring of AD progression. This approach holds promise for aiding in timely diagnoses and treatment decisions, contributing to better management of Alzheimer's disease.

前言阿尔茨海默病(AD)是一种进行性神经退行性疾病,以认知能力下降、记忆力减退和日常功能受损为特征。尽管开展了大量研究,但阿尔茨海默病仍无法治愈,这突出表明了早期诊断和干预以改善患者预后的迫切需要。及时发现对更有效地控制疾病起着至关重要的作用。在大规模数据集(如 ImageNet)上训练的预训练卷积神经网络(CNN)已被用于 AD 分类,为开发更精确的模型提供了一个良好的开端:本文提出了一种新型混合深度学习方法,它结合了两种特定预训练架构的优势。通过利用这两种网络的特征提取能力,所提出的模型增强了对注意力缺失症相关模式的表示。我们使用来自 AD 患者的大型 MRI 图像数据集对该模型进行了验证。我们从分类准确性和对噪声的鲁棒性两个方面对其性能进行了评估,并将结果与一些常用的注意力缺失症检测模型进行了比较:结果:与单个模型相比,所提出的混合模型的性能有了显著提高,分类准确率达到 99.85%。与其他模型的对比分析进一步显示了新架构的优越性,尤其是在分类率和抗噪声干扰能力方面:讨论:所提出的混合模型的高准确率和鲁棒性表明,它在早期注意力缺失症检测中具有潜在的实用性。通过结合两个预训练网络来改进特征表示,该模型可以为临床医生提供更可靠的工具,用于早期诊断和监测注意力缺失症的进展。这种方法有望帮助及时做出诊断和治疗决定,为更好地管理阿尔茨海默病做出贡献。
{"title":"A combinatorial deep learning method for Alzheimer's disease classification-based merging pretrained networks.","authors":"Houmem Slimi, Ala Balti, Sabeur Abid, Mounir Sayadi","doi":"10.3389/fncom.2024.1444019","DOIUrl":"10.3389/fncom.2024.1444019","url":null,"abstract":"<p><strong>Introduction: </strong>Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, memory loss, and impaired daily functioning. Despite significant research, AD remains incurable, highlighting the critical need for early diagnosis and intervention to improve patient outcomes. Timely detection plays a crucial role in managing the disease more effectively. Pretrained convolutional neural networks (CNNs) trained on large-scale datasets, such as ImageNet, have been employed for AD classification, providing a head start for developing more accurate models.</p><p><strong>Methods: </strong>This paper proposes a novel hybrid deep learning approach that combines the strengths of two specific pretrained architectures. The proposed model enhances the representation of AD-related patterns by leveraging the feature extraction capabilities of both networks. We validated this model using a large dataset of MRI images from AD patients. Performance was evaluated in terms of classification accuracy and robustness against noise, and the results were compared to several commonly used models in AD detection.</p><p><strong>Results: </strong>The proposed hybrid model demonstrated significant performance improvements over individual models, achieving an accuracy classification rate of 99.85%. Comparative analysis with other models further revealed the superiority of the new architecture, particularly in terms of classification rate and resistance to noise interference.</p><p><strong>Discussion: </strong>The high accuracy and robustness of the proposed hybrid model suggest its potential utility in early AD detection. By improving feature representation through the combination of two pretrained networks, this model could provide clinicians with a more reliable tool for early diagnosis and monitoring of AD progression. This approach holds promise for aiding in timely diagnoses and treatment decisions, contributing to better management of Alzheimer's disease.</p>","PeriodicalId":12363,"journal":{"name":"Frontiers in Computational Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142557513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multi-scale asynchronous correlation and 2D convolutional autoencoder for adolescent health risk prediction with limited fMRI data. 利用有限的 fMRI 数据进行青少年健康风险预测的多尺度异步相关性和二维卷积自动编码器。
IF 2.1 4区 医学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2024-10-15 eCollection Date: 2024-01-01 DOI: 10.3389/fncom.2024.1478193
Di Gao, Guanghao Yang, Jiarun Shen, Fang Wu, Chao Ji

Introduction: Adolescence is a fundamental period of transformation, encompassing extensive physical, psychological, and behavioral changes. Effective health risk assessment during this stage is crucial for timely intervention, yet traditional methodologies often fail to accurately predict mental and behavioral health risks due to the intricacy of neural dynamics and the scarcity of quality-annotated fMRI datasets.

Methods: This study introduces an innovative deep learning-based framework for health risk assessment in adolescents by employing a combination of a two-dimensional convolutional autoencoder (2DCNN-AE) with multi-sequence learning and multi-scale asynchronous correlation information extraction techniques. This approach facilitates the intricate analysis of spatial and temporal features within fMRI data, aiming to enhance the accuracy of the risk assessment process.

Results: Upon examination using the Adolescent Risk Behavior (AHRB) dataset, which includes fMRI scans from 174 individuals aged 17-22, the proposed methodology exhibited a significant improvement over conventional models. It attained a precision of 83.116%, a recall of 84.784%, and an F1-score of 83.942%, surpassing standard benchmarks in most pertinent evaluative measures.

Discussion: The results underscore the superior performance of the deep learning-based approach in understanding and predicting health-related risks in adolescents. It underscores the value of this methodology in advancing the precision of health risk assessments, offering an enhanced tool for early detection and potential intervention strategies in this sensitive developmental stage.

引言青春期是一个基本的转变时期,包括广泛的生理、心理和行为变化。在这一阶段进行有效的健康风险评估对于及时干预至关重要,然而,由于神经动力学的复杂性和高质量标注的 fMRI 数据集的稀缺性,传统方法往往无法准确预测心理和行为健康风险:本研究采用二维卷积自动编码器(2DCNN-AE)与多序列学习和多尺度异步相关信息提取技术相结合的方法,为青少年健康风险评估引入了一种基于深度学习的创新框架。这种方法有助于对 fMRI 数据中的空间和时间特征进行复杂分析,从而提高风险评估过程的准确性:在使用青少年风险行为(AHRB)数据集(其中包括 174 名 17-22 岁个体的 fMRI 扫描)进行检验后,所提出的方法比传统模型有了显著改善。其精确度为 83.116%,召回率为 84.784%,F1 分数为 83.942%,在大多数相关评估指标上都超过了标准基准:结果表明,基于深度学习的方法在理解和预测青少年健康相关风险方面表现出色。讨论:研究结果表明,基于深度学习的方法在理解和预测青少年健康相关风险方面表现出色,并强调了该方法在提高健康风险评估的精确度方面的价值,为在这一敏感的发展阶段进行早期检测和制定潜在干预策略提供了更先进的工具。
{"title":"Multi-scale asynchronous correlation and 2D convolutional autoencoder for adolescent health risk prediction with limited fMRI data.","authors":"Di Gao, Guanghao Yang, Jiarun Shen, Fang Wu, Chao Ji","doi":"10.3389/fncom.2024.1478193","DOIUrl":"https://doi.org/10.3389/fncom.2024.1478193","url":null,"abstract":"<p><strong>Introduction: </strong>Adolescence is a fundamental period of transformation, encompassing extensive physical, psychological, and behavioral changes. Effective health risk assessment during this stage is crucial for timely intervention, yet traditional methodologies often fail to accurately predict mental and behavioral health risks due to the intricacy of neural dynamics and the scarcity of quality-annotated fMRI datasets.</p><p><strong>Methods: </strong>This study introduces an innovative deep learning-based framework for health risk assessment in adolescents by employing a combination of a two-dimensional convolutional autoencoder (2DCNN-AE) with multi-sequence learning and multi-scale asynchronous correlation information extraction techniques. This approach facilitates the intricate analysis of spatial and temporal features within fMRI data, aiming to enhance the accuracy of the risk assessment process.</p><p><strong>Results: </strong>Upon examination using the Adolescent Risk Behavior (AHRB) dataset, which includes fMRI scans from 174 individuals aged 17-22, the proposed methodology exhibited a significant improvement over conventional models. It attained a precision of 83.116%, a recall of 84.784%, and an F1-score of 83.942%, surpassing standard benchmarks in most pertinent evaluative measures.</p><p><strong>Discussion: </strong>The results underscore the superior performance of the deep learning-based approach in understanding and predicting health-related risks in adolescents. It underscores the value of this methodology in advancing the precision of health risk assessments, offering an enhanced tool for early detection and potential intervention strategies in this sensitive developmental stage.</p>","PeriodicalId":12363,"journal":{"name":"Frontiers in Computational Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11518741/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimizing extubation success: a comparative analysis of time series algorithms and activation functions. 优化拔管成功率:时间序列算法和激活函数的比较分析。
IF 2.1 4区 医学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2024-10-04 eCollection Date: 2024-01-01 DOI: 10.3389/fncom.2024.1456771
Kuo-Yang Huang, Ching-Hsiung Lin, Shu-Hua Chi, Ying-Lin Hsu, Jia-Lang Xu

Background: The success and failure of extubation of patients with acute respiratory failure is a very important issue for clinicians, and the failure of the ventilator often leads to possible complications, which in turn leads to a lot of doubts about the medical treatment in the minds of the people, so in order to increase the success of extubation success of the doctors to prevent the possible complications, the present study compared different time series algorithms and different activation functions for the training and prediction of extubation success or failure models.

Methods: This study compared different time series algorithms and different activation functions for training and predicting the success or failure of the extubation model.

Results: The results of this study using four validation methods show that the GRU model and Tanh's model have a better predictive model for predicting the success or failure of the extubation and better predictive result of 94.44% can be obtained using Holdout cross-validation validation method.

Conclusion: This study proposes a prediction method using GRU on the topic of extubation, and it can provide the doctors with the clinical application of extubation to give advice for reference.

背景:对于临床医生来说,急性呼吸衰竭患者的拔管成功与否是一个非常重要的问题,而呼吸机的失灵往往会导致可能出现的并发症,进而导致人们心中对医疗产生诸多疑虑,因此为了提高医生的拔管成功率,防止可能出现的并发症,本研究比较了不同时间序列算法和不同激活函数对拔管成功或失败模型的训练和预测:本研究比较了用于训练和预测拔管成功或失败模型的不同时间序列算法和不同激活函数:本研究使用四种验证方法的结果表明,GRU 模型和 Tanh's 模型在预测拔管成败方面具有较好的预测模型,使用 Holdout 交叉验证验证方法可获得 94.44% 的较好预测结果:本研究提出了一种以拔管为主题的GRU预测方法,可为医生提供拔管的临床应用建议,以供参考。
{"title":"Optimizing extubation success: a comparative analysis of time series algorithms and activation functions.","authors":"Kuo-Yang Huang, Ching-Hsiung Lin, Shu-Hua Chi, Ying-Lin Hsu, Jia-Lang Xu","doi":"10.3389/fncom.2024.1456771","DOIUrl":"10.3389/fncom.2024.1456771","url":null,"abstract":"<p><strong>Background: </strong>The success and failure of extubation of patients with acute respiratory failure is a very important issue for clinicians, and the failure of the ventilator often leads to possible complications, which in turn leads to a lot of doubts about the medical treatment in the minds of the people, so in order to increase the success of extubation success of the doctors to prevent the possible complications, the present study compared different time series algorithms and different activation functions for the training and prediction of extubation success or failure models.</p><p><strong>Methods: </strong>This study compared different time series algorithms and different activation functions for training and predicting the success or failure of the extubation model.</p><p><strong>Results: </strong>The results of this study using four validation methods show that the GRU model and Tanh's model have a better predictive model for predicting the success or failure of the extubation and better predictive result of 94.44% can be obtained using Holdout cross-validation validation method.</p><p><strong>Conclusion: </strong>This study proposes a prediction method using GRU on the topic of extubation, and it can provide the doctors with the clinical application of extubation to give advice for reference.</p>","PeriodicalId":12363,"journal":{"name":"Frontiers in Computational Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11486667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Decoding the application of deep learning in neuroscience: a bibliometric analysis. 解码深度学习在神经科学中的应用:文献计量分析。
IF 2.1 4区 医学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2024-10-04 eCollection Date: 2024-01-01 DOI: 10.3389/fncom.2024.1402689
Yin Li, Zilong Zhong

The application of deep learning in neuroscience holds unprecedented potential for unraveling the complex dynamics of the brain. Our bibliometric analysis, spanning from 2012 to 2023, delves into the integration of deep learning in neuroscience, shedding light on the evolutionary trends and identifying pivotal research hotspots. Through the examination of 421 articles, this study unveils a significant growth in interdisciplinary research, marked by the burgeoning application of deep learning techniques in understanding neural mechanisms and addressing neurological disorders. Central to our findings is the critical role of classification algorithms, models, and neural networks in advancing neuroscience, highlighting their efficacy in interpreting complex neural data, simulating brain functions, and translating theoretical insights into practical diagnostics and therapeutic interventions. Additionally, our analysis delineates a thematic evolution, showcasing a shift from foundational methodologies toward more specialized and nuanced approaches, particularly in areas like EEG analysis and convolutional neural networks. This evolution reflects the field's maturation and its adaptation to technological advancements. The study further emphasizes the importance of interdisciplinary collaborations and the adoption of cutting-edge technologies to foster innovation in decoding the cerebral code. The current study provides a strategic roadmap for future explorations, urging the scientific community toward areas ripe for breakthrough discoveries and practical applications. This analysis not only charts the past and present landscape of deep learning in neuroscience but also illuminates pathways for future research, underscoring the transformative impact of deep learning on our understanding of the brain.

深度学习在神经科学中的应用为揭示大脑的复杂动力学提供了前所未有的潜力。我们的文献计量分析跨越 2012 年至 2023 年,深入探讨了深度学习与神经科学的结合,揭示了演变趋势,并确定了关键的研究热点。通过对 421 篇文章的研究,本研究揭示了跨学科研究的显著增长,其标志是深度学习技术在理解神经机制和解决神经系统疾病方面的蓬勃应用。我们研究结果的核心是分类算法、模型和神经网络在推动神经科学发展方面的关键作用,突出了它们在解释复杂神经数据、模拟大脑功能以及将理论见解转化为实际诊断和治疗干预措施方面的功效。此外,我们的分析还勾勒出一个主题演变过程,展示了从基础方法到更专业、更细致的方法的转变,尤其是在脑电图分析和卷积神经网络等领域。这种演变反映了该领域的成熟及其对技术进步的适应。研究进一步强调了跨学科合作和采用尖端技术的重要性,以促进解码大脑密码的创新。当前的研究为未来的探索提供了一个战略路线图,敦促科学界朝着突破性发现和实际应用成熟的领域迈进。这项分析不仅描绘了神经科学领域深度学习的过去和现在,还为未来研究指明了道路,强调了深度学习对我们理解大脑的变革性影响。
{"title":"Decoding the application of deep learning in neuroscience: a bibliometric analysis.","authors":"Yin Li, Zilong Zhong","doi":"10.3389/fncom.2024.1402689","DOIUrl":"10.3389/fncom.2024.1402689","url":null,"abstract":"<p><p>The application of deep learning in neuroscience holds unprecedented potential for unraveling the complex dynamics of the brain. Our bibliometric analysis, spanning from 2012 to 2023, delves into the integration of deep learning in neuroscience, shedding light on the evolutionary trends and identifying pivotal research hotspots. Through the examination of 421 articles, this study unveils a significant growth in interdisciplinary research, marked by the burgeoning application of deep learning techniques in understanding neural mechanisms and addressing neurological disorders. Central to our findings is the critical role of classification algorithms, models, and neural networks in advancing neuroscience, highlighting their efficacy in interpreting complex neural data, simulating brain functions, and translating theoretical insights into practical diagnostics and therapeutic interventions. Additionally, our analysis delineates a thematic evolution, showcasing a shift from foundational methodologies toward more specialized and nuanced approaches, particularly in areas like EEG analysis and convolutional neural networks. This evolution reflects the field's maturation and its adaptation to technological advancements. The study further emphasizes the importance of interdisciplinary collaborations and the adoption of cutting-edge technologies to foster innovation in decoding the cerebral code. The current study provides a strategic roadmap for future explorations, urging the scientific community toward areas ripe for breakthrough discoveries and practical applications. This analysis not only charts the past and present landscape of deep learning in neuroscience but also illuminates pathways for future research, underscoring the transformative impact of deep learning on our understanding of the brain.</p>","PeriodicalId":12363,"journal":{"name":"Frontiers in Computational Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11486706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: Understanding and bridging the gap between neuromorphic computing and machine learning, volume II. 社论:理解和弥合神经形态计算与机器学习之间的差距》,第二卷。
IF 2.1 4区 医学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2024-10-03 eCollection Date: 2024-01-01 DOI: 10.3389/fncom.2024.1455530
Lei Deng, Huajin Tang, Kaushik Roy
{"title":"Editorial: Understanding and bridging the gap between neuromorphic computing and machine learning, volume II.","authors":"Lei Deng, Huajin Tang, Kaushik Roy","doi":"10.3389/fncom.2024.1455530","DOIUrl":"https://doi.org/10.3389/fncom.2024.1455530","url":null,"abstract":"","PeriodicalId":12363,"journal":{"name":"Frontiers in Computational Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11484035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multi-label remote sensing classification with self-supervised gated multi-modal transformers. 利用自监督门控多模式转换器进行多标签遥感分类。
IF 2.1 4区 医学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2024-09-24 eCollection Date: 2024-01-01 DOI: 10.3389/fncom.2024.1404623
Na Liu, Ye Yuan, Guodong Wu, Sai Zhang, Jie Leng, Lihong Wan

Introduction: With the great success of Transformers in the field of machine learning, it is also gradually attracting widespread interest in the field of remote sensing (RS). However, the research in the field of remote sensing has been hampered by the lack of large labeled data sets and the inconsistency of data modes caused by the diversity of RS platforms. With the rise of self-supervised learning (SSL) algorithms in recent years, RS researchers began to pay attention to the application of "pre-training and fine-tuning" paradigm in RS. However, there are few researches on multi-modal data fusion in remote sensing field. Most of them choose to use only one of the modal data or simply splice multiple modal data roughly.

Method: In order to study a more efficient multi-modal data fusion scheme, we propose a multi-modal fusion mechanism based on gated unit control (MGSViT). In this paper, we pretrain the ViT model based on BigEarthNet dataset by combining two commonly used SSL algorithms, and propose an intra-modal and inter-modal gated fusion unit for feature learning by combining multispectral (MS) and synthetic aperture radar (SAR). Our method can effectively combine different modal data to extract key feature information.

Results and discussion: After fine-tuning and comparison experiments, we outperform the most advanced algorithms in all downstream classification tasks. The validity of our proposed method is verified.

导言:随着变形金刚在机器学习领域的巨大成功,它也逐渐引起了遥感(RS)领域的广泛关注。然而,遥感领域的研究一直受制于缺乏大型标注数据集以及遥感平台多样性导致的数据模式不一致。近年来,随着自监督学习(SSL)算法的兴起,RS 研究人员开始关注 "预训练和微调 "范式在 RS 中的应用。然而,遥感领域的多模态数据融合研究还很少。他们大多选择只使用其中一种模态数据或简单地将多种模态数据粗略拼接的方法:为了研究一种更有效的多模态数据融合方案,我们提出了一种基于门控单元控制的多模态融合机制(MGSViT)。本文结合两种常用的 SSL 算法,基于 BigEarthNet 数据集对 ViT 模型进行预训练,并结合多光谱(MS)和合成孔径雷达(SAR),提出了用于特征学习的模内和模间门控融合单元。我们的方法可以有效地结合不同模态数据来提取关键特征信息:经过微调和对比实验,我们在所有下游分类任务中的表现都优于最先进的算法。我们提出的方法的有效性得到了验证。
{"title":"Multi-label remote sensing classification with self-supervised gated multi-modal transformers.","authors":"Na Liu, Ye Yuan, Guodong Wu, Sai Zhang, Jie Leng, Lihong Wan","doi":"10.3389/fncom.2024.1404623","DOIUrl":"https://doi.org/10.3389/fncom.2024.1404623","url":null,"abstract":"<p><strong>Introduction: </strong>With the great success of Transformers in the field of machine learning, it is also gradually attracting widespread interest in the field of remote sensing (RS). However, the research in the field of remote sensing has been hampered by the lack of large labeled data sets and the inconsistency of data modes caused by the diversity of RS platforms. With the rise of self-supervised learning (SSL) algorithms in recent years, RS researchers began to pay attention to the application of \"pre-training and fine-tuning\" paradigm in RS. However, there are few researches on multi-modal data fusion in remote sensing field. Most of them choose to use only one of the modal data or simply splice multiple modal data roughly.</p><p><strong>Method: </strong>In order to study a more efficient multi-modal data fusion scheme, we propose a multi-modal fusion mechanism based on gated unit control (MGSViT). In this paper, we pretrain the ViT model based on BigEarthNet dataset by combining two commonly used SSL algorithms, and propose an intra-modal and inter-modal gated fusion unit for feature learning by combining multispectral (MS) and synthetic aperture radar (SAR). Our method can effectively combine different modal data to extract key feature information.</p><p><strong>Results and discussion: </strong>After fine-tuning and comparison experiments, we outperform the most advanced algorithms in all downstream classification tasks. The validity of our proposed method is verified.</p>","PeriodicalId":12363,"journal":{"name":"Frontiers in Computational Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11458396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analyzing top-down visual attention in the context of gamma oscillations: a layer- dependent network-of- networks approach. 在伽马振荡背景下分析自上而下的视觉注意力:一种依赖层的网络方法。
IF 2.1 4区 医学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2024-09-23 eCollection Date: 2024-01-01 DOI: 10.3389/fncom.2024.1439632
Tianyi Zheng, Masato Sugino, Yasuhiko Jimbo, G Bard Ermentrout, Kiyoshi Kotani

Top-down visual attention is a fundamental cognitive process that allows individuals to selectively attend to salient visual stimuli in the environment. Recent empirical findings have revealed that gamma oscillations participate in the modulation of visual attention. However, computational studies face challenges when analyzing the attentional process in the context of gamma oscillation due to the unstable nature of gamma oscillations and the complexity induced by the layered fashion in the visual cortex. In this study, we propose a layer-dependent network-of-networks approach to analyze such attention with gamma oscillations. The model is validated by reproducing empirical findings on orientation preference and the enhancement of neuronal response due to top-down attention. We perform parameter plane analysis to classify neuronal responses into several patterns and find that the neuronal response to sensory and attention signals was modulated by the heterogeneity of the neuronal population. Furthermore, we revealed a counter-intuitive scenario that the excitatory populations in layer 2/3 and layer 5 exhibit opposite responses to the attentional input. By modification of the original model, we confirmed layer 6 plays an indispensable role in such cases. Our findings uncover the layer-dependent dynamics in the cortical processing of visual attention and open up new possibilities for further research on layer-dependent properties in the cerebral cortex.

自上而下的视觉注意是一种基本的认知过程,它能让人有选择地注意环境中的显著视觉刺激。最近的实证研究发现,伽马振荡参与了视觉注意力的调节。然而,由于伽马振荡的不稳定性和视觉皮层分层方式的复杂性,计算研究在分析伽马振荡背景下的注意过程时面临挑战。在本研究中,我们提出了一种层依赖网络(network-of-networks)方法来分析伽马振荡下的注意力。该模型通过再现方位偏好和自上而下注意引起的神经元反应增强的经验发现得到了验证。我们进行了参数平面分析,将神经元反应分为几种模式,并发现神经元对感觉和注意力信号的反应受神经元群异质性的调节。此外,我们还发现了一种与直觉相反的情况,即第 2/3 层和第 5 层的兴奋神经元群对注意输入的反应相反。通过修改原始模型,我们证实第 6 层在这种情况下发挥着不可或缺的作用。我们的发现揭示了大脑皮层处理视觉注意力过程中的层依赖动态,为进一步研究大脑皮层的层依赖特性提供了新的可能性。
{"title":"Analyzing top-down visual attention in the context of gamma oscillations: a layer- dependent network-of- networks approach.","authors":"Tianyi Zheng, Masato Sugino, Yasuhiko Jimbo, G Bard Ermentrout, Kiyoshi Kotani","doi":"10.3389/fncom.2024.1439632","DOIUrl":"https://doi.org/10.3389/fncom.2024.1439632","url":null,"abstract":"<p><p>Top-down visual attention is a fundamental cognitive process that allows individuals to selectively attend to salient visual stimuli in the environment. Recent empirical findings have revealed that gamma oscillations participate in the modulation of visual attention. However, computational studies face challenges when analyzing the attentional process in the context of gamma oscillation due to the unstable nature of gamma oscillations and the complexity induced by the layered fashion in the visual cortex. In this study, we propose a layer-dependent network-of-networks approach to analyze such attention with gamma oscillations. The model is validated by reproducing empirical findings on orientation preference and the enhancement of neuronal response due to top-down attention. We perform parameter plane analysis to classify neuronal responses into several patterns and find that the neuronal response to sensory and attention signals was modulated by the heterogeneity of the neuronal population. Furthermore, we revealed a counter-intuitive scenario that the excitatory populations in layer 2/3 and layer 5 exhibit opposite responses to the attentional input. By modification of the original model, we confirmed layer 6 plays an indispensable role in such cases. Our findings uncover the layer-dependent dynamics in the cortical processing of visual attention and open up new possibilities for further research on layer-dependent properties in the cerebral cortex.</p>","PeriodicalId":12363,"journal":{"name":"Frontiers in Computational Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11456483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142389238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dynamical predictive coding with reservoir computing performs noise-robust multi-sensory speech recognition. 动态预测编码与蓄水池计算实现了噪声稳健的多感官语音识别。
IF 2.1 4区 医学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2024-09-23 eCollection Date: 2024-01-01 DOI: 10.3389/fncom.2024.1464603
Yoshihiro Yonemura, Yuichi Katori

Multi-sensory integration is a perceptual process through which the brain synthesizes a unified perception by integrating inputs from multiple sensory modalities. A key issue is understanding how the brain performs multi-sensory integrations using a common neural basis in the cortex. A cortical model based on reservoir computing has been proposed to elucidate the role of recurrent connectivity among cortical neurons in this process. Reservoir computing is well-suited for time series processing, such as speech recognition. This inquiry focuses on extending a reservoir computing-based cortical model to encompass multi-sensory integration within the cortex. This research introduces a dynamical model of multi-sensory speech recognition, leveraging predictive coding combined with reservoir computing. Predictive coding offers a framework for the hierarchical structure of the cortex. The model integrates reliability weighting, derived from the computational theory of multi-sensory integration, to adapt to multi-sensory time series processing. The model addresses a multi-sensory speech recognition task, necessitating the management of complex time series. We observed that the reservoir effectively recognizes speech by extracting time-contextual information and weighting sensory inputs according to sensory noise. These findings indicate that the dynamic properties of recurrent networks are applicable to multi-sensory time series processing, positioning reservoir computing as a suitable model for multi-sensory integration.

多感觉统合是一个感知过程,大脑通过整合多种感觉模式的输入来合成统一的感知。一个关键问题是了解大脑如何利用皮层中的共同神经基础进行多感官整合。有人提出了一个基于储库计算的大脑皮层模型,以阐明大脑皮层神经元之间的循环连接在这一过程中的作用。水库计算非常适合语音识别等时间序列处理。本研究的重点是扩展基于水库计算的皮层模型,以涵盖皮层内的多感官整合。这项研究引入了一个多感官语音识别动态模型,利用预测编码与水库计算相结合。预测编码为大脑皮层的层次结构提供了一个框架。该模型整合了从多感官整合计算理论中得出的可靠性加权,以适应多感官时间序列处理。该模型针对的是需要管理复杂时间序列的多感官语音识别任务。我们观察到,通过提取时间上下文信息并根据感官噪声对感官输入进行加权,水库能有效识别语音。这些研究结果表明,递归网络的动态特性适用于多感官时间序列处理,从而将水库计算定位为多感官整合的合适模型。
{"title":"Dynamical predictive coding with reservoir computing performs noise-robust multi-sensory speech recognition.","authors":"Yoshihiro Yonemura, Yuichi Katori","doi":"10.3389/fncom.2024.1464603","DOIUrl":"https://doi.org/10.3389/fncom.2024.1464603","url":null,"abstract":"<p><p>Multi-sensory integration is a perceptual process through which the brain synthesizes a unified perception by integrating inputs from multiple sensory modalities. A key issue is understanding how the brain performs multi-sensory integrations using a common neural basis in the cortex. A cortical model based on reservoir computing has been proposed to elucidate the role of recurrent connectivity among cortical neurons in this process. Reservoir computing is well-suited for time series processing, such as speech recognition. This inquiry focuses on extending a reservoir computing-based cortical model to encompass multi-sensory integration within the cortex. This research introduces a dynamical model of multi-sensory speech recognition, leveraging predictive coding combined with reservoir computing. Predictive coding offers a framework for the hierarchical structure of the cortex. The model integrates reliability weighting, derived from the computational theory of multi-sensory integration, to adapt to multi-sensory time series processing. The model addresses a multi-sensory speech recognition task, necessitating the management of complex time series. We observed that the reservoir effectively recognizes speech by extracting time-contextual information and weighting sensory inputs according to sensory noise. These findings indicate that the dynamic properties of recurrent networks are applicable to multi-sensory time series processing, positioning reservoir computing as a suitable model for multi-sensory integration.</p>","PeriodicalId":12363,"journal":{"name":"Frontiers in Computational Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11456454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142389239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep learning-based Alzheimer's disease detection: reproducibility and the effect of modeling choices. 基于深度学习的阿尔茨海默病检测:可重复性和建模选择的影响。
IF 2.1 4区 医学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2024-09-20 eCollection Date: 2024-01-01 DOI: 10.3389/fncom.2024.1360095
Rosanna Turrisi, Alessandro Verri, Annalisa Barla

Introduction: Machine Learning (ML) has emerged as a promising approach in healthcare, outperforming traditional statistical techniques. However, to establish ML as a reliable tool in clinical practice, adherence to best practices in data handling, and modeling design and assessment is crucial. In this work, we summarize and strictly adhere to such practices to ensure reproducible and reliable ML. Specifically, we focus on Alzheimer's Disease (AD) detection, a challenging problem in healthcare. Additionally, we investigate the impact of modeling choices, including different data augmentation techniques and model complexity, on overall performance.

Methods: We utilize Magnetic Resonance Imaging (MRI) data from the ADNI corpus to address a binary classification problem using 3D Convolutional Neural Networks (CNNs). Data processing and modeling are specifically tailored to address data scarcity and minimize computational overhead. Within this framework, we train 15 predictive models, considering three different data augmentation strategies and five distinct 3D CNN architectures with varying convolutional layers counts. The augmentation strategies involve affine transformations, such as zoom, shift, and rotation, applied either concurrently or separately.

Results: The combined effect of data augmentation and model complexity results in up to 10% variation in prediction accuracy. Notably, when affine transformation are applied separately, the model achieves higher accuracy, regardless the chosen architecture. Across all strategies, the model accuracy exhibits a concave behavior as the number of convolutional layers increases, peaking at an intermediate value. The best model reaches excellent performance both on the internal and additional external testing set.

Discussions: Our work underscores the critical importance of adhering to rigorous experimental practices in the field of ML applied to healthcare. The results clearly demonstrate how data augmentation and model depth-often overlooked factors- can dramatically impact final performance if not thoroughly investigated. This highlights both the necessity of exploring neglected modeling aspects and the need to comprehensively report all modeling choices to ensure reproducibility and facilitate meaningful comparisons across studies.

简介:机器学习(ML)已成为医疗保健领域一种前景广阔的方法,其性能优于传统的统计技术。然而,要将机器学习作为临床实践中的可靠工具,遵守数据处理、建模设计和评估方面的最佳实践至关重要。在这项工作中,我们总结并严格遵守这些做法,以确保 ML 的可重复性和可靠性。具体来说,我们将重点放在阿尔茨海默病(AD)的检测上,这是医疗保健领域的一个挑战性问题。此外,我们还研究了建模选择(包括不同的数据增强技术和模型复杂性)对总体性能的影响:我们利用 ADNI 语料库中的磁共振成像(MRI)数据,使用三维卷积神经网络(CNN)解决二元分类问题。数据处理和建模是专门为解决数据稀缺和最大限度减少计算开销而定制的。在此框架内,我们训练了 15 个预测模型,考虑了三种不同的数据增强策略和五种具有不同卷积层数的三维卷积神经网络架构。增强策略涉及仿射变换,如缩放、移位和旋转,可同时或单独应用:结果:数据增强和模型复杂性的综合影响导致预测准确率的变化高达 10%。值得注意的是,当仿射变换单独应用时,无论选择何种架构,模型都能达到更高的准确度。在所有策略中,随着卷积层数的增加,模型的准确性呈现出凹凸行为,并在中间值达到峰值。最佳模型在内部测试集和额外的外部测试集上都达到了极佳的性能:我们的工作强调了在应用于医疗保健的人工智能领域坚持严格实验实践的重要性。研究结果清楚地表明了数据扩充和模型深度--这些经常被忽视的因素--如果不进行深入研究,会如何极大地影响最终性能。这既强调了探索被忽视的建模方面的必要性,也强调了全面报告所有建模选择的必要性,以确保可重复性并促进不同研究之间进行有意义的比较。
{"title":"Deep learning-based Alzheimer's disease detection: reproducibility and the effect of modeling choices.","authors":"Rosanna Turrisi, Alessandro Verri, Annalisa Barla","doi":"10.3389/fncom.2024.1360095","DOIUrl":"10.3389/fncom.2024.1360095","url":null,"abstract":"<p><strong>Introduction: </strong>Machine Learning (ML) has emerged as a promising approach in healthcare, outperforming traditional statistical techniques. However, to establish ML as a reliable tool in clinical practice, adherence to best practices in <i>data handling</i>, and <i>modeling design and assessment</i> is crucial. In this work, we summarize and strictly adhere to such practices to ensure reproducible and reliable ML. Specifically, we focus on Alzheimer's Disease (AD) detection, a challenging problem in healthcare. Additionally, we investigate the impact of modeling choices, including different data augmentation techniques and model complexity, on overall performance.</p><p><strong>Methods: </strong>We utilize Magnetic Resonance Imaging (MRI) data from the ADNI corpus to address a binary classification problem using 3D Convolutional Neural Networks (CNNs). Data processing and modeling are specifically tailored to address data scarcity and minimize computational overhead. Within this framework, we train 15 predictive models, considering three different data augmentation strategies and five distinct 3D CNN architectures with varying convolutional layers counts. The augmentation strategies involve affine transformations, such as <i>zoom, shift</i>, and <i>rotation</i>, applied either concurrently or separately.</p><p><strong>Results: </strong>The combined effect of data augmentation and model complexity results in up to 10% variation in prediction accuracy. Notably, when affine transformation are applied separately, the model achieves higher accuracy, regardless the chosen architecture. Across all strategies, the model accuracy exhibits a concave behavior as the number of convolutional layers increases, peaking at an intermediate value. The best model reaches excellent performance both on the internal and additional external testing set.</p><p><strong>Discussions: </strong>Our work underscores the critical importance of adhering to rigorous experimental practices in the field of ML applied to healthcare. The results clearly demonstrate how data augmentation and model depth-often overlooked factors- can dramatically impact final performance if not thoroughly investigated. This highlights both the necessity of exploring neglected modeling aspects and the need to comprehensively report all modeling choices to ensure reproducibility and facilitate meaningful comparisons across studies.</p>","PeriodicalId":12363,"journal":{"name":"Frontiers in Computational Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11451303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142380448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electroencephalogram-based adaptive closed-loop brain-computer interface in neurorehabilitation: a review. 基于脑电图的自适应闭环脑机接口在神经康复中的应用:综述。
IF 2.1 4区 医学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2024-09-20 eCollection Date: 2024-01-01 DOI: 10.3389/fncom.2024.1431815
Wenjie Jin, XinXin Zhu, Lifeng Qian, Cunshu Wu, Fan Yang, Daowei Zhan, Zhaoyin Kang, Kaitao Luo, Dianhuai Meng, Guangxu Xu

Brain-computer interfaces (BCIs) represent a groundbreaking approach to enabling direct communication for individuals with severe motor impairments, circumventing traditional neural and muscular pathways. Among the diverse array of BCI technologies, electroencephalogram (EEG)-based systems are particularly favored due to their non-invasive nature, user-friendly operation, and cost-effectiveness. Recent advancements have facilitated the development of adaptive bidirectional closed-loop BCIs, which dynamically adjust to users' brain activity, thereby enhancing responsiveness and efficacy in neurorehabilitation. These systems support real-time modulation and continuous feedback, fostering personalized therapeutic interventions that align with users' neural and behavioral responses. By incorporating machine learning algorithms, these BCIs optimize user interaction and promote recovery outcomes through mechanisms of activity-dependent neuroplasticity. This paper reviews the current landscape of EEG-based adaptive bidirectional closed-loop BCIs, examining their applications in the recovery of motor and sensory functions, as well as the challenges encountered in practical implementation. The findings underscore the potential of these technologies to significantly enhance patients' quality of life and social interaction, while also identifying critical areas for future research aimed at improving system adaptability and performance. As advancements in artificial intelligence continue, the evolution of sophisticated BCI systems holds promise for transforming neurorehabilitation and expanding applications across various domains.

脑机接口(BCI)是一种突破性的方法,它可以绕过传统的神经和肌肉通路,让有严重运动障碍的人直接进行交流。在种类繁多的 BCI 技术中,基于脑电图(EEG)的系统因其非侵入性、操作简便和成本效益高而备受青睐。最近的进步促进了自适应双向闭环生物识别(BCI)技术的发展,该技术可根据用户的大脑活动进行动态调整,从而提高神经康复的响应速度和疗效。这些系统支持实时调节和持续反馈,可根据用户的神经和行为反应进行个性化治疗干预。通过结合机器学习算法,这些 BCI 可优化用户互动,并通过依赖活动的神经可塑性机制促进康复效果。本文回顾了基于脑电图的自适应双向闭环 BCI 目前的发展状况,研究了它们在运动和感觉功能恢复方面的应用,以及在实际应用中遇到的挑战。研究结果强调了这些技术在显著提高患者生活质量和社会交往方面的潜力,同时也指出了未来研究的关键领域,旨在提高系统的适应性和性能。随着人工智能的不断进步,先进的生物识别(BCI)系统有望改变神经康复的现状,并扩大在各个领域的应用。
{"title":"Electroencephalogram-based adaptive closed-loop brain-computer interface in neurorehabilitation: a review.","authors":"Wenjie Jin, XinXin Zhu, Lifeng Qian, Cunshu Wu, Fan Yang, Daowei Zhan, Zhaoyin Kang, Kaitao Luo, Dianhuai Meng, Guangxu Xu","doi":"10.3389/fncom.2024.1431815","DOIUrl":"10.3389/fncom.2024.1431815","url":null,"abstract":"<p><p>Brain-computer interfaces (BCIs) represent a groundbreaking approach to enabling direct communication for individuals with severe motor impairments, circumventing traditional neural and muscular pathways. Among the diverse array of BCI technologies, electroencephalogram (EEG)-based systems are particularly favored due to their non-invasive nature, user-friendly operation, and cost-effectiveness. Recent advancements have facilitated the development of adaptive bidirectional closed-loop BCIs, which dynamically adjust to users' brain activity, thereby enhancing responsiveness and efficacy in neurorehabilitation. These systems support real-time modulation and continuous feedback, fostering personalized therapeutic interventions that align with users' neural and behavioral responses. By incorporating machine learning algorithms, these BCIs optimize user interaction and promote recovery outcomes through mechanisms of activity-dependent neuroplasticity. This paper reviews the current landscape of EEG-based adaptive bidirectional closed-loop BCIs, examining their applications in the recovery of motor and sensory functions, as well as the challenges encountered in practical implementation. The findings underscore the potential of these technologies to significantly enhance patients' quality of life and social interaction, while also identifying critical areas for future research aimed at improving system adaptability and performance. As advancements in artificial intelligence continue, the evolution of sophisticated BCI systems holds promise for transforming neurorehabilitation and expanding applications across various domains.</p>","PeriodicalId":12363,"journal":{"name":"Frontiers in Computational Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11449715/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142380449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Frontiers in Computational Neuroscience
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1