Von willebrand disease and gastrointestinal bleeding: case presentation

Ariel Raúl Aragón Abrantes, Danelis Hernández Aguiar, Nidia Crespo Toledo, Carmen Ulloa Olivera
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Abstract

Introduction: Von Willebrand diseases is a hereditary bleeding disorder caused by a quantitative or qualitative deficiency of von Willebrand factor, characterized by light mucocutaneous bleeding, although other bleeding such as gastrointestinal and joint bleeding may occur in severely affected patients. It treatment is fundamentally based on replacement therapy and the use of desmoprecin. Objective: Describe the characteristics and clinical evolution of a patient who presented upper gastrointestinal bleeding as a form of presentation of von Willebrand disease. Conclusions: von Willebrand diseases hould be suspected in patients with abnormal bleeding symptoms without apparent causes.
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冯-威廉氏病与消化道出血:病例介绍
简介冯-维勒布兰德病是一种遗传性出血性疾病,由冯-维勒布兰德因子定量或定性缺乏引起,以轻度皮肤粘膜出血为特征,但严重患者也可能出现其他出血,如胃肠道出血和关节出血。该病的治疗主要依靠替代疗法和去甲斑蝥素。目的描述一名以上消化道出血为表现形式的von Willebrand病患者的特征和临床演变。结论:对于无明显诱因而出现异常出血症状的患者,应怀疑冯-威廉氏病。
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