Long-term durability of thermoplastic elastomer containing antiviral additives for mobility applications

Zeynep Iyigundogdu, Rachel Couvreur, Sandeep Tamrakar, Jaewon Yoon, Basak Basar, Osman G. Ersoy, Fikrettin Sahin, Deborah Mielewski, Alper Kiziltas
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Abstract

In the mobility market, there is a demand from customers for antimicrobial protection. As a result, the market has grown considerably to provide antiviral and antimicrobial polymers and coatings. This study examines how the efficacy of a non-commercial antimicrobial thermoplastic elastomer will change over the life of the application. Using an example application of an electric scooter handlebar grip, durability requirements were identified, and antiviral efficacy (exceeding a log value of 3 or >99.9 microbial growth reduction) was compared before and after testing. A scooter handlebar grip was selected as the ideal example application as it was a high-touch surface, with several different riders. During the start of this study, scooter companies were encouraging their riders to disinfect scooter handlebars before riding, use hand sanitizer, and wear gloves. If the handlebar grip could be antimicrobial, then they could eliminate these steps and provide a safe ride for the users. In order to simulate long-term durability, UV exposure, temperature, humidity, artificial sweat, sunscreen, insect repellent, and abrasion tests were performed and evaluated in terms of antiviral activity. Accelerated weathering reduced the virucidal activity of the sample versus unexposed antiviral thermoplastic elastomer (TPE). However, the efficacy increased with contact time from 90% to 96.83% at 30 and 120 min, respectively. Abrasion resistance of antiviral TPE showed a volume loss of 66 mm3 compared to control samples of 83 mm3. The antiviral TPE sample exhibited slightly lower efficacy compared to the control after exposure to the artificial sweat (99.43% vs. 99.95%). Additionally, a skin tolerance test conducted on rabbits showed that antiviral TPE was not an irritant and showed no dermal toxicity. The outcome of this study will lead to the development of long-term durable antimicrobial material for the transportation industry.

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含有抗病毒添加剂的热塑性弹性体在移动应用中的长期耐用性
在流动性市场,客户对抗菌保护有需求。因此,提供抗病毒和抗菌聚合物及涂层的市场已大幅增长。本研究探讨了非商业性抗菌热塑性弹性体的功效在应用寿命期间的变化情况。以电动滑板车手把的应用为例,确定了耐久性要求,并对测试前后的抗病毒功效(超过 3 的对数值或微生物生长减少 99.9)进行了比较。滑板车手把被选为理想的应用示例,因为它是一个高接触表面,有多个不同的骑手。在这项研究开始时,踏板车公司鼓励骑手在骑车前对踏板车把手进行消毒,使用洗手液,并戴上手套。如果手把可以抗菌,那么他们就可以省去这些步骤,为用户提供安全的骑行体验。为了模拟长期耐久性,进行了紫外线照射、温度、湿度、人工汗液、防晒霜、驱虫剂和磨损测试,并对抗病毒活性进行了评估。与未暴露的抗病毒热塑性弹性体(TPE)相比,加速风化降低了样品的杀病毒活性。然而,随着接触时间的延长,30 分钟和 120 分钟时的效力分别从 90% 提高到 96.83%。抗病毒热塑性弹性体的耐磨性显示,与对照样品 83 立方毫米的体积损失相比,抗病毒热塑性弹性体的体积损失为 66 立方毫米。与对照组相比,抗病毒 TPE 样品在接触人工汗液后的功效略低(99.43% 对 99.95%)。此外,对兔子进行的皮肤耐受性测试表明,抗病毒 TPE 没有刺激性,也没有皮肤毒性。这项研究的结果将有助于为运输业开发长期耐用的抗菌材料。
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