Modified capillary number to standardize droplet generation in suction-driven microfluidics

IF 2.3 4区 工程技术 Q2 INSTRUMENTS & INSTRUMENTATION Microfluidics and Nanofluidics Pub Date : 2024-03-22 DOI:10.1007/s10404-024-02714-2
Jatin Panwar, Rahul Roy
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Abstract

In droplet microfluidic devices with suction-based flow control, the microchannel geometry and suction pressure at the outlet govern the dynamic properties of the two phases that influence the droplet generation. Therefore, it is critical to understand the role of geometry along with suction pressure in the dynamics of droplet generation to develop a predictive model. We conducted a comprehensive characterization of droplet generation in a flow focusing device with varying control parameters. We used these results to formulate a scaling argument and propose a governing parameter, called as modified capillary number (CaL), that combines normalized droplet volume with geometrical parameters (length of dispersed and continuous phase channels) and flow parameters (interfacial tension, phase viscosity and velocity) in a power law relationship. CaL effectively captures the transition from squeezing to dripping regimes of droplet generation, providing essential insights into the design requirements for suction-driven droplet generation. These findings are key to standardize microfluidic flow-focusing devices that can achieve the desired droplet generation behavior with optimal pressure consumption.

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修改毛细管数量,使抽吸驱动微流控技术中的液滴生成标准化
摘要 在基于吸力控制流量的液滴微流控装置中,微通道的几何形状和出口处的吸力压力控制着影响液滴生成的两相的动态特性。因此,了解几何形状和抽吸压力在液滴生成动态过程中的作用对于开发预测模型至关重要。我们对不同控制参数下流动聚焦装置中液滴生成的特性进行了全面分析。我们利用这些结果提出了一个比例论证,并提出了一个称为修正毛细管数(CaL)的控制参数,该参数将归一化液滴体积与几何参数(分散相和连续相通道的长度)和流动参数(界面张力、相粘度和速度)结合起来,形成幂律关系。CaL 有效捕捉了液滴生成从挤压到滴落的过渡过程,为吸力驱动液滴生成的设计要求提供了重要见解。这些发现是实现微流体流动聚焦设备标准化的关键,这些设备能以最佳的压力消耗实现理想的液滴生成行为。
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来源期刊
Microfluidics and Nanofluidics
Microfluidics and Nanofluidics 工程技术-纳米科技
CiteScore
4.80
自引率
3.60%
发文量
97
审稿时长
2 months
期刊介绍: Microfluidics and Nanofluidics is an international peer-reviewed journal that aims to publish papers in all aspects of microfluidics, nanofluidics and lab-on-a-chip science and technology. The objectives of the journal are to (1) provide an overview of the current state of the research and development in microfluidics, nanofluidics and lab-on-a-chip devices, (2) improve the fundamental understanding of microfluidic and nanofluidic phenomena, and (3) discuss applications of microfluidics, nanofluidics and lab-on-a-chip devices. Topics covered in this journal include: 1.000 Fundamental principles of micro- and nanoscale phenomena like, flow, mass transport and reactions 3.000 Theoretical models and numerical simulation with experimental and/or analytical proof 4.000 Novel measurement & characterization technologies 5.000 Devices (actuators and sensors) 6.000 New unit-operations for dedicated microfluidic platforms 7.000 Lab-on-a-Chip applications 8.000 Microfabrication technologies and materials Please note, Microfluidics and Nanofluidics does not publish manuscripts studying pure microscale heat transfer since there are many journals that cover this field of research (Journal of Heat Transfer, Journal of Heat and Mass Transfer, Journal of Heat and Fluid Flow, etc.).
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