Relationship between antibody titer than the Incidence of Infection After Complete Dose of COVID-19 Astrazeneca Vaccination Based on Sociodemographics

Stefan Lukas, Diana Laila Ramatillah, Y. Aldi, F. Wahyuni
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Abstract

Background: Vaccine is an essential tool to limit the health of the COVID -19 pandemic and one of the vaccines that got permitted to used is AstraZeneca Vaccine. The base of the AstraZeneca is the viral vector vaccine. This vaccine has a more advanced method that uses a modified virus to trigger antibodies to make herd immunity for people. Objective: To found correlation between antibody titer than the incidence of Covid infection after complete dose vaccination base on sociodemographics Method: Observasional prospective Cohort method was use in this study with a convenience sampling design. Inclusion criteria were all Indonesian citizens above 18 years old (n=113) who were vaccinated at UTA 45 Jakarta Vaccine Center with no history of COVID -19 before the vaccination and had filled up the informed consents. Results: there were 43 (38%) respondents infected Covid-19 after vaccinated full dosesConclusion: Base on this study, it was found that there was a correlation between sociodemographics after vaccinated full doses AstraZeneca, gender, age, comorbid, smoking, and drinking than infected Covid -19 (P-value < 0.05)). Keywords: Astrazeneca vaccine, Antibody titer, COVID-19.
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基于社会人口统计学的 COVID-19 阿斯利康疫苗全程接种后抗体滴度与感染发生率之间的关系
背景:疫苗是限制 COVID -19 大流行的重要工具,而获准使用的疫苗之一是阿斯利康疫苗。阿斯利康疫苗的基础是病毒载体疫苗。这种疫苗采用了一种更先进的方法,即利用改良病毒触发抗体,使人们产生群体免疫力。目的在社会人口统计学的基础上,发现抗体滴度与全剂量接种后 Covid 感染率之间的相关性:本研究采用前瞻性队列观察法和便利抽样设计。纳入标准为所有在雅加达UTA 45疫苗中心接种疫苗的18岁以上印尼公民(n=113),接种前无COVID -19病史,并已填写知情同意书。结果:43 名受访者(38%)在接种全部剂量的疫苗后感染了 COVID-19:根据这项研究发现,接种阿斯利康全剂量疫苗后,社会人口统计学、性别、年龄、合并症、吸烟和饮酒与感染Covid-19之间存在相关性(P值<0.05))。关键词: 阿斯利康疫苗阿斯利康疫苗 抗体滴度 COVID-19
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