The Use of Toxicokinetic Information for Setting Concentrations of In Vitro Toxicity Tests and for Interpreting Their Results: A Proposed Workflow

Q2 Health Professions Applied In Vitro Toxicology Pub Date : 2024-03-01 DOI:10.1089/aivt.2023.0018
R. Landsiedel, B. Birk, Philipp Demuth, E. Fabian, Nicola J. Hewitt, H. Hollnagel, Julia Scheel
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来源期刊
Applied In Vitro Toxicology
Applied In Vitro Toxicology Health Professions-Medical Laboratory Technology
CiteScore
2.70
自引率
0.00%
发文量
13
期刊介绍: Applied In Vitro Toxicology is a peer-reviewed journal providing the latest research on the application of alternative in vitro testing methods for predicting adverse effects in the pharmaceutical, chemical, and personal care industries. This Journal aims to address important issues facing the various chemical industries, including regulatory requirements; the reduction, refinement, and replacement of animal testing; new screening methods; evaluation of new cell and tissue models; and the most appropriate methods for assessing safety and satisfying regulatory demands. The Journal also delivers the latest views and opinions of developers of new models, end users of the models, academic laboratories that are inventing new tools, and regulatory agencies in the United States, Europe, Latin America, Australia and Asia. Applied In Vitro Toxicology is the journal that scientists involved with hazard identification and risk assessment will read to understand how new and existing in vitro methods are applied, and the questions for which these models provide answers. Applied In Vitro Toxicology coverage includes: -Applied in vitro toxicology industry standards -New technologies developed for applied in vitro toxicology -Data acquisition, cleaning, distribution, and best practices -Data protection, privacy, and policy -Business interests from research to product -The changing role of in vitro toxicology -Visualization and design principles of applied in vitro toxicology infrastructures -Physical interfaces and robotics -Opportunities around applied in vitro toxicology
期刊最新文献
In Vitro Assessment of Translocation and Toxicological Effects of Nicotine and Ethyl Maltol from e-Cigarettes Using Air–Liquid Interface-Cultured Bronchial Epithelial Cells The Use of Toxicokinetic Information for Setting Concentrations of In Vitro Toxicity Tests and for Interpreting Their Results: A Proposed Workflow Correction to: Assessing Experimental Uncertainty in Defined Approaches: Borderline Ranges for In Chemico and In Vitro Skin Sensitization Methods Determined from Ring Trial Data, by Kolle, et al. Appl In Vitro Toxicol 2021;7(3):102–111; doi: 10.1089/aivt.2021.0003 Protective Effect of Resveratrol on Cytotoxicity, Genotoxicity, and Oxidative Stress Caused by Cyclophosphamide and Methotrexate in Bone Marrow Stem Cell Line and Blood Lymphocytes of the Rat Validation of the VITROCELL Mammalian 48 Exposure Module Using In Vitro Cytotoxicity via the Neutral Red Uptake Assay in Chinese Hamster Ovary Cells Following Exposure to Whole Smoke from Combustible Cigarettes
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