Endodermal sinus tumor of ovary with metastasis from breast carcinoma: a case report

Chandni, Nirbhay Kumar Bind, Neeta Meena
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Abstract

Endodermal sinus tumor is malignant germ cell tumor of ovary. Endodermal sinus tumours (EST) also know as yolk sac tumor are rare about 1% of ovarian malignancies and highly malignant tumours occurring primarily in children and young women. Overall survival is poor. In present case patient was breast cancer survivor and completed her treatment for breast cancer 10 years back. Later on she developed rapidly growing bilateral ovarian mass. Tumor markers of epithelial ovarian tumor were raised. Gross examination was suggestive of Krukenberg tumor and on histopathological examination that was suggestive of endodermal sinus tumor, Finally, Immunohistochemistry helped to conclude the diagnosis of metastatic ovarian tumor from breast carcinoma.
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卵巢内皮窦肿瘤伴乳腺癌转移:病例报告
内胚窦肿瘤是卵巢的恶性生殖细胞肿瘤。内胚层窦肿瘤(EST)又称卵黄囊肿瘤,是一种罕见的卵巢恶性肿瘤,约占卵巢恶性肿瘤的 1%,主要发生在儿童和年轻女性身上,是高度恶性肿瘤。总生存率很低。本病例中的患者是乳腺癌幸存者,10 年前完成了乳腺癌治疗。后来,她的双侧卵巢肿块迅速增大。上皮性卵巢肿瘤的肿瘤标志物升高。大体检查提示为 Krukenberg 肿瘤,组织病理学检查提示为内胚层窦肿瘤,最后,免疫组化检查帮助确诊为乳腺癌转移性卵巢肿瘤。
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