Tracking immunization milestones: a community-based survey of child vaccination compliance from birth to one year age in India

Ayub Khan, Hari Shankar
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Abstract

Background: Immunization is a crucial public health intervention that significantly reduces childhood morbidity and mortality. In India, despite the efforts of programs like the universal immunization program (UIP), there remain significant challenges in ensuring timely vaccination. This study investigates the compliance with immunization schedules among children in a rural area of Varanasi, India, from birth to one year of age. Methods: A prospective cohort study was conducted from November 2022 to February 2024, involving 150 newborns. The participants included infants delivered via both caesarean section (CS) and vaginal delivery. Monthly delivery lists from the community health centre facilitated the identification and random selection of eligible newborns. The study entailed a baseline visit followed by four quarterly follow-ups over one year. Results: The study revealed significant delays in vaccination timing. Hepatitis B had the highest on-time rate at 99.3%, while rotavirus-1 had the highest delay at 35.5%. Other notable delays included BCG (15.8%) and oral polio vaccine (OPV) birth (25.3%). The on-time rates for subsequent doses of OPV and pentavalent vaccines ranged from 65.9% to 77.7%, with delays observed in about a quarter of the vaccinations. Socio-demographic factors indicated a predominance of joint families (85.3%), with most parents having completed high school or higher education. Conclusions: The findings highlight the need for enhanced strategies to improve adherence to vaccination schedules in rural areas. Significant delays in immunization, particularly for rota-1 and OPV doses, underscore the necessity for targeted interventions.
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跟踪免疫接种里程碑:印度对出生至一岁儿童疫苗接种遵守情况的社区调查
背景:免疫接种是一项重要的公共卫生干预措施,可显著降低儿童发病率和死亡率。在印度,尽管全民免疫计划(UIP)等项目做出了努力,但在确保及时接种疫苗方面仍存在重大挑战。本研究调查了印度瓦拉纳西农村地区儿童从出生到一岁期间遵守免疫计划的情况:方法:2022 年 11 月至 2024 年 2 月期间,对 150 名新生儿进行了前瞻性队列研究。参与者包括剖腹产(CS)和阴道分娩的婴儿。社区医疗中心每月提供的分娩名单有助于识别和随机选择符合条件的新生儿。研究包括一次基线访问和一年内的四次季度随访:研究显示,接种疫苗的时间严重滞后。乙型肝炎的按时接种率最高,为 99.3%,而轮状病毒-1 的延迟接种率最高,为 35.5%。其他值得注意的延误还包括卡介苗(15.8%)和口服脊髓灰质炎疫苗(25.3%)。随后接种的口服脊髓灰质炎疫苗和五价疫苗的按时接种率从 65.9% 到 77.7% 不等,其中约四分之一的疫苗接种出现了延误。社会人口因素表明,大多数家庭为合家团聚(85.3%),大多数父母已完成高中或高等教育:结论:研究结果表明,有必要加强战略,提高农村地区对疫苗接种计划的依从性。免疫接种,尤其是轮状 1 型疫苗和 OPV 疫苗接种的严重延误突出表明,有必要采取有针对性的干预措施。
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