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Hypertensive disorders in pregnancy as primary and associated indications for caesarean section 妊娠期高血压疾病作为剖腹产的主要和相关指征
Pub Date : 2024-08-09 DOI: 10.18203/2320-1770.ijrcog20242274
Sabina Parveen, Jasmine
Background: Hypertensive disorders in pregnancy (HDP) are a group of conditions characterized by high blood pressure during pregnancy. This can include gestational hypertension, preeclampsia, eclampsia, and chronic hypertension with superimposed preeclampsia. The HDP elicits various adverse outcomes like preterm delivery, placental abruptions and increased rate of caesarean delivery. Hence, the present study was carried out to evaluate the frequency and associated indication of caesarean section (CS) in HDP.Methods: A retrospective study was carried out on 110 pregnant women with HDP for a period of one year. The patient’s details like mode of delivery and the indication of CS delivery were recorded.Results: The most common HDP was gestational hypertension in 76 (69.1%) and the mean age of the patients was 24.24±4.42 years. Out of 110 HDP cases, 97 had delivered through CS with a rate of 88.2%. The main indication for caesarean delivery was previous LSCS in 22 (22.68%) of the patients, followed by gestational hypertension in 18 (18.56%), severe preeclampsia in 11 (11.34%) and preeclampsia in 8 (8.25%).Conclusions: HDP are a significant factor in the negative outcomes experienced by both mothers and their babies. Routine pregnancy check-ups, early detection, immediate multifaceted treatment, and optimal time for delivery are crucial in reducing the frequency of complications and maternal mortality. Timely referral and management of these cases at specialized neonatal centers can significantly decrease perinatal mortality rates. 
背景:妊娠期高血压疾病(HDP)是一组以妊娠期高血压为特征的疾病。其中包括妊娠高血压、子痫前期、子痫和慢性高血压合并子痫前期。HDP 会导致各种不良后果,如早产、胎盘早剥和剖腹产率增加。因此,本研究旨在评估 HDP 患者剖宫产的频率和相关指征:对 110 名 HDP 孕妇进行了为期一年的回顾性研究。方法:对 110 名 HDP 孕妇进行了为期一年的回顾性研究,记录了患者的详细情况,如分娩方式和 CS 分娩指征:最常见的 HDP 是妊娠高血压(76 例,占 69.1%),患者平均年龄为(24.24±4.42)岁。在 110 例 HDP 中,97 例通过 CS 分娩,比例为 88.2%。22例(22.68%)患者的主要剖宫产指征是既往LSCS,其次是妊娠高血压18例(18.56%)、重度子痫前期11例(11.34%)和子痫前期8例(8.25%):HDP是造成母婴不良结局的一个重要因素。常规孕期检查、早期发现、立即进行多方面治疗以及最佳分娩时间对于降低并发症发生率和孕产妇死亡率至关重要。在新生儿专科中心及时转诊和处理这些病例,可以大大降低围产期死亡率。
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引用次数: 0
Tracking immunization milestones: a community-based survey of child vaccination compliance from birth to one year age in India 跟踪免疫接种里程碑:印度对出生至一岁儿童疫苗接种遵守情况的社区调查
Pub Date : 2024-08-08 DOI: 10.18203/2320-1770.ijrcog20242267
Ayub Khan, Hari Shankar
Background: Immunization is a crucial public health intervention that significantly reduces childhood morbidity and mortality. In India, despite the efforts of programs like the universal immunization program (UIP), there remain significant challenges in ensuring timely vaccination. This study investigates the compliance with immunization schedules among children in a rural area of Varanasi, India, from birth to one year of age.Methods: A prospective cohort study was conducted from November 2022 to February 2024, involving 150 newborns. The participants included infants delivered via both caesarean section (CS) and vaginal delivery. Monthly delivery lists from the community health centre facilitated the identification and random selection of eligible newborns. The study entailed a baseline visit followed by four quarterly follow-ups over one year.Results: The study revealed significant delays in vaccination timing. Hepatitis B had the highest on-time rate at 99.3%, while rotavirus-1 had the highest delay at 35.5%. Other notable delays included BCG (15.8%) and oral polio vaccine (OPV) birth (25.3%). The on-time rates for subsequent doses of OPV and pentavalent vaccines ranged from 65.9% to 77.7%, with delays observed in about a quarter of the vaccinations. Socio-demographic factors indicated a predominance of joint families (85.3%), with most parents having completed high school or higher education.Conclusions: The findings highlight the need for enhanced strategies to improve adherence to vaccination schedules in rural areas. Significant delays in immunization, particularly for rota-1 and OPV doses, underscore the necessity for targeted interventions.
背景:免疫接种是一项重要的公共卫生干预措施,可显著降低儿童发病率和死亡率。在印度,尽管全民免疫计划(UIP)等项目做出了努力,但在确保及时接种疫苗方面仍存在重大挑战。本研究调查了印度瓦拉纳西农村地区儿童从出生到一岁期间遵守免疫计划的情况:方法:2022 年 11 月至 2024 年 2 月期间,对 150 名新生儿进行了前瞻性队列研究。参与者包括剖腹产(CS)和阴道分娩的婴儿。社区医疗中心每月提供的分娩名单有助于识别和随机选择符合条件的新生儿。研究包括一次基线访问和一年内的四次季度随访:研究显示,接种疫苗的时间严重滞后。乙型肝炎的按时接种率最高,为 99.3%,而轮状病毒-1 的延迟接种率最高,为 35.5%。其他值得注意的延误还包括卡介苗(15.8%)和口服脊髓灰质炎疫苗(25.3%)。随后接种的口服脊髓灰质炎疫苗和五价疫苗的按时接种率从 65.9% 到 77.7% 不等,其中约四分之一的疫苗接种出现了延误。社会人口因素表明,大多数家庭为合家团聚(85.3%),大多数父母已完成高中或高等教育:结论:研究结果表明,有必要加强战略,提高农村地区对疫苗接种计划的依从性。免疫接种,尤其是轮状 1 型疫苗和 OPV 疫苗接种的严重延误突出表明,有必要采取有针对性的干预措施。
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引用次数: 0
Menstrual hygiene among the undergraduate medical college students in Churachandpur Medical College, Manipur, North Eastern state of India 印度东北部曼尼普尔邦 Churachandpur 医学院本科生的月经卫生状况
Pub Date : 2024-08-08 DOI: 10.18203/2320-1770.ijrcog20242266
Okram Sarda Devi, Melody Vashum, Guddi Laishram
Background: Menstruation is very important monthly event in the life of adolescent. Educating girls and women about menstrual hygiene is vital to break taboos, promote health, and empower them to manage their periods hygienically and confidently. For this knowing the awareness and practices and prevalence menstruation related health issue are also important.Methods: The study is a cross-sectional observational study done on all undergraduate’s female medical graduates of Churachandpur medical college (Imphal Campus) Manipur. from May 15th, 2024 to June 15th, 2024.Results: In the current study, it is noted that 100% of participants have menstrual related health issues and dysmenorrhea was the commonest among the menstrual related health issues. And a huge number of students did not receive treatment for the menstrual related health issues. Less than 50% of students have accessibility to separate toilet. And 55% have restriction during menstrual cycle.Conclusions: It is noted from the current study that there are numerous problems regarding menstrual hygiene that need to be address. So, providing more accessible menstrual clinics is crucial. 
背景介绍月经是青少年生活中非常重要的月事。对女孩和妇女进行经期卫生教育,对于打破禁忌、促进健康、使她们有能力以卫生和自信的方式管理自己的经期至关重要。为此,了解与月经有关的健康问题的意识、做法和流行程度也很重要:本研究是一项横断面观察性研究,研究对象是曼尼普尔 Churachandpur 医学院(英帕尔校区)的所有医学本科女毕业生,研究时间为 2024 年 5 月 15 日至 2024 年 6 月 15 日:在本次研究中,100% 的参与者都有月经相关的健康问题,其中痛经是最常见的月经相关健康问题。大量学生没有接受月经相关健康问题的治疗。只有不到 50%的学生可以使用独立厕所。55%的学生在月经周期受到限制:从本次研究中可以看出,月经卫生方面有许多问题需要解决。因此,提供更方便的月经诊所至关重要。
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引用次数: 0
A study on feto-maternal outcome in patients with preterm premature rupture of membranes 早产胎膜早破患者的母胎结局研究
Pub Date : 2024-07-22 DOI: 10.18203/2320-1770.ijrcog20241983
Niki Shah, Vipul S. Patel, Anisa Shaikh
Background: Preterm premature rupture of membranes (PPROM) is rupture of fetal membranes prior to labor in pregnancies between 28-37 weeks. PPROM is associated with significant maternal and neonatal morbidity or mortality. The present study was conducted to evaluate risk factor and etiology of PPROM and its fetomaternal effect in tertiary care hospital.Methods: A cross-sectional study was conducted in the department of obstetrics and gynaecology, SMS Hospital, Ahemdabad. From August 2023 to February 2024.The study included 50 pregnant women between 28-37 weeks gestation with PPROM were subjected to detailed history and examination. Each patient was followed till her delivery and fetomaternal outcome was recorded.Results: PPROM is a fair complication of pregnancy. 80% were belongs to 20-29 age, 70% were unbooked, 76% from low SE-class, 68% with gestational age of 34-36 weeks. Vaginal delivery was common 58%. The babies born to mothers with PPROM more in weight of 2-2.5 kg (48%). 34 had no risk factors to develop PPROM. Most common etiology for PPROM infection 16% and malpresentation 10%. Most of the mothers with PPROM had no complications. 17 (34%) babies required NICU admissions for complaints of premturity, respiratory distress, birth asphyxia, and sepsis. RDS was most common neonatal complication. 2 neonatal deaths in this study due to RDS and prematurity.Conclusions: Effective PPROM Mx involves evaluating the risks and advantage of conservative Mx strategies. Whenever possible, Rx should be focused towards prophylactic use of antibiotics and steroids during pregnancy can reduce fetal and mother morbidity and mortality. Termination of pregnancy should be considered at the 1st sign of chorioamnionitis. 
背景:早产胎膜早破(PPROM)是指怀孕 28-37 周的孕妇在分娩前胎膜破裂。早产胎膜早破与孕产妇和新生儿的严重发病率或死亡率相关。本研究旨在评估 PPROM 的风险因素、病因及其对三级医院孕产妇的影响:方法:在阿赫姆达巴德 SMS 医院妇产科进行了一项横断面研究。研究对象包括 50 名妊娠 28-37 周、患有先兆流产(PPROM)的孕妇,她们都接受了详细的病史询问和检查。对每位患者进行了随访直至分娩,并记录了胎儿和产妇的结局:结果:PPROM 是一种常见的妊娠并发症。80%的孕妇年龄在 20-29 岁之间,70%的孕妇没有预约,76%的孕妇来自低 SE 级,68%的孕妇孕龄在 34-36 周之间。阴道分娩占 58%。患有先兆流产的母亲所生的婴儿体重多在 2-2.5 公斤之间(48%)。34名产妇没有罹患早产儿先兆流产的风险因素。导致早产儿猝死的最常见病因是感染,占 16%,胎位不正占 10%。大多数患有先兆流产的母亲没有并发症。17(34%)名婴儿因早产、呼吸窘迫、出生窒息和败血症而需要入住新生儿重症监护室。RDS 是最常见的新生儿并发症。本研究中有 2 名新生儿死于 RDS 和早产:有效的早产儿窒息治疗包括评估保守治疗策略的风险和优势。在可能的情况下,药物治疗应侧重于在孕期预防性使用抗生素和类固醇,以降低胎儿和母亲的发病率和死亡率。一旦出现绒毛膜羊膜炎的迹象,应考虑终止妊娠。
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引用次数: 0
Modes and timing of delivery along with maternal and neonatal conditions for preeclamptic patients of Rajshahi, Bangladesh 孟加拉国拉杰沙希先兆子痫患者的分娩方式和时间以及产妇和新生儿状况
Pub Date : 2024-07-19 DOI: 10.18203/2320-1770.ijrcog20241978
Sultana Nasima Akhter, M. R. Islam, Parvez Hassan
Background: We studied the gynaecological, obstetrical and family history, complications arisen, timing and mode of delivery, and post-delivery maternal and neonatal health conditions for preeclamptic patients in Rajshahi, Bangladesh. Methods:  Using a cross-sectional longitudinal design, 90 women hospitalized with preeclampsia in 7 hospitals of Rajshahi, Bangladesh were considered, of which two-thirds were from tertiary referral Rajshahi medical college hospital. The data were collected by interviewing the patients, physical examinations and analyzing patients’ pathological profile. For statistical analyses, SPSS software was employed.    Results:  The 58% of the preeclamptic patients became pregnant earlier, of which 56% had NVD, 24 % C/S and 20% abortion. The 85% patients had history of chronic constipation, ashma, blood transfusion, UTI, hypertension, liver disease, diabetes and preeclampsia. Regarding past surgical history, 40% had Appendisectomy, DE and C, MR, left Salphingo-oophorectomy and CS. Their gestational age ranged 40-32 weeks, averaging 37 weeks. About three-fourths of the patients’ deliveries were made by CS. Generally, patients’ BP fell down after delivery. One patient out of 88 had died after giving birth, but her female infant (weighing 2.0 kg) was in good condition. Only one case of twin-pregnancy was recorded. After giving births, 28% of mother had no complications, whereas 56% had mild complications and 16% had severe complications. Male children dominated (60%) over female children (40%). A total of 9 (10%) neonatal deaths were recorded. Among alive infants, 42% were premature. About 28% of the newborn infants had no complications, while 16% had mild complications and 56% had severe complications including asphyxia, IUGR, etc.      Conclusions: After delivery (CS was 75%), mothers’ health was good, but the infants’ health deteriorated. Consequently, 1% maternal death and 10% neonatal deaths were recorded.                
背景:我们研究了孟加拉国拉杰沙希的先兆子痫患者的妇科、产科和家族病史、出现的并发症、分娩时间和方式以及产后产妇和新生儿的健康状况。研究方法 采用横断面纵向设计,考虑了孟加拉国拉杰沙希市 7 家医院的 90 名子痫前期住院妇女,其中三分之二来自三级转诊的拉杰沙希医学院附属医院。数据收集方式包括对患者进行访谈、体格检查和病理分析。统计分析采用 SPSS 软件。 结果 58%的先兆子痫患者早孕,其中 56% 患有先兆子痫,24% 患有先兆流产,20% 患有流产。85%的患者有慢性便秘、灰黄病、输血、尿毒症、高血压、肝病、糖尿病和子痫前期病史。关于既往手术史,40%的患者曾做过阑尾切除术、DE 和 C、MR、左侧输卵管切除术和 CS。她们的孕周在 40-32 周之间,平均为 37 周。约四分之三的患者是通过 CS 分娩的。一般来说,患者在分娩后血压会下降。88 例患者中有 1 例在分娩后死亡,但其女婴(重 2.0 千克)状况良好。只有一例双胎妊娠。分娩后,28%的产妇没有并发症,56%有轻微并发症,16%有严重并发症。男婴占 60%,女婴占 40%。共记录了 9 例(10%)新生儿死亡病例。在存活的婴儿中,42%为早产儿。约 28% 的新生儿没有并发症,16% 有轻微并发症,56% 有严重并发症,包括窒息、IUGR 等。 结论分娩后(CS 为 75%),母亲的健康状况良好,但婴儿的健康状况恶化。因此,产妇死亡人数为 1%,新生儿死亡人数为 10%。
{"title":"Modes and timing of delivery along with maternal and neonatal conditions for preeclamptic patients of Rajshahi, Bangladesh","authors":"Sultana Nasima Akhter, M. R. Islam, Parvez Hassan","doi":"10.18203/2320-1770.ijrcog20241978","DOIUrl":"https://doi.org/10.18203/2320-1770.ijrcog20241978","url":null,"abstract":"Background: We studied the gynaecological, obstetrical and family history, complications arisen, timing and mode of delivery, and post-delivery maternal and neonatal health conditions for preeclamptic patients in Rajshahi, Bangladesh. \u0000Methods:  Using a cross-sectional longitudinal design, 90 women hospitalized with preeclampsia in 7 hospitals of Rajshahi, Bangladesh were considered, of which two-thirds were from tertiary referral Rajshahi medical college hospital. The data were collected by interviewing the patients, physical examinations and analyzing patients’ pathological profile. For statistical analyses, SPSS software was employed.    \u0000Results:  The 58% of the preeclamptic patients became pregnant earlier, of which 56% had NVD, 24 % C/S and 20% abortion. The 85% patients had history of chronic constipation, ashma, blood transfusion, UTI, hypertension, liver disease, diabetes and preeclampsia. Regarding past surgical history, 40% had Appendisectomy, DE and C, MR, left Salphingo-oophorectomy and CS. Their gestational age ranged 40-32 weeks, averaging 37 weeks. About three-fourths of the patients’ deliveries were made by CS. Generally, patients’ BP fell down after delivery. One patient out of 88 had died after giving birth, but her female infant (weighing 2.0 kg) was in good condition. Only one case of twin-pregnancy was recorded. After giving births, 28% of mother had no complications, whereas 56% had mild complications and 16% had severe complications. Male children dominated (60%) over female children (40%). A total of 9 (10%) neonatal deaths were recorded. Among alive infants, 42% were premature. About 28% of the newborn infants had no complications, while 16% had mild complications and 56% had severe complications including asphyxia, IUGR, etc.      \u0000Conclusions: After delivery (CS was 75%), mothers’ health was good, but the infants’ health deteriorated. Consequently, 1% maternal death and 10% neonatal deaths were recorded.                ","PeriodicalId":14225,"journal":{"name":"International journal of reproduction, contraception, obstetrics and gynecology","volume":"116 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141822237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ovarian fibroma thecoma with serous cystadenoma-an unusual combination in young patient: a case report 卵巢纤维瘤肉瘤伴浆液性囊腺瘤--年轻患者的罕见组合:病例报告
Pub Date : 2024-07-18 DOI: 10.18203/2320-1770.ijrcog20241970
Tejas Gopalkrishnan
The article is a case report of a 16-year-old patient who came to tertiary care centre in western part of India with a case of ovarian tumor with torsion. The ovarian mass was a composite tumor of ovarian thecoma fibroma and serous cystadenoma. The detection of ovarian mass was made with ultrasonography and CT scan. Her tumor markers were not raised. The patient was managed surgically with ovarian mass removal along with removal of non-salvageable ovary. The present literature has very few cases of ovarian thecoma fibroma with serous cystadenoma and there is no such case occurring at a young age of 16 years. Such a case needs to be kept in mind when dealing with ovarian masses in young age as a solid mass with a cystic tumor may raise a suspicion of malignancy in preliminary evaluation. Also, further evaluation is necessary as to occurrence of such composite tumors and that too in younger age groups. 
本文是一份病例报告,印度西部的一家三级医疗中心收治了一名卵巢肿瘤伴扭转的 16 岁患者。卵巢肿块是卵巢肉瘤纤维瘤和浆液性囊腺瘤的复合肿瘤。卵巢肿块是通过超声波检查和 CT 扫描发现的。她的肿瘤标志物没有升高。患者接受了卵巢肿块切除手术,同时切除了无法挽救的卵巢。目前的文献中很少有卵巢肉瘤纤维瘤合并浆液性囊腺瘤的病例,也没有一例发生在 16 岁的年轻女性身上。在处理幼年卵巢肿块时需要注意这种病例,因为在初步评估时,实性肿块伴囊性肿瘤可能会引起恶性肿瘤的怀疑。此外,有必要进一步评估此类复合肿瘤的发生率,而且是在年轻群体中。
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引用次数: 0
Prevalence of preeclampsia and its associated risk factors in Rajshahi region, Bangladesh 孟加拉国拉杰沙希地区先兆子痫的发病率及其相关风险因素
Pub Date : 2024-07-15 DOI: 10.18203/2320-1770.ijrcog20241965
Sultana Nasima Akhter, Rokeya Khatun, M. Shamima, Nahid Sultana, Amina Khatun, Rawshan Akhtar, Nargis Jahan, Monowara Begum, M. J. Haque, Parvez Hassan
Background: Although preeclampsia claims lives of 70,000 mothers and 500,000 newborns each year, in Bangladesh the comprehensive data-sets are not well-documented. We studied the prevalence of preeclampsia, its trend and the associated risk factors in Rajshahi, Bangladesh.Methods: Using a cross-sectional longitudinal design, 90 women hospitalized with preeclampsia in 7 hospitals of Rajshahi, Bangladesh were considered in the study, of which Rajshahi medical college hospital (RMCH) is a tertiary referral hospital. The data were collected by interviewing the patients, physical examinations and analyzing patients’ pathological profile. For statistical analyses, SPSS software was employed.    Results: During the five years (2013-2017), RMCH admitted pregnant mothers for delivery or with obstructed complications had increased from 11,523 to 17,201, leading to an increase in preeclamptic patients from 407 to 435. Its prevalence rate (3.21%) was found to be decreased linearly with time. The preeclamptic patients were of 16-40 years, averaging 25.90±0.65 years. The youngest (£20 years) preeclamptic mothers (24%) were at high risk of preeclampsia. The obese (40%) and overweight (29%) preeclamptic mothers experienced severe oedema, headache, vomiting, lower abdominal pain and hyperacidity. About three-fourths of the concerned patients were of lower socio-economic class, of which the majority was below education level 10. The majority were from joint families (58%) who took less than 2.2 L of drinking water per day.Conclusions: The average prevalence preeclampsia rate was 3.21% that was found to decrease linearly with time. The youngest but obese (BMI of ³30 kg/m2) mothers were vulnerable for preeclampsia. Other risk factors include lower socio-economic class, less education, white complexion, joint family type and taking less amount of fluid.         
背景:尽管子痫前期每年夺去 7 万名母亲和 50 万名新生儿的生命,但在孟加拉国,全面的数据集并没有得到很好的记录。我们研究了孟加拉国拉杰沙希的子痫前期发病率、发病趋势及相关风险因素:采用横断面纵向设计,研究对象为孟加拉国拉杰沙希市 7 家医院的 90 名子痫前期住院妇女,其中拉杰沙希医学院附属医院(RMCH)是一家三级转诊医院。数据是通过询问患者、体格检查和分析患者病理特征收集的。统计分析采用 SPSS 软件。 结果五年间(2013-2017年),RMCH收治的待产或有难产并发症的孕产妇从11523人增加到17201人,导致先兆子痫患者从407人增加到435人。随着时间的推移,其发病率(3.21%)呈线性下降趋势。子痫前期患者的年龄在 16-40 岁之间,平均年龄(25.90±0.65)岁。最年轻(20 岁以下)的子痫前期母亲(24%)是子痫前期的高危人群。肥胖(40%)和超重(29%)的子痫前期母亲会出现严重水肿、头痛、呕吐、下腹痛和胃酸过多。约四分之三的相关患者属于社会经济地位较低的阶层,其中大多数人的教育程度低于 10 级。大多数患者来自联合家庭(58%),每天的饮水量少于 2.2 升:子痫前期的平均发病率为 3.21%,随着时间的推移呈线性下降。最年轻但肥胖(体重指数为 30 kg/m2)的母亲易患子痫前期。其他风险因素包括社会经济阶层较低、受教育程度较低、肤色较白、联合家庭类型以及液体摄入量较少。
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引用次数: 0
A comparative study of letrozole and clomiphene citrate for ovulation induction in women with polycystic ovarian syndrome: a randomized controlled trial 来曲唑和枸橼酸氯米芬诱导多囊卵巢综合征妇女排卵的比较研究:随机对照试验
Pub Date : 2024-07-09 DOI: 10.18203/2320-1770.ijrcog20241954
Subashree Ilangovan
Background: Effective ovulation induction is crucial in management of polycystic ovarian syndrome (PCOS) related infertility. Clomiphene citrate (CC) has long been the first line of treatment for inducing ovulation in women with PCOS. Letrozole, an aromatase inhibitor, has emerged as a promising alternative to CC for ovulation induction. The present study was aimed to compare efficacy and safety of letrozole versus CC for ovulation induction in women with PCOS.Methods: This study consists of 384 PCOS women, randomized into two groups: Letrozole (2.5 mg/day) and CC (50 mg/day), both administered from day 3 to day 7 of the menstrual cycle. The primary outcome was the ovulation rate, confirmed by serum progesterone levels >10 ng/ml. Secondary outcomes included clinical pregnancy rate, live birth rate, endometrial thickness, adverse effects, cost-effectiveness, and patient satisfaction. Participants were monitored through transvaginal ultrasound and serum progesterone measurements.Results: Ovulation was achieved in 76.0% of participants in the letrozole group compared to 55.2% in the CC group (p<0.001). Clinical pregnancy rates were significantly higher in the letrozole group (44.8%) compared to the CC group (28.1%) (p<0.001). Similarly, live birth rates were higher with letrozole (36.5% vs. 22.4%; p=0.002). Endometrial thickness was greater in the letrozole group (8.7 mm vs. 7.5 mm; p<0.001). Adverse effects, were significantly lower in the letrozole group.Conclusions: Letrozole is more effective than CC in inducing ovulation and achieving higher pregnancy and live birth rates in women with PCOS.
背景:有效的促排卵是治疗多囊卵巢综合征(PCOS)相关不孕症的关键。长期以来,枸橼酸氯米芬(CC)一直是多囊卵巢综合征妇女诱导排卵的一线治疗药物。来曲唑是一种芳香化酶抑制剂,已成为CC诱导排卵的一种有前途的替代疗法。本研究旨在比较来曲唑与CC对多囊卵巢综合征妇女诱导排卵的疗效和安全性:本研究由 384 名多囊卵巢综合征妇女组成,随机分为两组:来曲唑(2.5毫克/天)和CC(50毫克/天),均在月经周期的第3天至第7天用药。主要结果是排卵率,通过血清孕酮水平大于 10 纳克/毫升来确认。次要结果包括临床妊娠率、活产率、子宫内膜厚度、不良反应、成本效益和患者满意度。通过经阴道超声和血清孕酮测量对参与者进行监测:来曲唑组76.0%的参与者实现了排卵,而CC组为55.2%(P<0.001)。来曲唑组的临床妊娠率(44.8%)明显高于CC组(28.1%)(p<0.001)。同样,来曲唑组的活产率更高(36.5% 对 22.4%;P=0.002)。来曲唑组的子宫内膜厚度更大(8.7 毫米对 7.5 毫米;P<0.001)。来曲唑组的不良反应明显降低:结论:来曲唑比CC更能有效诱导多囊卵巢综合征妇女排卵,并提高妊娠率和活产率。
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引用次数: 0
Audit of caesarean deliveries in a tertiary care rural hospital of Bangalore, Karnataka, India 印度卡纳塔克邦班加罗尔一家三级护理农村医院剖腹产情况审计
Pub Date : 2024-07-06 DOI: 10.18203/2320-1770.ijrcog20241951
Ananya Sarvotham, A. A. Fathima, Chaitanya Indrani
Background: Due to the rise in caesarean section rates Robsons classification system was adopted by WHO as a global standard to asses and audit the caesarean section rates within different hospitals, to reduce the caesarean section rates and the associated complications and also improve patient care along with it. The aim of the present study is to audit the number of caesarean deliveries in the hospital. Objective were to audit the caesarean deliveries in the institution using Robsons classification system as the starting point to find the contributing factors responsible for the caesarean section rates.Methods: This retrospective hospital-based study was conducted at MVJMC and RH. The study included all pregnant patients undergoing caesarean section during the period of one year from March 2023 to February 2024. All the data was entered into Microsoft excel, sheet, which was then classified according to Robson’s classification system.Results: In our study we noted that the highest percent of caesarean deliveries was noted among multigravida which contributed about 66.5 of the total caesarean deliveries and according to classification 35% of the caesarean deliveries was noted in group 3 with multiparous women of more than 37 weeks in spontaneous labour. Conclusions: Globally accepted Robsons classification should be used for regular audits among hospitals to curb the caesarean section and its associated maternal and perinatal complications in order to improve patient care.
背景:由于剖腹产率的上升,世界卫生组织(WHO)将罗布森分类系统作为评估和审核不同医院剖腹产率的全球标准,以降低剖腹产率和相关并发症,同时改善患者护理。本研究旨在对医院的剖腹产数量进行审计。目标是以罗伯逊分类系统为起点,对该院的剖腹产情况进行审核,找出导致剖腹产率的因素:这项以医院为基础的回顾性研究在MVJMC和RH进行。研究对象包括 2023 年 3 月至 2024 年 2 月这一年期间接受剖腹产手术的所有孕妇。所有数据均输入 Microsoft excel 表格,然后根据罗布森分类系统进行分类:我们在研究中发现,剖腹产比例最高的是多产妇,约占剖腹产总数的 66.5%,根据分类,35% 的剖腹产发生在第 3 组,即自然分娩 37 周以上的多产妇。结论全球公认的罗布森分类法应用于医院的定期审核,以遏制剖腹产及其相关的孕产妇和围产期并发症,从而改善对患者的护理。
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引用次数: 0
Comparison of ultrasound and computed tomography in the diagnosis of malignant ovarian tumours at tertiary care center 超声波和计算机断层扫描在三级医疗中心诊断恶性卵巢肿瘤中的比较
Pub Date : 2024-07-06 DOI: 10.18203/2320-1770.ijrcog20241952
Mozaffar Danish, Shreya Bhat, Asif Khursheed, M. S. Ahmad
Background: Accurate diagnosis of ovarian tumours is a diagnostic challenge. Multiple modes are used for the early detection of ovarian tumours. Early detection provides a survival advantage. Ultrasonography (USG), computed tomography (CT) and magnetic resonance imaging (MRI) are important imaging modalities in this regard. This study aims to compare the diagnostic accuracy of USG and CT imaging in the detection of malignant ovarian tumours.Materials: An observational cross-sectional study is conducted in the department of radiodiagnosis of Narayan medical college and hospital, Bihar over a period of 18 months from August 2021 to March 2024. Fifty-three patients with suspected ovarian malignancy who were not pregnant or had contraindications for administration of contrast media were included in the study. USG, CT and histopathology reports were compared for diagnostic accuracy with respect to different components.Results: Mean age of the patients was seen to be 49.6±13.8 years. Abdominal pain was the most common presentation Majority of the patients had vascular lesions with a well-differentiated margin, heterogenous enhancement and septations. USG and CT agree almost perfectly in, identifying septations, calcification, and in differentiating margin of the tumours and very poorly for the identification of lymphadenopathy. CT had better sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) when compared to USG for diagnosis of ovarian malignanciesConclusions: CT has superior diagnostic accuracy compared to USG for diagnosis of ovarian tumours. However, USG provides similar diagnostic accuracy for identifying septations, calcification, and in differentiating margins of tumours.
背景:准确诊断卵巢肿瘤是一项诊断挑战。卵巢肿瘤的早期检测采用多种模式。早期发现可提高生存率。在这方面,超声波(USG)、计算机断层扫描(CT)和磁共振成像(MRI)是重要的成像模式。本研究旨在比较 USG 和 CT 成像在检测恶性卵巢肿瘤方面的诊断准确性:这项观察性横断面研究在比哈尔邦纳拉扬医学院和医院放射诊断科进行,从 2021 年 8 月至 2024 年 3 月,为期 18 个月。研究纳入了 53 名疑似卵巢恶性肿瘤患者,这些患者均未怀孕或有使用造影剂的禁忌症。比较了 USG、CT 和组织病理学报告不同部分的诊断准确性:患者的平均年龄为(49.6±13.8)岁。腹痛是最常见的表现,大多数患者的血管病变边缘分化良好,有异质强化和间隔。USG 和 CT 在鉴别隔膜、钙化和区分肿瘤边缘方面几乎完全一致,但在鉴别淋巴结病方面却很不一致。与 USG 相比,CT 在诊断卵巢恶性肿瘤方面具有更好的敏感性、特异性、阳性预测值(PPV)和阴性预测值(NPV):与 USG 相比,CT 诊断卵巢肿瘤的准确性更高。然而,USG 在鉴别隔膜、钙化和区分肿瘤边缘方面的诊断准确性相似。
{"title":"Comparison of ultrasound and computed tomography in the diagnosis of malignant ovarian tumours at tertiary care center","authors":"Mozaffar Danish, Shreya Bhat, Asif Khursheed, M. S. Ahmad","doi":"10.18203/2320-1770.ijrcog20241952","DOIUrl":"https://doi.org/10.18203/2320-1770.ijrcog20241952","url":null,"abstract":"Background: Accurate diagnosis of ovarian tumours is a diagnostic challenge. Multiple modes are used for the early detection of ovarian tumours. Early detection provides a survival advantage. Ultrasonography (USG), computed tomography (CT) and magnetic resonance imaging (MRI) are important imaging modalities in this regard. This study aims to compare the diagnostic accuracy of USG and CT imaging in the detection of malignant ovarian tumours.\u0000Materials: An observational cross-sectional study is conducted in the department of radiodiagnosis of Narayan medical college and hospital, Bihar over a period of 18 months from August 2021 to March 2024. Fifty-three patients with suspected ovarian malignancy who were not pregnant or had contraindications for administration of contrast media were included in the study. USG, CT and histopathology reports were compared for diagnostic accuracy with respect to different components.\u0000Results: Mean age of the patients was seen to be 49.6±13.8 years. Abdominal pain was the most common presentation Majority of the patients had vascular lesions with a well-differentiated margin, heterogenous enhancement and septations. USG and CT agree almost perfectly in, identifying septations, calcification, and in differentiating margin of the tumours and very poorly for the identification of lymphadenopathy. CT had better sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) when compared to USG for diagnosis of ovarian malignancies\u0000Conclusions: CT has superior diagnostic accuracy compared to USG for diagnosis of ovarian tumours. However, USG provides similar diagnostic accuracy for identifying septations, calcification, and in differentiating margins of tumours.","PeriodicalId":14225,"journal":{"name":"International journal of reproduction, contraception, obstetrics and gynecology","volume":" 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141672910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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International journal of reproduction, contraception, obstetrics and gynecology
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