Camparative Study of the Physical Parameters in DMBA Induced Oral Carcinoma Rat Model and Herbal Extract FED Oral Carcinoma Rat Model

A. Shukla, V. K. Sharma
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Abstract

Cancer, a multifactorial disorder, arises due to defect in genetic makeup and exposure to unfavourable environmental conditions. Oral cancer, a life-threatening cancer worldwide, arises in the oral cavity due to ill-habits such as tobacco smoking and chewing. Monitoring body weight is an essential aspect of any preclinical study, including DMBA-induced oral carcinoma rat models and models with potential therapeutic interventions like Zingiber and piper feeding. Changes in body weight, feeding, water intake can provide valuable insights into the general health and physiological effects of the experimental conditions.
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DMBA 诱导的口腔癌大鼠模型和草药提取物 FED 口腔癌大鼠模型物理参数的对比研究
癌症是一种多因素疾病,是由于基因构成缺陷和暴露于不利的环境条件而导致的。口腔癌是全球范围内威胁生命的一种癌症,由于吸烟和咀嚼等不良习惯而发生在口腔。监测体重是任何临床前研究的一个重要方面,包括 DMBA 诱导的口腔癌大鼠模型和具有潜在治疗干预作用的模型,如喂食辛夷和蒌仁。体重、采食量和摄水量的变化可以为了解实验条件下的总体健康状况和生理影响提供有价值的信息。
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