Molecular dentistry: Polymerase chain reaction’s transformative role

Abstract

Molecular dentistry, propelled by advancements in techniques such as Polymerase Chain Reaction (PCR), has emerged as a promising frontier in dental research and practice. PCR has revolutionized the field of dentistry by enabling precise and sensitive detection of various oral pathogens, genetic markers associated with dental diseases, and host response factors. Its ability to amplify specific DNA sequences from minimal starting material has facilitated rapid and accurate diagnosis of dental infections, periodontal diseases, and genetic predispositions to oral conditions. Moreover, PCR-based methods have enhanced our understanding of the oral microbiome composition and its relationship with overall health. This review article aims to elucidate the transformative role of PCR in molecular dentistry by providing an overview of its applications, current developments, and future prospects.