{"title":"Synthesis and Evaluation of Antifungal Activity of Novel 1,3,4-Oxadiazole Derivatives","authors":"Aswathy Ramesh, R. Jat, R. Arunkumar","doi":"10.22270/ijmspr.v10i1.85","DOIUrl":null,"url":null,"abstract":"Here new eight derivatives of 1,3,4-oxadiazole were synthesised from salicylic acid and phenyl acetic acid by ring condensation mechanism. The synthesized derivatives were characterized and structures were confirmed by various spectral analysis. Antifungal activity studies revealed that Ox1, Ox2 and Ox4 exhibit promising activity.\nKeywords: 1,3,4-oxadiazole, antifungal activity, Disc diffusion method, MIC,","PeriodicalId":509624,"journal":{"name":"International Journal of Medical Sciences and Pharma Research","volume":" 11","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Medical Sciences and Pharma Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22270/ijmspr.v10i1.85","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Here new eight derivatives of 1,3,4-oxadiazole were synthesised from salicylic acid and phenyl acetic acid by ring condensation mechanism. The synthesized derivatives were characterized and structures were confirmed by various spectral analysis. Antifungal activity studies revealed that Ox1, Ox2 and Ox4 exhibit promising activity.
Keywords: 1,3,4-oxadiazole, antifungal activity, Disc diffusion method, MIC,
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