Deep Learning for Histopathological Image Analysis: A Convolutional Neural Network Approach to Colon Cancer Classification

Sarifah Agustiani, Yan Rianto
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Abstract

Colon cancer is a type of cancer that attacks the last part of the human digestive tract. Factors such as an unhealthy diet, low fiber consumption, and high animal protein and fat intake can increase the risk of developing this disease. Diagnosis of colon cancer requires sophisticated diagnostic procedures such as CT scan, MRI, PET scan, ultrasound, or biopsy, which are often time-consuming and require particular expertise. This study aims to classify colon cancer based on histopathological images using a dataset of 10,000 images. This data is divided into 7,950 images for training, 2,000 for testing, and 50 for validation, aiming to achieve effective generalization. The Convolutional Neural Network (CNN) method was applied in this research with a relatively shallow architecture consisting of 4 convolution layers, 2 fully connected layers, and 1 output layer. Research results were evaluated by looking at the accuracy value of 99.55%, precision value of 99.49%, recall of 99.59%, prediction experiments on several images, and loss and accuracy graphs to detect signs of overfitting. However, this research has limitations in determining hyperparameters and layer depth, which was only tested from 1 to 5 convolution layers. Therefore, there are still opportunities for further development, such as applying unique feature extraction before the classification process
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组织病理学图像分析的深度学习:结肠癌分类的卷积神经网络方法
结肠癌是一种侵犯人体消化道最后一部分的癌症。不健康的饮食、低纤维摄入量、高动物蛋白和脂肪摄入量等因素都会增加罹患这种疾病的风险。结肠癌的诊断需要 CT 扫描、核磁共振成像、正电子发射计算机断层扫描、超声波或活检等复杂的诊断程序,这些程序通常耗时较长,而且需要特殊的专业知识。本研究旨在使用一个包含 10,000 张图像的数据集,根据组织病理学图像对结肠癌进行分类。该数据集分为 7,950 张训练图像、2,000 张测试图像和 50 张验证图像,旨在实现有效的泛化。本研究采用了卷积神经网络(CNN)方法,其架构相对较浅,包括 4 个卷积层、2 个全连接层和 1 个输出层。研究结果通过准确率 99.55%、精确率 99.49%、召回率 99.59%、多幅图像的预测实验以及损失和准确率图进行评估,以发现过度拟合的迹象。不过,这项研究在确定超参数和层深度方面存在局限性,只测试了 1 到 5 个卷积层。因此,仍有进一步发展的机会,如在分类过程之前应用独特的特征提取。
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审稿时长
24 weeks
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