Wijdan Amer Ibrahim, Ekhlas Abdallah Hassan, W. Al-Zuhairi
{"title":"Characterization of Structural, Antimicrobial Activity, of Coriander Seed Oil","authors":"Wijdan Amer Ibrahim, Ekhlas Abdallah Hassan, W. Al-Zuhairi","doi":"10.52711/0974-360x.2024.00041","DOIUrl":null,"url":null,"abstract":"This study was aimed to investigate the structure of bioactive components of Coriander Seed Oil (CSO) and their antimicrobial effects. Initially, the structural examination was conducted using various spectroscopic techniques, such as FTIR, and UV-visible spectroscopy, which are important in determining substituents, functional groups, and the presence of conjugated double bonds in CSO. From the FTIR spectra, a variety of sharp, strong, and weak peaks were specified relating to the main components of Linalol, and Decenolin CSO. The results of UV-visible spectroscopy confirmed the presence of Linalool as a major compound, and conjugated double bonds were also found. Furthermore, anti- microbial activity of CSO was studied against various types of bacteria. Strong bacterial inhibitory effects were observed, especially against S. aureus, with an average inhibition zone of 18 mm. It was also found from the structural characterization of CSO that the existence of Linalol is responsible for potential antibacterial activity. The main observation of this work is that CSO has antimicrobial activity even against methicillin-resistant Staphylococcus aureus.","PeriodicalId":21141,"journal":{"name":"Research Journal of Pharmacy and Technology","volume":"388 4-6","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research Journal of Pharmacy and Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52711/0974-360x.2024.00041","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
引用次数: 0
Abstract
This study was aimed to investigate the structure of bioactive components of Coriander Seed Oil (CSO) and their antimicrobial effects. Initially, the structural examination was conducted using various spectroscopic techniques, such as FTIR, and UV-visible spectroscopy, which are important in determining substituents, functional groups, and the presence of conjugated double bonds in CSO. From the FTIR spectra, a variety of sharp, strong, and weak peaks were specified relating to the main components of Linalol, and Decenolin CSO. The results of UV-visible spectroscopy confirmed the presence of Linalool as a major compound, and conjugated double bonds were also found. Furthermore, anti- microbial activity of CSO was studied against various types of bacteria. Strong bacterial inhibitory effects were observed, especially against S. aureus, with an average inhibition zone of 18 mm. It was also found from the structural characterization of CSO that the existence of Linalol is responsible for potential antibacterial activity. The main observation of this work is that CSO has antimicrobial activity even against methicillin-resistant Staphylococcus aureus.
期刊介绍:
Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.