To Observe the patterns of Cutaneous Adverse Drug Reactions in a Tertiary health care teaching hospital in Hyderabad

Abstract

Cutaneous adverse drug reactions are very common and seen quite often during clinical practice. It is difficult to get a comprehensive list of the various types of drug reactions and their corresponding drug due to many cases going unreported. There is a possibility of a cutaneous drug reaction every time a new drug is introduced into the market. While most types of drug reactions are trivial and benign, there is always a possibility of the reaction attaining a more malignant nature. The diagnosis of a CADR is more often based on a clinical examination. However, in order to understand the full scope of the reaction it must be reported and studied. The pharmacovigilance programme takes into account the spontaneous nature of the cases and employs alogical approach based on clinical characteristics, chronologic factors, and generation of a focused differential diagnosis. Using study tools like Naranjo scale and Modified Hartwig and Siegel scale, a physician can easily determine the severity and causality of the drug reaction. After compiling the data, one can determine the trend of the morphology of these CADRs, and determine the most likely drug responsible for the reaction. The data obtained in this study is useful for helping the clinician in the proper identification, approach and treatment of a patient suffering from a cutaneous adverse rug reaction.