Medication adherence among hemodialysis patients: the impact of pharmacist-led motivational interviewing

Ganesh Sritheran Paneerselvam, Lee Kwing Chin Kenneth, Raja Ahsan Aftab, Roland Gamini Sirisinghe
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Abstract

Background: Significant proportion of haemodialysis (HD) patients fails to comply with their prescribed medication regimens, leading to poor health outcomes and survival rates. This highlights the need for interventions that improve medication adherence thereby leading to improved patient outcomes. Objectives: To evaluate the impact of motivational interviewing, a skilful clinical method to improve medication adherence among HD patients. Methods: A pre-post study was conducted prospectively among 63 HD patients at multicentre dialysis units. The recruited patients received three sessions of MI which helps in addressing patient beliefs around medication and overcome barriers for nonadherence. General medication adherence scale (GMAS) was used to evaluate the medication adherence among enrolled patients. An independent t-test was used to analyze the impact of MI in improving adherence among HD patients. In this study, the level of significance was 0.05. Results: A total of 63 patients (27 males and 36 females; mean age 48.5±13.9 years) were included in the study. While the mean of dialysis duration and number of medications was 7.7±6.0 years and 8.1±2.2 respectively. Paired t-test showed a significant increase in medication adherence score from a baseline for nonadherence domain of patient’s attitude and nonadherence domain of additional illness and pill overload at the end of the study (p<0.05). However, the non-adherence domain of financial constraints, was not statistically significant, p=0.507. Motivational interviewing was effective in increasing intrinsic positive attitude by resolving their ambivalence thus improving the adherence towards medication. Conclusion: This study emphasized that MI conducted by pharmacist effectively improves HD patients’ medication adherence. Healthcare professionals ought to employ this strategy in order to assist HD patients in better taking their medications.
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血液透析患者坚持用药的情况:药剂师主导的动机访谈的影响
背景:相当一部分血液透析(HD)患者未能遵照处方用药,导致健康状况和存活率低下。因此,有必要采取干预措施,提高患者的用药依从性,从而改善患者的治疗效果。研究目的评估动机访谈这种娴熟的临床方法对提高血液透析患者服药依从性的影响。方法在多中心透析单位的 63 名血液透析患者中开展了一项前瞻性研究。被招募的患者接受了三次多元智能治疗,这有助于消除患者的用药观念,克服不坚持用药的障碍。一般用药依从性量表(GMAS)用于评估入组患者的用药依从性。采用独立的 t 检验来分析多元智能对提高 HD 患者依从性的影响。本研究的显著性水平为 0.05。结果本研究共纳入 63 名患者(男性 27 人,女性 36 人;平均年龄为 48.5±13.9 岁)。透析时间和用药次数的平均值分别为 7.7±6.0 年和 8.1±2.2。配对 t 检验显示,在研究结束时,患者态度的非依从性领域以及附加疾病和药片过量的非依从性领域的用药依从性得分与基线相比均有显著提高(P<0.05)。然而,在经济限制这一不依从领域,P=0.507,无统计学意义。动机访谈通过解决患者的矛盾心理,有效提高了他们的内在积极态度,从而改善了他们的服药依从性。结论本研究强调,由药剂师进行的激励访谈能有效改善血液透析患者的服药依从性。医护人员应采用这一策略,以协助高清患者更好地服药。
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