Efficacy and Safety of Computed Tomography-Guided Percutaneous Balloon Compression under Local Anesthesia for Recurrent Trigeminal Neuralgia: A Prospective Study

Lulu Xi, Xiaohui Liu, Hongchen Shi, Wenbiao Han, Liqin Gao, Li Wang, Junpeng Liu, Yue Ren, Yuanyuan Du, Guangzhao Liu
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Abstract

Purpose. There are several ways to treat trigeminal neuralgia (TN); however, TN may recur after treatment. This study investigated the efficacy and safety of computed tomography (CT)-guided percutaneous balloon compression (PBC) under local anesthesia for treatment of recurrent trigeminal neuralgia. Patients and Methods. This is a prospective and nonrandomized controlled clinical study. Forty-eight patients with classical TN were scheduled to undergo PBC surgery at the pain department of our institution between January 2021 and June 2021. The patients were prospectively divided into an initial onset group, A (21 cases), and a recurrence group, B (27 cases). All surgeries were performed with CT guidance and under local anesthesia. Postoperative complications were also observed. Pain was assessed using the visual analog scale (VAS) and Barrow Neurological Institute (BNI) scale. Efficacy indices were evaluated at 3, 6, 12, and 18 months after surgery. Results. All participants reported complete pain relief at discharge. After 18 months of follow-up, the total effective rate of pain control was 89.5% (group A, 90.5%; group B, 88.8%). There was no significant difference in the BNI scores between the two groups before and after treatment. All patients had hypoesthesia on the affected side, and no severe complications such as diplopia, blindness, intracranial hemorrhage, or intracranial infection occurred. Conclusions. CT-guided PBC under local anesthesia is safe and effective for the treatment of recurrent TN and thus acts as an effective alternative for geriatric patients and those with high-risk factors.
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局部麻醉下计算机断层扫描引导的经皮球囊压迫治疗复发性三叉神经痛的有效性和安全性:前瞻性研究
目的。治疗三叉神经痛(TN)有多种方法,但治疗后可能复发。本研究探讨了在局部麻醉下使用计算机断层扫描(CT)引导的经皮球囊压迫术(PBC)治疗复发性三叉神经痛的有效性和安全性。患者和方法。这是一项前瞻性非随机对照临床研究。48例典型TN患者计划于2021年1月至2021年6月期间在我院疼痛科接受PBC手术。这些患者被前瞻性地分为初次发病组 A(21 例)和复发组 B(27 例)。所有手术均在 CT 引导和局部麻醉下进行。同时还观察了术后并发症。疼痛采用视觉模拟量表(VAS)和巴罗神经研究所(BNI)量表进行评估。疗效指数在术后 3、6、12 和 18 个月进行评估。结果。所有参与者在出院时均报告疼痛完全缓解。随访 18 个月后,疼痛控制总有效率为 89.5%(A 组为 90.5%;B 组为 88.8%)。两组患者在治疗前后的 BNI 评分无明显差异。所有患者的患侧均有麻木感,未出现复视、失明、颅内出血或颅内感染等严重并发症。结论在局部麻醉下进行CT引导下PBC治疗复发性TN安全有效,是老年患者和高危人群的有效选择。
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