Medial Femoral Condyle Periosteal Free Flap for Bone Coverage Following Debridement of Intermediate-Stage Osteoradionecrosis of the Jaw.

Michael J L Hurrell, David Leinkram, Murray J Stokan, Jonathan R Clark
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Abstract

Case report. Osteoradionecrosis (ORN) of the jaw is a potentially devastating consequence of head and neck irradiation. The progression of ORN can lead to loss of bone, teeth, soft tissue necrosis, pathologic fracture, and oro-cutaneous fistula. Reconstructive surgery has mostly been reserved for late-stage disease where segmental resections are frequently necessary. Evidence is emerging to support earlier treatment in the form of debridement in combination with soft tissue free flaps for intermediate-stage ORN. The authors present a case of a 76-year-old male with persistent Notani 2 ORN of the mandible, treated with surgical removal of all remaining mandibular teeth, transoral debridement of all necrotic mandibular bone, and bone coverage with a left medial femoral condyle (MFC) periosteal free flap based on the descending genicular artery. Treatment was uneventful both intraoperatively and postoperatively. Since surgery (15 mo) the patient has remained free from clinical and radiologic signs of ORN. The MFP periosteal free flap provided an excellent result with minimal surgical complexity and morbidity in this case. Such treatment at an intermediate stage likely results in a reduction in segmental resections, less donor site morbidity, less operative time, less overall treatment time, and possibly fewer postoperative complications compared with the status quo.
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用于中期颌骨坏死清创后骨覆盖的股骨髁内侧骨膜游离瓣
病例报告颌骨放射性坏死(ORN)是头颈部放射治疗的一种潜在破坏性后果。颌骨骨坏死的发展可导致骨、牙齿、软组织坏死、病理性骨折和口腔瘘。整形外科手术大多用于晚期疾病,因为晚期疾病经常需要进行节段性切除。越来越多的证据表明,清创结合软组织游离瓣的形式可以更早地治疗中期ORN。作者介绍了一例 76 岁男性下颌骨持续性诺坦尼 2 ORN 患者的病例,该患者接受了手术治疗,拔除了所有剩余的下颌牙齿,经口清创了所有坏死的下颌骨,并用基于降根动脉的左股骨内侧髁(MFC)骨膜游离瓣进行了骨覆盖。术中和术后的治疗都很顺利。手术后(15 个月),患者一直没有出现 ORN 的临床和影像学症状。在这个病例中,MFP 骨膜游离皮瓣取得了极佳的效果,手术复杂性和发病率都降到了最低。与现状相比,在中期阶段进行这种治疗可能会减少节段切除,降低供体部位的发病率,缩短手术时间,缩短整体治疗时间,并可能减少术后并发症。
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