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Auricular Reconstruction With Ultra-Short Dental Implant-retained Prosthesis: A Case Report on Virtual Planning Software and 3D Surgical Guides. 使用超短种植体修复体进行耳廓重建:关于虚拟规划软件和 3D 手术导板的病例报告。
Pub Date : 2024-09-17 DOI: 10.1097/scs.0000000000010631
Gun Song,Ji-Su Park,Seunggon Jung
Auricular reconstruction in traumatic patients needs a more diverse and in-depth approach as the graft site may not be available for autologous graft. The implant-retained auricular prosthesis has shown satisfying outcomes for those patients who have lost their auricle due to congenital or acquired reasons. When osseointegrated auricular implants are not available, dental implant and implant-planning software can provide safe, reliable, and predictable outcomes. In this case, a 30-year-old patient who lost the right auricle due to trauma underwent auricular reconstruction with implant retained prosthesis by using an ultra-short dental implant and surgical guide which was prefabricated virtually with dental implant software.
外伤患者的耳廓重建需要更加多样化和深入的方法,因为移植部位可能无法进行自体移植。对于因先天或后天原因失去耳廓的患者,植入式耳廓假体已显示出令人满意的效果。当无法使用骨结合耳廓植入物时,牙科植入物和植入物规划软件可以提供安全、可靠和可预测的结果。在本病例中,一名因外伤失去右耳廓的 30 岁患者通过使用超短牙科种植体和手术导板,接受了种植体固位修复的耳廓重建手术。
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引用次数: 0
Strategy of Severe Pneumonia and Management of Related Complications After Autogenous Cartilage Microtia Reconstruction. 自体软骨小耳畸形修复术后重症肺炎的应对策略及相关并发症的处理。
Pub Date : 2024-09-17 DOI: 10.1097/scs.0000000000010491
Jingjing Ruan,Qingqian Wei,Jiajia Wu,Zeman Chen,Xuehong Liu,Na Liu
Since the pioneering use of autologous costal cartilage for microtia reconstruction, significant progress has been made in treating microtia, effectively improving patients' quality of life and reducing their psychological burden. Cartilage auricle reconstruction is the primary treatment, but many postoperative complications can occur. Common postoperative complications include infection and hematoma at the recipient site, pleural tears at the donor site, and thoracic scoliosis. Among these, severe postoperative pneumonia is a rare but potentially fatal complication. This study presents a case of severe pneumonia after auricular reconstruction with autologous cartilage. It details the complications associated with autologous cartilage microtia reconstruction, especially pulmonary complications, and suggests a possible relationship between pulmonary complications and auricular reconstruction using cartilage.
自开创性地使用自体肋软骨重建小耳症以来,小耳症的治疗取得了重大进展,有效改善了患者的生活质量,减轻了他们的心理负担。软骨耳廓重建是主要的治疗方法,但术后可能出现许多并发症。常见的术后并发症包括受体部位的感染和血肿、供体部位的胸膜撕裂以及胸廓侧弯。其中,术后重症肺炎是一种罕见但可能致命的并发症。本研究介绍了一例使用自体软骨进行耳廓重建术后的重症肺炎病例。它详细介绍了与自体软骨小耳畸形重建相关的并发症,尤其是肺部并发症,并提出了肺部并发症与使用软骨进行耳廓重建之间可能存在的关系。
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引用次数: 0
Effect of Surgical Timing to Dental Health in Secondary Alveolar Bone Grafting: Three-Dimensional Outcomes. 二次牙槽骨移植中手术时机对牙齿健康的影响:三维结果。
Pub Date : 2024-09-17 DOI: 10.1097/scs.0000000000010665
Donghwan Kwon,Youngmin Shin,Taehee Jo,Jaehoon Choi,Junhyung Kim,Woonhyeok Jeong
BACKGROUNDThere are various opinions on the optimal timing for performing secondary alveolar bone grafting (SABG). This study compared dental health and 3-dimensional outcomes according to the timing of SABG surgery.PATIENTS AND METHODSA retrospective chart review was performed in patients who underwent SABG between January 1996 and October 2020. Patients were divided into early SABG (6-8 y old) and traditional SABG (9-13 y old) groups. The final dental survival of the lateral incisor and canine teeth, survival of the bone graft, and maxillary growth were analyzed using plain radiographs and computed tomography with a 3-dimensional volumetric analysis tool.RESULTSThirty-six patients were divided into an early group (15 patients) and a traditional group (21 patients). Five patients had bilateral cleft lip, and 26 patients had unilateral cleft lip and palate; therefore, 36 alveolar clefts were analyzed in this study. Lateral incisor survival was significantly greater in the early group than in the traditional group (60% vs. 23.5%; P<0.05). Compared with that in the traditional group, graft success in the early group was greater (80% vs. 57.1%; P<0.05). Three-dimensional volumetric analysis revealed superior bone graft efficiency in the early group compared with the traditional group (55.2 vs. 38.5%; P<0.05). There was no significant difference in maxillary growth between the 2 groups.CONCLUSIONSIn our study, superior dental and clinical outcomes were observed in the early SABG group without any long-term complications or maxillary retrusion. Our institution cautiously indicated that SABG could be performed at an age earlier than the existing SABG performed after 9 years old.
背景关于二次牙槽骨移植术(SABG)的最佳手术时机众说纷纭。本研究根据 SABG 手术时机比较了牙齿健康状况和三维结果。患者被分为早期 SABG 组(6-8 岁)和传统 SABG 组(9-13 岁)。结果36例患者被分为早期组(15例)和传统组(21例)。5 名患者为双侧唇裂,26 名患者为单侧唇腭裂,因此本研究分析了 36 个牙槽隙。早期组的侧切牙存活率明显高于传统组(60% 对 23.5%;P<0.05)。与传统组相比,早期组的移植成功率更高(80% 对 57.1%;P<0.05)。三维容积分析显示,早期组的骨移植效率高于传统组(55.2% 对 38.5%;P<0.05)。结论 在我们的研究中,早期 SABG 组的牙科和临床疗效均优于传统组,且无任何长期并发症或上颌后缩。本机构谨慎地指出,SABG手术的年龄可以早于现有的9岁以后进行的SABG手术。
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引用次数: 0
Goldenhar Syndrome Complicated by Hemifacial Microsomia and Unilateral Cleft Palate Absence. 戈登哈尔综合征并发下颌畸形和单侧腭裂。
Pub Date : 2024-09-17 DOI: 10.1097/scs.0000000000010555
Hao Chen,Weimin Shen
Goldenhar syndrome, also known as oculo-auriculo-vertebral spectrum (OAVS) or hemifacial microsomia (HFM), is characterized by developmental anomalies in structures such as the eyes, ears, upper jaw, lower jaw, upper palate, and spine. The facial abnormalities, stemming predominantly from branchial arch malformation, are sometimes categorized as the first and second branchial arch syndromes. Its incidence is estimated to be ∼1 in 3500. Here, the authors present a case of Goldenhar syndrome in a male infant at the age of 10 months, showcasing a particularly unique manifestation of cleft palate, for which we employed myomucosal flap reconstruction of the soft palate.
戈登哈尔综合征(Goldenhar Syndrome)又称眼耳畸形(occulo-auriculo-vertebral spectrum,OAVS)或半面神经小畸形(hemifacial microsomia,HFM),其特征是眼睛、耳朵、上颚、下颚、上腭和脊柱等结构的发育异常。面部畸形主要源于支弓畸形,有时被归类为第一和第二支弓综合征。据估计,其发病率约为 3500 分之 1。在此,作者介绍了一例 10 个月大的戈登哈尔综合征男婴,这是一种特别独特的腭裂表现,我们采用了肌粘膜瓣重建软腭。
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引用次数: 0
Qualitative Research on the Causes of Kinesiophobia in Postoperative Cerebellar Tumor Patients. 小脑肿瘤术后患者运动恐惧症成因的定性研究
Pub Date : 2024-09-17 DOI: 10.1097/scs.0000000000010420
Xin Xu,Wei Wang,Xiuqin Feng
OBJECTIVETo understand the causes of kinesiophobia in postoperative patients with cerebellar tumors, and to provide the basis for early rehabilitation regimen.METHODSUsing the objective sampling method, 16 postoperative cerebellar tumor patients were extracted for semi-structured interviews. Data was analyzed using the Colaizzi 7-step method, and the theme was refined.RESULTSThe causes of kinesiophobia in postoperative cerebellar tumor patients were summarized into 4 themes: Excessive vigilance to self-state. Increased pain sensitivity and fear of dizziness were regarded as threat signals, which brought excessive burden on the current therapeutic regimen. Uncertainty of early rehabilitation. Lack of cognition, uncertainty effect of early rehabilitation, and insufficient exercise of self-efficacy. Psychological stress and avoidant emotion. Economic pressure and avoidant emotion ran out of control. Vulnerable support system. Deficient in professional technique, family, and social support.CONCLUSIONThe kinesiophobia in postoperative cerebellar tumor patients is composed of multiple factors. Medical staff are supposed to help patients establish a correct perception of disease status. The information on early rehabilitation needs to be transmitted continually. To promote patients to participate in early rehabilitation activities energetically, it is vital to keep a high level of rehabilitation effect expectation, increased self-exercise efficiency, psychological intervention, and strong multi-party cooperation in an improved social support system.
目的了解小脑肿瘤术后患者运动恐惧的原因,为早期康复治疗提供依据。方法采用客观抽样法,抽取16名小脑肿瘤术后患者进行半结构式访谈。结果小脑肿瘤术后患者运动恐惧的原因归纳为 4 个主题:对自我状态的过度警惕。疼痛敏感性的增加和对头晕的恐惧被视为威胁信号,这给当前的治疗方案带来了过重的负担。早期康复的不确定性。缺乏认知,早期康复的不确定性影响,自我效能感锻炼不足。心理压力和回避情绪。经济压力和逃避情绪失控。脆弱的支持系统。结论 小脑肿瘤术后患者的运动恐惧是由多种因素造成的。医务人员应帮助患者建立对疾病状态的正确认识。早期康复的信息需要不断传递。要促进患者积极主动地参与早期康复活动,保持高度的康复效果预期、提高自我锻炼效率、心理干预、改善社会支持系统的多方有力合作至关重要。
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引用次数: 0
A Subunit-Based Concept for Preoperative Design of the Cauliflower Ear. 基于亚单位的菜花耳术前设计理念
Pub Date : 2024-09-17 DOI: 10.1097/scs.0000000000010634
Xu Ma,Xinyue Dai,Dapeng Zhang,Zenghui Xiong,Bingyu Wang,Jiajun Li,Guofeng Liu
PURPOSECauliflower ear is an ear deformity caused by a closed ear injury with varying severity. Several studies on the systematic reconstruction of cauliflower ear have been reported. Here, the authors aim to introduce a simplified subunit-based reconstruction concept for the cauliflower ear.METHODSThe authors retrospectively analyzed all patients who underwent surgery to repair cauliflower ear in our department from April 2021 to April 2023. Patients' demographic information, clinical characteristics, and outcomes were recorded. All patients were followed up for 1 year.TECHNIQUEThe authors assessed each subunit of the cauliflower ear in sequence in terms of the change in size and shape and decided whether tissue removal or grafting is needed. The surgical design was obtained by a combination of all subunits.RESULTSThe authors included a total of 5 patients with mild and moderate cauliflower ear repaired by the subunit-based method. The shape of all the involved ear subunits of our patients was almost restored. No patient needed the use of cartilage grafts and flaps. The authors summarized 5 common subunits with deformity: helix, scaphoid fossa, antihelix crura and triangular fossa, antihelix body, and concha. The pathology results reported a keloid in 1 case. All patients reported no recurrence and were satisfied with the surgery after 1 year.CONCLUSIONSThe authors reported a simplified subunit-based method of preoperative evaluation and design of cauliflower ear, as a new alternative option to complement the current clinical strategies. The authors also reported the first case of a keloid in cauliflower ear.
目的菜花耳是一种由严重程度不一的耳部闭合性损伤引起的耳部畸形。关于系统性重建菜花耳的研究已有多篇报道。方法作者回顾性分析了 2021 年 4 月至 2023 年 4 月期间在我科接受手术修复菜花耳的所有患者。记录了患者的人口统计学信息、临床特征和结果。作者依次评估了菜花耳各亚单位的大小和形状变化,并决定是否需要切除或移植组织。结果作者共收治了 5 例轻度和中度菜花耳患者,采用基于亚单位的方法进行了修复。患者所有受累耳亚单位的形状几乎都得到了恢复。没有患者需要使用软骨移植和皮瓣。作者总结了 5 个常见的畸形亚单位:螺旋体、肩胛窝、反螺旋体嵴和三角窝、反螺旋体和圆锥体。病理结果显示,1 例患者出现瘢痕疙瘩。结论作者报告了一种简化的基于亚单位的菜花耳术前评估和设计方法,作为目前临床策略的一种新的替代选择。作者还报告了首例菜花耳瘢痕疙瘩病例。
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引用次数: 0
Middle Meningeal Artery Embolization Reduces the Recurrence Rate of Chronic Subdural Hematoma: A Propensity Score Matching Analysis. 脑膜中动脉栓塞术可降低慢性硬膜下血肿的复发率:倾向得分匹配分析。
Pub Date : 2024-09-17 DOI: 10.1097/scs.0000000000010650
Ying Wang,Wei Wang,Qinghua Huang,Wei Yan,Meijuan Lan
To evaluate the effect of middle meningeal artery embolization (MMAE) on chronic subdural hematoma (CSDH). The authors enrolled consecutive patients with CSDH who underwent burr hole craniostomy (BHC) between January 2020 and February 2023. The primary outcome was recurrence rate, defined as an increase of hematoma width on imaging compared with the immediate postoperative imaging at a 3-month follow-up. Secondary outcomes included the rate of complications and adverse prognosis. Cohorts were balanced using 1:2 propensity score matching (PSM). A total of 271 patients were eligible for this study and divided into the MMAE group (n=23) and the BHC group (n=205). Compared with the BHC group, there was more use of anticoagulant or antiplatelet medication (47.8% vs 22.4%, P=0.008), bilateral hematoma (19.5% vs 19.5%, P=0.043), and hematoma with septations (47.8% vs 21.5%, P=0.005) in the MMAE group. After PSM, 64 cases were finally successfully matched. The logistic analysis result showed that MMAE was associated with the decreased recurrence rate of CSDH in the cohort after PSM (OR 0.072, 95% CI: 0.322~0.746, P=0.028) but not with the improved clinical prognosis (OR 0.065, 95% CI: 0.533~4.786, P=0.562). MAAE has a positive therapeutic effect on reducing the recurrence rate of CSDHs as an adjunct postoperative treatment after burr hole surgery.
目的:评估脑膜中动脉栓塞术(MMAE)对慢性硬膜下血肿(CSDH)的影响。作者连续招募了 2020 年 1 月至 2023 年 2 月间接受毛细孔开颅术(BHC)的 CSDH 患者。主要结果是复发率,即与术后3个月随访时的即时成像相比,血肿宽度增加。次要结果包括并发症发生率和不良预后。采用1:2倾向评分匹配法(PSM)对组群进行平衡。共有 271 名患者符合研究条件,分为 MMAE 组(23 人)和 BHC 组(205 人)。与 BHC 组相比,MMAE 组更多使用抗凝或抗血小板药物(47.8% vs 22.4%,P=0.008)、双侧血肿(19.5% vs 19.5%,P=0.043)和血肿伴间隔(47.8% vs 21.5%,P=0.005)。经过 PSM,64 例病例最终配型成功。逻辑分析结果显示,MMAE 与 PSM 后队列中 CSDH 复发率的降低相关(OR 0.072,95% CI:0.322~0.746,P=0.028),但与临床预后的改善无关(OR 0.065,95% CI:0.533~4.786,P=0.562)。MAAE作为毛细孔手术后的术后辅助治疗手段,对降低CSDH的复发率具有积极的治疗作用。
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引用次数: 0
The Incidence and Morphology of Deformational Plagiocephaly in Unicoronal Synostosis. 单颅骨并合症畸形长头畸形的发生率和形态学。
Pub Date : 2024-09-17 DOI: 10.1097/scs.0000000000010579
Hyok Jun Kwon,Roland Deek,Lachlan D M Farmer,Mark H Moore
It has been our observation that unicoronal synostosis and deformational plagiocephaly (DP) are not mutually exclusive. The incidence and phenotypical manifestations of a patient presenting with both conditions have not been studied previously. The authors performed a retrospective review of patients presenting with unicoronal synostosis, examining their 3DCT scans for the presence of DP and assessing their endocranial and orbital morphology. The authors found that 38.4% of patients with unicoronal synostosis also have DP. Ipsilateral DP is less common than contralateral DP, but these patients tend to have a delayed presentation due to a reduction in forehead asymmetry corresponding to the parallelogram deformity. Regardless, DP has no impact on the endocranial nor orbital morphology in unicoronal synostosis.
据我们观察,单冠突触症和畸形性长头畸形(DP)并不相互排斥。关于同时患有这两种疾病的患者的发病率和表型表现,此前尚未进行过研究。作者对单冠突触症患者进行了回顾性研究,检查了他们的三维 CT 扫描是否存在 DP,并评估了他们的颅内和眼眶形态。作者发现,38.4% 的单侧突触症患者同时患有 DP。同侧DP比对侧DP少见,但由于平行四边形畸形导致前额不对称程度降低,这些患者往往会延迟发病。无论如何,DP 对单侧突眼的颅内和眼眶形态都没有影响。
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引用次数: 0
Conservative Treatment of Chalazion in Pediatric Patients. 小儿霰粒肿的保守治疗。
Pub Date : 2024-09-17 DOI: 10.1097/scs.0000000000010644
Seung Ahn Yang,Christopher B Chambers,Min Seung Kang,Jung Hyo Ahn
This study aims to assess the effectiveness of conservative treatment for chalazion in pediatric patients. The authors retrospectively reviewed 101 chalazions in 91 children aged younger than 15 years at the authors' clinic. Patients were divided into 3 groups by their ages at the time of conservative or surgical treatment: 30 patients aged 2 and under (group A), 38 patients aged 3 to 6 (group B), and 23 patients aged 7 to 15 (group C). Initially, conservative treatment was administered, then incision and curettage were performed if it proved ineffective. Data included sex, age, number of lesions, position of lesions, size of lesions, time to resolution after treatment, and presence of complications for each group; comparative analysis was conducted. The success rate of conservative treatment was 85.7% (78/91): 96.7% (29/30) in group A, 86.8% (33/38) in group B, and 69.7% (16/23) in group C (P = 0.022). The mean age of the patients and the mean lesion size showed a significant difference between the conservative group and the surgery group (P = 0.047 and 0.009, respectively). Conservative treatment of chalazion is an effective first-line treatment option for uncomplicated and small chalazion in pediatric patients. The authors should consider starting patients on a trial of conservative therapy versus invasive therapy based on the size of the lesion, the duration of conservative treatment, and age.
本研究旨在评估儿科霰粒肿保守治疗的有效性。作者回顾性研究了作者诊所中 91 名 15 岁以下儿童的 101 例霰粒肿。根据患者接受保守或手术治疗时的年龄将其分为三组:2岁及以下的患者有30人(A组),3至6岁的患者有38人(B组),7至15岁的患者有23人(C组)。最初采用保守治疗,如果效果不佳,则进行切开和刮除术。数据包括各组患者的性别、年龄、病灶数量、病灶位置、病灶大小、治疗后消退时间以及是否出现并发症;并进行了比较分析。保守治疗的成功率为 85.7%(78/91):A组为96.7%(29/30),B组为86.8%(33/38),C组为69.7%(16/23)(P=0.022)。保守治疗组和手术治疗组患者的平均年龄和平均病灶大小有显著差异(P = 0.047 和 0.009)。对于无并发症的小儿霰粒肿,保守治疗是有效的一线治疗方案。作者应根据病变的大小、保守治疗的持续时间和年龄,考虑让患者开始接受保守治疗与侵入性治疗的对比试验。
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引用次数: 0
Platelet-Rich Plasma in the Prevention and Treatment of Medication-Related Osteonecrosis of the Jaw: A Systematic Review and Meta-Analysis. 富血小板血浆在预防和治疗药物相关性颌骨坏死中的应用:系统回顾与元分析》。
Pub Date : 2024-09-17 DOI: 10.1097/scs.0000000000010664
Marwan H Aljohani
OBJECTIVESMedication-related osteonecrosis of the jaw (MRONJ) is a significant complication associated with bisphosphonates, impacting jaw osteoclasts, and causing altered bone remodelling. Prevention involves stabilizing systemic pathology, considering antiresorptive therapies, and exploring platelet-rich fibrin (PRF) for wound healing and tissue regeneration. The study aims to assess the efficacy of PRF in MRONJ treatment and highlight research gaps for more robust investigations.METHODSFollowing PRISMA and MOOSE guidelines, this systematic review and meta-analysis included English publications from 2013 to 2023, employing a systematic search in databases such as MEDLINE, Scopus, and Web of Science. Quality assessment used the Cochrane Collaboration's tool and the NOS, with the main meta-analysis concentrating on PRF-treated MRONJ cases, assessing resolution rates, and prioritizing healing outcomes and infection absence as primary endpoints.RESULTSThe study, encompassing 11 articles and 480 participants with MRONJ, demonstrated that in stage 1 procedures, PRF significantly outperformed conventional medical treatments (OR: 2.93, 95% CI: 1.54-5.59, P=0.001), particularly at the mandible site (OR: 1.65, 95% CI: 0.86-3.17, P=0.13). PRF also exhibited significantly superior healing outcomes compared with conventional medical treatments (OR: 4.45, 95% CI: 1.58-12.53, P=0.005), supporting its consideration as a valuable alternative in specific MRONJ management scenarios.CONCLUSIONThis study highlights PRF's effectiveness in early MRONJ interventions and specific anatomic sites, despite acknowledged limitations, emphasizing the need for further research, and supporting its consideration in MRONJ surgical management.
目的与药物相关的颌骨骨坏死(MRONJ)是与双磷酸盐相关的一种重要并发症,会影响颌骨破骨细胞并导致骨重塑改变。预防措施包括稳定全身病理学、考虑抗骨质吸收疗法以及探索富血小板纤维蛋白(PRF)用于伤口愈合和组织再生。本研究旨在评估 PRF 在 MRONJ 治疗中的疗效,并突出研究空白,以便进行更有力的调查。方法本系统综述和荟萃分析遵循 PRISMA 和 MOOSE 指南,纳入了 2013 年至 2023 年的英文出版物,并在 MEDLINE、Scopus 和 Web of Science 等数据库中进行了系统检索。质量评估采用 Cochrane 协作组织的工具和 NOS,主要荟萃分析集中于 PRF 治疗的 MRONJ 病例,评估痊愈率,并将痊愈结果和无感染作为主要终点。结果该研究包括 11 篇文章和 480 名 MRONJ 患者,结果表明,在第一阶段手术中,PRF 明显优于传统的药物治疗(OR:2.93,95% CI:1.54-5.59,P=0.001),尤其是在下颌骨部位(OR:1.65,95% CI:0.86-3.17,P=0.13)。尽管存在公认的局限性,但本研究强调了 PRF 在早期 MRONJ 干预和特定解剖部位的有效性,强调了进一步研究的必要性,并支持在 MRONJ 手术管理中考虑使用 PRF。
{"title":"Platelet-Rich Plasma in the Prevention and Treatment of Medication-Related Osteonecrosis of the Jaw: A Systematic Review and Meta-Analysis.","authors":"Marwan H Aljohani","doi":"10.1097/scs.0000000000010664","DOIUrl":"https://doi.org/10.1097/scs.0000000000010664","url":null,"abstract":"OBJECTIVESMedication-related osteonecrosis of the jaw (MRONJ) is a significant complication associated with bisphosphonates, impacting jaw osteoclasts, and causing altered bone remodelling. Prevention involves stabilizing systemic pathology, considering antiresorptive therapies, and exploring platelet-rich fibrin (PRF) for wound healing and tissue regeneration. The study aims to assess the efficacy of PRF in MRONJ treatment and highlight research gaps for more robust investigations.METHODSFollowing PRISMA and MOOSE guidelines, this systematic review and meta-analysis included English publications from 2013 to 2023, employing a systematic search in databases such as MEDLINE, Scopus, and Web of Science. Quality assessment used the Cochrane Collaboration's tool and the NOS, with the main meta-analysis concentrating on PRF-treated MRONJ cases, assessing resolution rates, and prioritizing healing outcomes and infection absence as primary endpoints.RESULTSThe study, encompassing 11 articles and 480 participants with MRONJ, demonstrated that in stage 1 procedures, PRF significantly outperformed conventional medical treatments (OR: 2.93, 95% CI: 1.54-5.59, P=0.001), particularly at the mandible site (OR: 1.65, 95% CI: 0.86-3.17, P=0.13). PRF also exhibited significantly superior healing outcomes compared with conventional medical treatments (OR: 4.45, 95% CI: 1.58-12.53, P=0.005), supporting its consideration as a valuable alternative in specific MRONJ management scenarios.CONCLUSIONThis study highlights PRF's effectiveness in early MRONJ interventions and specific anatomic sites, despite acknowledged limitations, emphasizing the need for further research, and supporting its consideration in MRONJ surgical management.","PeriodicalId":501649,"journal":{"name":"The Journal of Craniofacial Surgery","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142253772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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The Journal of Craniofacial Surgery
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