[Microbial colonization of carious progression stages in the dentin of human teeth--a controlled therapeutic study].

S Kneist, R Heinrich, W Künzel
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Abstract

In a controlled clinical trial the microflora of the cavity floor of 70 primary lower second molars with deep carious lesions were determined after caries excavation. The teeth were extracted and pulpal status was evaluated after 16 months of microbial control to determine the etiopathogenic role of germs for carious progression in dentine. 67% of the primary molars were free from pulpal inflammations. Soft carious dentine were significantly higher infected than the clinically acceptable hard dentine. Only in 40% of the cavity floors the microorganisms were eliminated. In the infected teeth basophilic microorganisms were found in causality to pulps without inflammations; acidogenic streptococci and lactobacilli were involved in pulpal inflammations. Results indicate that the latter genera of microorganisms are of etiological significance for carious progression in dentine.

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[微生物在人类牙本质龋齿进展阶段的定植——一项对照治疗研究]。
对70颗深龋的初生下第二磨牙进行了牙槽菌群的测定。拔牙后进行16个月的微生物控制,评估牙髓状态,以确定细菌对牙本质龋齿进展的致病作用。67%的初生磨牙无牙髓炎症。软质牙本质感染明显高于临床可接受的硬质牙本质。只有40%的空腔地板微生物被清除。在感染牙中发现嗜碱性微生物与无炎症的牙髓有因果关系;致酸性链球菌和乳酸菌参与了牙髓炎症。结果表明,后一类微生物对牙本质龋病的发展具有病原学意义。
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