Subarachnoid haemorrhage in a newly diagnosed Chronic Myelogenous Leukemia patient: A diagnostic challenge

Q3 Medicine Ethiopian Medical Journal Pub Date : 2024-04-15 DOI:10.4314/emj.v62i2.7
Zekewos Demissie, Brook Alemayehu, Nahom Zemedkun, Fisihatsion Tadesse
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Abstract

Chronic Myelogenous Leukemia (CML) is a myeloproliferative neoplasm with a prevalence of 1 to 2 cases per 100,000 adult population. In chronic myelogenous leukemia (CML), central nervous system (CNS) manifestations are reported in the advanced phase of the disease due to leukostasis, thrombosis, bleeding, infection, and CNS infiltration. However, CNS manifestations are uncommon in the chronic phase (CP) of CML, and an alternate diagnosis should be considered for symptomatic patients. We report a ruptured aneurysmal subarachnoid hemorrhage (SAH) as an initial presentation in a previously undetected CML patient.
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新诊断的慢性粒细胞白血病患者出现蛛网膜下腔出血:诊断难题
慢性粒细胞白血病(CML)是一种骨髓增生性肿瘤,发病率为每 10 万成年人中有 1 到 2 例。据报道,在慢性粒细胞白血病(CML)的晚期,由于白细胞凝集、血栓形成、出血、感染和中枢神经系统浸润,会出现中枢神经系统(CNS)表现。然而,中枢神经系统表现在慢性骨髓增生性白血病(CML)的慢性期(CP)并不常见,有症状的患者应考虑其他诊断。我们报告了一名先前未被发现的慢性骨髓性白血病患者初次出现动脉瘤破裂性蛛网膜下腔出血(SAH)。
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来源期刊
Ethiopian Medical Journal
Ethiopian Medical Journal Medicine-Medicine (all)
CiteScore
0.40
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0.00%
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0
期刊介绍: The Ethiopian Medical Journal (EMJ) is the official Journal of the Ethiopian Medical Association (EMA) and devoted to the advancement and dissemination of knowledge pertaining to the broad field of medicine in Ethiopia and other developing countries. Prospective contributors to the Journal should take note of the instructions of Manuscript preparation and submission to EMJ as outlined below.
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