Referral practices and treatment of obstructive sleep apnea in pregnancies with obesity

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-04-01 DOI:10.1002/osp4.754
S. Warhurst, E. Georgousopoulou, Farah Sethna, Hsin‐Chia Huang
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Abstract

Abstract Objective Obstructive sleep apnea (OSA) affects maternal and neonatal health during pregnancy. This study aimed to identify characteristics and comorbidities associated with sleep clinic referral in high‐risk pregnancies with Body Mass Index (BMI) ≥35 kg/m2. Method Retrospective cohort study for individuals in a high‐risk pregnancy clinic at a tertiary Australian hospital from 1 January to 31 December 2020 with BMI≥35 kg/m2. The primary outcome measure was sleep clinic referral. Exposure data included multiple comorbidities and formal tools (Epworth Sleepiness Scale and STOP‐BANG). Multivariable analysis was used to identify factors associated with referral. Descriptive data on barriers to diagnosis and treatment were collected. Results Of 161 pregnant individuals, 38.5% were screened using formal tools and 13.7% were referred to sleep clinic. Having STOP‐BANG performed was associated with sleep clinic referral (Odds Ratio: 18.04, 95% Confidence Interval:4.5–71.7, p < 0.001). No clinical characteristics were associated with the likelihood of performing STOP‐BANG. The COVID‐19 pandemic was a treatment barrier for three individuals. Conclusions Current screening practices identify pregnant individuals with the highest pre‐test probability of having OSA. Future research should evaluate real‐world strategies to improve identification and management in this high‐risk population.
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肥胖孕妇阻塞性睡眠呼吸暂停的转诊和治疗方法
摘要 目的 阻塞性睡眠呼吸暂停(OSA)会影响孕期孕妇和新生儿的健康。本研究旨在确定体重指数(BMI)≥35 kg/m2的高危妊娠中与睡眠门诊转诊相关的特征和合并症。方法 对 2020 年 1 月 1 日至 12 月 31 日在澳大利亚一家三甲医院高危妊娠门诊就诊、体重指数≥35 kg/m2 的患者进行回顾性队列研究。主要结果指标是睡眠门诊转诊情况。暴露数据包括多种合并症和正式工具(埃普沃斯嗜睡量表和STOP-BANG)。多变量分析用于确定与转诊相关的因素。还收集了有关诊断和治疗障碍的描述性数据。结果 在 161 名孕妇中,38.5% 使用正规工具进行了筛查,13.7% 转诊至睡眠诊所。进行STOP-BANG检查与睡眠诊所转诊有关(比值比:18.04,95% 置信区间:4.5-71.7,p < 0.001)。临床特征与实施 STOP-BANG 的可能性无关。COVID-19大流行是三个人的治疗障碍。结论 目前的筛查方法能识别出检查前患有 OSA 可能性最高的孕妇。未来的研究应评估现实世界中的策略,以改善对这一高风险人群的识别和管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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