Longitudinal invariance of the Patient Health Questionnaire-9 among patients receiving pharmacotherapy for major depressive disorder: A secondary analysis of clinical trial data.

IF 3.3 2区 心理学 Q1 PSYCHOLOGY, CLINICAL Psychological Assessment Pub Date : 2024-08-01 Epub Date: 2024-05-16 DOI:10.1037/pas0001317
Daniel J Reis, Adam R Kinney, Jeri E Forster, Kelly A Stearns-Yoder, Julie A Kittel, Amanda E Wood, David W Oslin, Lisa A Brenner, Joseph A Simonetti
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Abstract

Comparing self-reported symptom scores across time requires longitudinal measurement invariance (LMI), a psychometric property that means the measure is functioning identically across all time points. Despite its prominence as a measure of depression symptom severity in both research and health care, LMI has yet to be firmly established for the Patient Health Questionnaire-9 depression module (PHQ-9), particularly over the course of antidepressant pharmacotherapy. Accordingly, the objective of this study was to assess for LMI of the PHQ-9 during pharmacotherapy for major depressive disorder. This was a secondary analysis of data collected during a randomized controlled trial. A total of 1,944 veterans began antidepressant monotherapy and completed the PHQ-9 six times over 24 weeks of treatment. LMI was assessed using a series of four confirmatory factor analysis models that included all six time points, with estimated parameters increasingly constrained across models to test for different aspects of invariance. Root-mean-square error of approximation of the chi-square difference test values below 0.06 indicated the presence of LMI. Exploratory LMI analyses were also performed for separate sex, age, and race subgroups. Root-mean-square error of approximation of the chi-square difference test showed minimal change in model fits during invariance testing (≤ 0.06 for all steps), supporting full LMI for the PHQ-9. LMI was also supported for all tested veteran subgroups. As such, PHQ-9 sum scores can be compared across extended pharmacotherapy treatment durations. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

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在接受药物治疗的重度抑郁障碍患者中,患者健康问卷-9 的纵向不变性:临床试验数据的二次分析。
比较不同时间段的自我报告症状得分需要纵向测量不变性(LMI),这是一种心理测量特性,意味着测量结果在所有时间点上的功能都是相同的。尽管患者健康问卷-9 抑郁症模块(PHQ-9)作为抑郁症状严重程度的测量指标在研究和医疗保健领域都占有重要地位,但其纵向测量不变性仍有待进一步证实,尤其是在抗抑郁药物治疗过程中。因此,本研究旨在评估重度抑郁障碍药物治疗过程中 PHQ-9 的 LMI。这是对随机对照试验期间收集的数据进行的二次分析。共有 1,944 名退伍军人开始接受抗抑郁药单一疗法,并在 24 周的治疗期间完成了六次 PHQ-9。LMI 采用一系列包含所有六个时间点的四个确证因素分析模型进行评估,各模型的估计参数限制越来越多,以测试不同方面的不变性。齐次方差检验的均方根近似误差值低于 0.06 表示存在 LMI。此外,还针对不同的性别、年龄和种族分组进行了探索性 LMI 分析。卡方差检验的均方根近似误差显示,在不变量测试期间,模型拟合的变化极小(所有步骤均小于 0.06),支持 PHQ-9 的完全 LMI。所有接受测试的退伍军人亚群也都支持 LMI。因此,PHQ-9总分可在延长的药物治疗持续时间内进行比较。(PsycInfo Database Record (c) 2024 APA,版权所有)。
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来源期刊
Psychological Assessment
Psychological Assessment PSYCHOLOGY, CLINICAL-
CiteScore
5.70
自引率
5.60%
发文量
167
期刊介绍: Psychological Assessment is concerned mainly with empirical research on measurement and evaluation relevant to the broad field of clinical psychology. Submissions are welcome in the areas of assessment processes and methods. Included are - clinical judgment and the application of decision-making models - paradigms derived from basic psychological research in cognition, personality–social psychology, and biological psychology - development, validation, and application of assessment instruments, observational methods, and interviews
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