The effect of different concentrations of yttrium gadolinium orthovanadate nanoparticles on breast cancer cell line MCF-7

O. A. Nakonechna, V. Y. Prokopyuk, О. S. Sydorenko, V. S. Hoidina, D. O. Yankovska
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Abstract

The article analyzes the effect of different concentrations of GdYVO4 :Eu3+ nanoparticles solution, which were pre-activated by ultraviolet light and not activated, on metabolic activity of the MCF-7 cancer cell culture. It was found that the degree of changes in the state of breast cancer cells depended on the concentration of nanoparticles, namely, the toxic effect was observed under conditions of exposure to high concentrations.
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不同浓度的正钒酸钇钆纳米粒子对乳腺癌细胞株 MCF-7 的影响
文章分析了不同浓度的 GdYVO4 :Eu3+ 纳米粒子溶液(经紫外线预活化和未被活化)对 MCF-7 癌细胞培养物代谢活性的影响。研究发现,乳腺癌细胞状态的变化程度取决于纳米粒子的浓度,即在接触高浓度纳米粒子的条件下观察到毒性效应。
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