CLINICAL PROFILE AND SPUTUM POSITIVITY RATE OF SUSPECTED PULMONARY TUBERCULOSIS PATIENTS PRESENTING TO A TERTIARY CARE HOSPITAL IN SOUTHERN RAJASTHAN

Asian Journal of Pharmaceutical and Clinical Research Pub Date : 2024-05-07 DOI:10.22159/ajpcr.2024.v17i5.51056

Amit Satish Gupta, Hirenkumar Punjabhai Hadiya, Amar Gahlot

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Abstract

Objective: The purpose of the study is to understand the sputum acid-fast bacilli (AFB) positivity rate among suspected pulmonary tuberculosis (TB) patients presenting to tertiary care hospital in Southern Rajasthan with symptoms of chronic cough for more than 2 weeks. Methods: It is a retrospective observational study. Data from June 2021 to March 2024 were collected from registers maintained by the respiratory medicine department and analyzed. Results: Out of 1720 sputum samples of suspected pulmonary TB patients that were sent for microscopy 344 were AFB positive (20%) and 292 patients (16.97%) were GeneXpert positive. A total of 21 patients (1.22%) were found to have multidrug-resistant (MDR)-TB based on sputum GeneXpert testing. Most of the patients in our study were males and the sputum positivity rate was higher among diabetic and HIV-positive patients. Conclusion: In this study out of 1720 sputum samples analyzed for suspected pulmonary TB patients, 344 were sputum AFB positive (20%) and 21 were MDR-TB (1.22%).

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在拉贾斯坦邦南部一家三级医院就诊的肺结核疑似患者的临床概况和痰液阳性率

研究目的本研究旨在了解在拉贾斯坦邦南部的三级医院就诊的肺结核（TB）疑似患者中，因慢性咳嗽症状超过 2 周而出现痰液酸性粘杆菌（AFB）阳性的比例：这是一项回顾性观察研究。方法：这是一项回顾性观察研究，研究人员从呼吸内科的登记簿中收集了 2021 年 6 月至 2024 年 3 月期间的数据，并对这些数据进行了分析：在送去显微镜检查的 1720 份肺结核疑似患者痰液样本中，344 份（20%）为 AFB 阳性，292 份（16.97%）为 GeneXpert 阳性。根据痰基因Xpert检测结果，共有21名患者（1.22%）被发现患有耐多药（MDR）肺结核。本研究中的大多数患者为男性，糖尿病患者和 HIV 阳性患者的痰液阳性率较高：本研究分析了 1720 例疑似肺结核患者的痰液样本，其中 344 例痰液 AFB 阳性（20%），21 例 MDR-TB 阳性（1.22%）。

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Asian Journal of Pharmaceutical and Clinical Research

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