{"title":"A method of fluorescence molecular tomographic reconstruction via the second-order sensitivity matrix","authors":"W. Zou","doi":"10.1051/jeos/2024025","DOIUrl":null,"url":null,"abstract":"Fluorescence molecular tomographic (FMT) reconstruction is commonly solved based on the Jacobian matrix, which is a first-order sensitivity matrix. Basically, using the second-order derivatives for iterative reconstruction can help improve the performance of convergence. In this paper, a reconstruction method of FMT based on the reduction of the second-order sensitivity matrix is proposed. In addition, the strategy of detectors rotation is combined into the inverse reconstruction to further improve the reconstruction quality. The reconstructed results demonstrate that the proposed method accelerates the reconstruction with high precision of inverse solutions.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":"101 4","pages":""},"PeriodicalIF":17.7000,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"4","ListUrlMain":"https://doi.org/10.1051/jeos/2024025","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Fluorescence molecular tomographic (FMT) reconstruction is commonly solved based on the Jacobian matrix, which is a first-order sensitivity matrix. Basically, using the second-order derivatives for iterative reconstruction can help improve the performance of convergence. In this paper, a reconstruction method of FMT based on the reduction of the second-order sensitivity matrix is proposed. In addition, the strategy of detectors rotation is combined into the inverse reconstruction to further improve the reconstruction quality. The reconstructed results demonstrate that the proposed method accelerates the reconstruction with high precision of inverse solutions.
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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