An Unusual Case Report of Cotard’s Syndrome with Depressive Delusions

Amlan Das, Soumitra Ghosh, Kavery Bora
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Abstract

Cotard’s Syndrome, also known as nihilistic delusion or Cotard’s delusion, is an exceptionally rare psychiatric condition characterized by delusional beliefs ranging from a sense of being dead to the conviction of bodily decay or nonexistence. This case report of a male patient, aged 21 years, with Cotard’s Syndrome highlights the difficulties in diagnosis, the course of therapy, and the clinical ramifications of this illness. The patient exhibited symptoms of severe depression along with nihilistic delusions, expressing the belief that he was deceased and experiencing bodily decay. Nihilistic delusions and depressed symptoms compatible with Cotard’s syndrome in the setting of major depressive disorder were found during the patient’s mental state evaluation, despite the absence of a serious physical disease or drug addiction. Treatment consisted of antidepressant and antipsychotic medication, along with individual psychotherapy sessions focusing on cognitive restructuring. Over time, the patient demonstrated gradual improvement in delusional beliefs and depressive symptoms, highlighting the importance of comprehensive psychiatric evaluation and individualized treatment planning.
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科塔德综合征伴有抑郁性妄想的罕见病例报告
科塔德综合征(Cotard's Syndrome)又称虚无主义妄想症或科塔德妄想症,是一种异常罕见的精神疾病,以妄想信念为特征,范围从死亡感到确信身体腐烂或不存在。本病例报告的患者是一名 21 岁的男性科塔德综合征患者,该病例凸显了这种疾病在诊断、治疗过程和临床影响方面的困难。患者表现出严重的抑郁症状,并伴有虚无主义妄想,认为自己已经死亡,身体正在腐烂。尽管患者没有严重的躯体疾病或毒瘾,但在对其进行精神状态评估时,发现其虚无主义妄想和抑郁症状与重度抑郁症的科塔德综合征相符。治疗包括抗抑郁和抗精神病药物治疗,以及以认知重组为重点的个体心理治疗。随着时间的推移,患者的妄想信念和抑郁症状逐渐好转,这凸显了全面精神评估和个体化治疗计划的重要性。
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