Eco-Synthesis of Gold Nanoparticles Using Vigna unguiculata Seed Extract: A Leap in the Direction of Antiglycation Remedies

IF 0.9 4区 材料科学 Science of Advanced Materials Pub Date : 2024-05-01 DOI:10.1166/sam.2024.4671
A. Alsukaibi, Salman Khan, Mohd Wajid Ali Khan, Zeeshan Rafi, Ahmed Al-Otaibi, A. Alshamari, Kirtanjot Kaur, L. Mechi, F. Alimi, Eida M. Alshammari, Ramendra Pati Pandey, Ahmad Umar, Saheem Ahmad
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Abstract

Nanotechnology, an interdisciplinary field that merges physics, chemistry, and biology, has emerged as a catalyst for innovation, offering far-reaching implications across various scientific disciplines. Gold nanoparticles (GNPs), with their unique physicochemical properties and biocompatibility, have become a focal point in this technological revolution. This research delves into the eco-friendly synthesis of gold nanoparticles using Vigna unguiculata seed extract, a botanical resource known for its rich phytochemical composition. The study investigates the antiglycation activities of these nanoparticles, drawing insights from existing literature. The synthesis process involves the reduction of gold ions by the bioactive compounds present in the Vigna unguiculata seed extract (VuS), leading to the formation of Vigna unguiculata derived GNPs (V-GNPs). Comprehensive characterization techniques, including UV-Vis spectroscopy and transmission electron microscopy, were employed to confirm the stability, size, and shape of the synthesized nanoparticles. The research aligns with recent studies suggesting the potential of gold nanoparticles in mitigating glycation-related disorders. Glycation is a biochemical process implicated in various health complications, particularly diabetes. The antiglycation properties of V-GNPs, as revealed in this study, present an intriguing avenue for managing diabetes and associated complications. The unique composition of V-GNPs, coupled with their promising antiglycation properties, underscores their potential as effective therapeutic agents in the fight against diabetes and other glycation-related disorders. This research not only contributes to the existing body of knowledge but also opens up new possibilities for the application of V-GNPs in the realm of nanomedicine.
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利用木葡萄籽提取物生态合成金纳米粒子:抗糖化疗法的一次飞跃
纳米技术是一个融合了物理学、化学和生物学的跨学科领域,已成为创新的催化剂,对各个科学学科产生了深远的影响。金纳米粒子(GNPs)具有独特的物理化学特性和生物相容性,已成为这场技术革命的焦点。本研究利用以植物化学成分丰富而著称的植物资源 Vigna unguiculata 种子提取物,深入研究了金纳米粒子的生态友好型合成。研究从现有文献中汲取灵感,探讨了这些纳米粒子的抗糖化活性。合成过程包括金葡萄籽提取物(VuS)中的生物活性化合物还原金离子,从而形成金葡萄籽衍生 GNPs(V-GNPs)。研究采用了包括紫外可见光谱和透射电子显微镜在内的综合表征技术,以确认合成纳米粒子的稳定性、尺寸和形状。这项研究与最近的研究一致,表明金纳米粒子在缓解糖化相关疾病方面具有潜力。糖化是一种生化过程,与各种健康并发症,尤其是糖尿病有关。本研究揭示的 V-GNPs 的抗糖化特性为控制糖尿病及相关并发症提供了一条令人感兴趣的途径。V-GNPs 的独特成分及其良好的抗糖化特性,凸显了其作为有效治疗剂,对抗糖尿病和其他糖化相关疾病的潜力。这项研究不仅为现有知识体系做出了贡献,还为 V-GNPs 在纳米医学领域的应用开辟了新的可能性。
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来源期刊
Science of Advanced Materials
Science of Advanced Materials NANOSCIENCE & NANOTECHNOLOGY-MATERIALS SCIENCE, MULTIDISCIPLINARY
自引率
11.10%
发文量
98
审稿时长
4.4 months
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