CardioXplorer: An Open-Source Modular Teleoperative Robotic Catheter Ablation System

IF 4.7 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-05-19 DOI:10.3390/robotics13050080
Zhouyang Xu, A. Zeidan, Yetao He, Lisa W M Leung, Calum Byrne, Sachin Sabu, Yuanwei Wu, Zhiyue Chen, Steven E. Williams, Lukas Lindenroth, Jonathan Behar, Christopher Aldo Rinaldi, John Whitaker, A. Arujuna, R. Housden, K. Rhode
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Abstract

Atrial fibrillation, the most prevalent cardiac arrhythmia, is treated by catheter ablation to isolate electrical triggers. Clinical trials on robotic catheter systems hold promise for improving the safety and efficacy of the procedure. However, expense and proprietary designs hinder accessibility to such systems. This paper details an open-source, modular, three-degree-of-freedom robotic platform for teleoperating commercial ablation catheters through joystick navigation. We also demonstrate a catheter-agnostic handle interface permitting customization with commercial catheters. Collaborating clinicians performed benchtop targeting trials, comparing manual and robotic catheter navigation performance. The robot reduced task duration by 1.59 s across participants and five trials. Validation through mean motion jerk analysis revealed 35.2% smoother robotic navigation for experts (≥10 years experience) compared to the intermediate group. Yet, both groups achieved smoother robot motion relative to the manual approach, with the experts and intermediates exhibiting 42.2% and 13.6% improvements, respectively. These results highlight the potential of this system for enhancing catheter-based procedures. The source code and designs of CardioXplorer have been made publicly available to lower boundaries and drive innovations that enhance procedure efficacy beyond human capabilities.
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CardioXplorer:开源模块化远程手术机器人导管消融系统
心房颤动是最常见的心律失常,其治疗方法是通过导管消融术隔离电触发器。机器人导管系统的临床试验为提高手术的安全性和有效性带来了希望。然而,费用和专有设计阻碍了此类系统的普及。本文详细介绍了一种开源、模块化、三自由度机器人平台,可通过操纵杆导航远程操作商用消融导管。我们还展示了一个导管识别手柄界面,允许定制商用导管。合作临床医生进行了台式瞄准试验,比较了手动和机器人导管导航的性能。在五次试验中,机器人将任务持续时间缩短了 1.59 秒。通过平均运动抽搐分析进行验证后发现,与中级组相比,专家组(经验≥10 年)的机器人导航平稳性提高了 35.2%。然而,与手动方法相比,两组人都实现了更平滑的机器人运动,专家组和中级组分别提高了 42.2% 和 13.6%。这些结果凸显了该系统在改进导管手术方面的潜力。CardioXplorer的源代码和设计已经公开,以降低界限并推动创新,从而提高手术效率,超越人类的能力。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊介绍: ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
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