Systematic Review and Meta-analysis of the Association Between Malnutrition and Risk of Depression in the Elderly.

IF 1.3 Q3 PSYCHIATRY Alpha psychiatry Pub Date : 2024-03-01 DOI:10.5152/alphapsychiatry.2024.231336

Weiwei Hu, Huiping Mao, Shasha Guan, Jia Jin, Dan Xu

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Abstract

Objective: To explore the association between malnutrition and risk of depression in the elderly.

Methods: Relevant studies were searched in PubMed, Web of Science, the Cochrane Library, Scopus, and Embase from the establishment of the database to August 17, 2023. Two researchers independently screened the literature, extracted data, and evaluated the risk of bias in the included studies. Stata16.0 software was used for meta-analysis.

Results: A total of 8 observational studies were identified with 11 112 participants, of which 2771 elderly patients had depression. The meta-pooled results showed a significant correlation between nutritional status and depression risk (odds ratio (OR) = 2.03, 95% CI = (1.47, 2.81), P < 0.001). Subgroup analysis found that the malnutrition scores of different study types and the diagnostic methods of depression and malnutrition were correlated with the risk of depression.

Conclusion: Malnutrition was associated with depression risk in the elderly. Further large-scale multicenter studies should be conducted to test and verify the results.

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老年人营养不良与抑郁风险之间关系的系统回顾和元分析》。

目的：探讨营养不良与老年人抑郁风险之间的关系：探讨营养不良与老年人抑郁风险之间的关系：在 PubMed、Web of Science、Cochrane Library、Scopus 和 Embase 中检索了自数据库建立至 2023 年 8 月 17 日期间的相关研究。两名研究人员独立筛选文献、提取数据并评估纳入研究的偏倚风险。使用Stata16.0软件进行荟萃分析：共发现 8 项观察性研究，11 112 名参与者，其中 2771 名老年抑郁症患者。汇总结果显示，营养状况与抑郁风险之间存在显著相关性（几率比（OR）= 2.03，95% CI = (1.47，2.81)，P < 0.001）。亚组分析发现，不同研究类型的营养不良评分以及抑郁和营养不良的诊断方法与抑郁风险相关：结论：营养不良与老年人抑郁风险有关。结论：营养不良与老年人抑郁风险有关，应进一步开展大规模多中心研究，以检验和验证研究结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Alpha psychiatry

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