Risk of central line-associated bloodstream infections during COVID-19 pandemic in intensive care patients in a tertiary care centre in Saudi Arabia.

IF 2.5 4区 医学 Q3 INFECTIOUS DISEASES Epidemiology and Infection Pub Date : 2024-06-03 DOI:10.1017/S0950268824000736
Majid M Alshamrani, Aiman El-Saed, Omar Aldayhani, Abdulaziz Alhassan, Abdullah Alhamoudi, Mohammed Alsultan, Mohammed Alrasheed, Fatmah Othman
{"title":"Risk of central line-associated bloodstream infections during COVID-19 pandemic in intensive care patients in a tertiary care centre in Saudi Arabia.","authors":"Majid M Alshamrani, Aiman El-Saed, Omar Aldayhani, Abdulaziz Alhassan, Abdullah Alhamoudi, Mohammed Alsultan, Mohammed Alrasheed, Fatmah Othman","doi":"10.1017/S0950268824000736","DOIUrl":null,"url":null,"abstract":"<p><p>This retrospective study compared central line-associated bloodstream infection (CLABSI) rates per 1 000 central line days, and overall mortality before and during the COVID-19 pandemic in adult, paediatric, and neonatal ICU patients at King Abdul-Aziz Medical City-Riyadh who had a central line and were diagnosed with CLABSI according to the National Healthcare Safety Network standard definition. The study spanned between January 2018 and December 2019 (pre-pandemic), and January 2020 and December 2021 (pandemic). SARS-CoV-2 was confirmed by positive RT-PCR testing. The study included 156 CLABSI events and 46 406 central line days; 52 and 22 447 (respectively) in pre-pandemic, and 104 and 23 959 (respectively) during the pandemic. CLABSI rates increased by 2.02 per 1 000 central line days during the pandemic period (from 2.32 to 4.34, <i>p</i> < 0.001). Likewise, overall mortality rates increased by 0.86 per 1 000 patient days (from 0.93 to 1.79, <i>p</i> = 0.003). Both CLABSI rates (6.18 vs. 3.7, <i>p</i> = 0.006) and overall mortality (2.72 vs. 1.47, <i>p</i> = 0.014) were higher among COVID-19 patients compared to non-COVID-19 patients. The pandemic was associated with a substantial increase in CLABSI-associated morbidity and mortality.</p>","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"e95"},"PeriodicalIF":2.5000,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Epidemiology and Infection","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1017/S0950268824000736","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0

Abstract

This retrospective study compared central line-associated bloodstream infection (CLABSI) rates per 1 000 central line days, and overall mortality before and during the COVID-19 pandemic in adult, paediatric, and neonatal ICU patients at King Abdul-Aziz Medical City-Riyadh who had a central line and were diagnosed with CLABSI according to the National Healthcare Safety Network standard definition. The study spanned between January 2018 and December 2019 (pre-pandemic), and January 2020 and December 2021 (pandemic). SARS-CoV-2 was confirmed by positive RT-PCR testing. The study included 156 CLABSI events and 46 406 central line days; 52 and 22 447 (respectively) in pre-pandemic, and 104 and 23 959 (respectively) during the pandemic. CLABSI rates increased by 2.02 per 1 000 central line days during the pandemic period (from 2.32 to 4.34, p < 0.001). Likewise, overall mortality rates increased by 0.86 per 1 000 patient days (from 0.93 to 1.79, p = 0.003). Both CLABSI rates (6.18 vs. 3.7, p = 0.006) and overall mortality (2.72 vs. 1.47, p = 0.014) were higher among COVID-19 patients compared to non-COVID-19 patients. The pandemic was associated with a substantial increase in CLABSI-associated morbidity and mortality.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
沙特阿拉伯一家三级医疗中心的重症监护患者在 COVID-19 大流行期间发生中心静脉相关血流感染 (CLABSI) 的风险。
这项回顾性研究比较了利雅得阿卜杜勒-阿齐兹国王医疗城的成人、儿科和新生儿 ICU 患者在 COVID-19 大流行之前和期间每 1000 个中心管路日的中心管路相关血流感染(CLABSI)率和总死亡率,根据国家医疗安全网的标准定义,这些患者均使用了中心管路并被诊断为 CLABSI。研究时间跨度为 2018 年 1 月至 2019 年 12 月(大流行前)和 2020 年 1 月至 2021 年 12 月(大流行)。SARS-CoV-2通过阳性RT-PCR检测得到确认。研究包括 156 起 CLABSI 事件和 46 406 个中心管路日;大流行前分别为 52 起和 22 447 个,大流行期间分别为 104 起和 23 959 个。大流行期间,每千个中心管路日的 CLABSI 感染率增加了 2.02(从 2.32 增加到 4.34,P = 0.003)。与非 COVID-19 患者相比,COVID-19 患者的 CLABSI 感染率(6.18 vs. 3.7,p = 0.006)和总死亡率(2.72 vs. 1.47,p = 0.014)均较高。大流行导致 CLABSI 相关发病率和死亡率大幅上升。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Epidemiology and Infection
Epidemiology and Infection 医学-传染病学
CiteScore
4.10
自引率
2.40%
发文量
366
审稿时长
3-6 weeks
期刊介绍: Epidemiology & Infection publishes original reports and reviews on all aspects of infection in humans and animals. Particular emphasis is given to the epidemiology, prevention and control of infectious diseases. The scope covers the zoonoses, outbreaks, food hygiene, vaccine studies, statistics and the clinical, social and public-health aspects of infectious disease, as well as some tropical infections. It has become the key international periodical in which to find the latest reports on recently discovered infections and new technology. For those concerned with policy and planning for the control of infections, the papers on mathematical modelling of epidemics caused by historical, current and emergent infections are of particular value.
期刊最新文献
Community-associated methicillin-resistant Staphylococcus aureus in the Kimberley region of Western Australia, epidemiology and burden on hospitals. Reducing antimicrobial use in livestock alone may be not sufficient to reduce antimicrobial resistance among human Campylobacter infections: an ecological study in the Netherlands. A self-driven ESN-DSS approach for effective COVID-19 time series prediction and modelling. Identifying risk factors for clinical Lassa fever in Sierra Leone, 2019-2021. Association between age of paediatric index cases and household SARS-CoV-2 transmission.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1