Multimodal Data Hybrid Fusion and Natural Language Processing for Clinical Prediction Models.

Jiancheng Ye, Jiarui Hai, Jiacheng Song, Zidan Wang
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Abstract

This study aims to propose a novel approach for enhancing clinical prediction models by combining structured and unstructured data with multimodal data fusion. We presented a comprehensive framework that integrated multimodal data sources, including textual clinical notes, structured electronic health records (EHRs), and relevant clinical data from National Electronic Injury Surveillance System (NEISS) datasets. We proposed a novel hybrid fusion method, which incorporated state-of-the-art pre-trained language model, to integrate unstructured clinical text with structured EHR data and other multimodal sources, thereby capturing a more comprehensive representation of patient information. The experimental results demonstrated that the hybrid fusion approach significantly improved the performance of clinical prediction models compared to traditional fusion frameworks and unimodal models that rely solely on structured data or text information alone. The proposed hybrid fusion system with RoBERTa language encoder achieved the best prediction of the Top 1 injury with an accuracy of 75.00% and Top 3 injuries with an accuracy of 93.54%. Our study highlights the potential of integrating natural language processing (NLP) techniques with multimodal data fusion for enhancing clinical prediction models' performances. By leveraging the rich information present in clinical text and combining it with structured EHR data, the proposed approach can improve the accuracy and robustness of predictive models. The approach has the potential to advance clinical decision support systems, enable personalized medicine, and facilitate evidence-based health care practices. Future research can further explore the application of this hybrid fusion approach in real-world clinical settings and investigate its impact on improving patient outcomes.

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用于临床预测模型的多模态数据混合融合与自然语言处理。
本研究旨在提出一种新方法,通过多模态数据融合将结构化和非结构化数据结合起来,从而增强临床预测模型。我们提出了一个综合框架,该框架整合了多模态数据源,包括文本临床笔记、结构化电子健康记录(EHR)以及来自国家电子伤害监测系统(NEISS)数据集的相关临床数据。我们提出了一种新颖的混合融合方法,该方法结合了最先进的预训练语言模型,将非结构化临床文本与结构化电子病历数据和其他多模态数据源整合在一起,从而更全面地呈现患者信息。实验结果表明,与传统的融合框架和仅依赖结构化数据或文本信息的单模态模型相比,混合融合方法显著提高了临床预测模型的性能。使用 RoBERTa 语言编码器的混合融合系统对前 1 名损伤的预测准确率达到 75.00%,对前 3 名损伤的预测准确率达到 93.54%。我们的研究强调了自然语言处理(NLP)技术与多模态数据融合在提高临床预测模型性能方面的潜力。通过利用临床文本中的丰富信息并将其与结构化电子病历数据相结合,所提出的方法可以提高预测模型的准确性和稳健性。该方法有望推动临床决策支持系统的发展,实现个性化医疗,促进循证医疗实践。未来的研究可以进一步探索这种混合融合方法在实际临床环境中的应用,并研究其对改善患者预后的影响。
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