Hazard identification of endocrine-disrupting carcinogens (EDCs) in relation to cancers in humans

IF 5.4 3区材料科学 Q2 CHEMISTRY, PHYSICAL ACS Applied Energy Materials Pub Date : 2024-05-31 DOI:10.1016/j.etap.2024.104480

Neha Sharma , Vinay Kumar , Vimal S. , Mridul Umesh , Preeti Sharma , Basheer Thazeem , Komalpreet Kaur , Jithin Thomas , Ritu Pasrija , Divya Utreja

{"title":"Hazard identification of endocrine-disrupting carcinogens (EDCs) in relation to cancers in humans","authors":"Neha Sharma , Vinay Kumar , Vimal S. , Mridul Umesh , Preeti Sharma , Basheer Thazeem , Komalpreet Kaur , Jithin Thomas , Ritu Pasrija , Divya Utreja","doi":"10.1016/j.etap.2024.104480","DOIUrl":null,"url":null,"abstract":"<div><p>Endocrine disrupting chemicals or carcinogens have been known for decades for their endocrine signal disruption. Endocrine disrupting chemicals are a serious concern and they have been included in the top priority toxicants and persistent organic pollutants. Therefore, researchers have been working for a long time to understand their mechanisms of interaction in different human organs. Several reports are available about the carcinogen potential of these chemicals. The presented review is an endeavor to understand the hazard identification associated with endocrine disrupting carcinogens in relation to the human body. The paper discusses the major endocrine disrupting carcinogens and their potency for carcinogenesis. It discusses human exposure, route of entry, carcinogenicity and mechanisms. In addition, the paper discusses the research gaps and bottlenecks associated with the research. Moreover, it discusses the limitations associated with the analytical techniques for detection of endocrine disrupting carcinogens.</p></div>","PeriodicalId":4,"journal":{"name":"ACS Applied Energy Materials","volume":null,"pages":null},"PeriodicalIF":5.4000,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Energy Materials","FirstCategoryId":"93","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1382668924001200","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}

引用次数: 0

Abstract

Endocrine disrupting chemicals or carcinogens have been known for decades for their endocrine signal disruption. Endocrine disrupting chemicals are a serious concern and they have been included in the top priority toxicants and persistent organic pollutants. Therefore, researchers have been working for a long time to understand their mechanisms of interaction in different human organs. Several reports are available about the carcinogen potential of these chemicals. The presented review is an endeavor to understand the hazard identification associated with endocrine disrupting carcinogens in relation to the human body. The paper discusses the major endocrine disrupting carcinogens and their potency for carcinogenesis. It discusses human exposure, route of entry, carcinogenicity and mechanisms. In addition, the paper discusses the research gaps and bottlenecks associated with the research. Moreover, it discusses the limitations associated with the analytical techniques for detection of endocrine disrupting carcinogens.

Abstract Image

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

干扰内分泌的致癌物质（EDCs）与人类癌症的危害识别。

内分泌干扰化学品或致癌物质因其干扰内分泌信号而闻名于世已有几十年。内分泌干扰化学物是一个令人严重关切的问题，它们已被列入首要有毒物质和持久性有机污染物。因此，研究人员长期以来一直致力于了解它们在不同人体器官中的相互作用机制。关于这些化学物质的致癌潜力，已有多份报告。本综述旨在了解干扰内分泌的致癌物质对人体的危害识别。本文讨论了干扰内分泌的主要致癌物质及其致癌作用。论文讨论了人体接触、进入途径、致癌性和机制。此外，论文还讨论了与研究相关的研究空白和瓶颈。此外，论文还讨论了检测干扰内分泌的致癌物质的分析技术的局限性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

ACS Applied Energy Materials Materials Science-Materials Chemistry

CiteScore

10.30

自引率

6.20%

发文量

1368

期刊介绍： ACS Applied Energy Materials is an interdisciplinary journal publishing original research covering all aspects of materials, engineering, chemistry, physics and biology relevant to energy conversion and storage. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important energy applications.