Outcome of Late Neurolysis on Median and Cubital Nerve Neuropathies: Insights from A Preliminary Prospective Study

Mauro Maniglio
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Abstract

Background: Nerve decompression represents the treatment in which a nerve is freed from compressing surrounding. It should be ideally performed before neural changes become irreversible following long-term entrapment. No consensus exists on a critical time limit that would make surgery worthwhile. This study aims to investigate whether or not late (12 months after occurrence of symptoms) nerve decompression has still a positive impact on patient’s symptoms. Methods: This prospective study included 16 patients with carpal tunnel syndrome (8) or ulnar nerve entrapment (8) lasting for more than 12 months. Symptoms, motor and sensory functions were assessed before surgery, at 3,6 and 12 months after nerve decompression. Results: After median nerve decompression, pain decreased by 85%. Paresthesia resolved in all patients and nighttime symptoms decreased in 83% cases. Following ulnar decompression, pain decreased by 75 % and numbness resolved in 87% patients. Subjective sensibility increased by 25%, attested with Ten test. Measure of 2-PD decreased by 60% when compared to preoperative values. Grip strength improved to 40%. Conclusion: Despite uncomplete recovery one year after surgery, we believe that nerve decompressions should be indented even in case of chronic symptoms.
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正中神经和肘神经病晚期神经切除术的效果:一项初步前瞻性研究的启示
背景:神经减压术是一种将神经从压迫周围组织中解脱出来的治疗方法。理想情况下,应在神经长期受压后发生不可逆转的变化之前进行手术。目前还没有就值得进行手术的关键时限达成共识。本研究旨在探讨晚期(症状出现 12 个月后)神经减压术对患者症状是否仍有积极影响:这项前瞻性研究纳入了 16 名持续时间超过 12 个月的腕管综合征(8 名)或尺神经卡压(8 名)患者。手术前、神经减压术后 3、6 和 12 个月对患者的症状、运动和感觉功能进行了评估:结果:正中神经减压术后,疼痛减轻了 85%。结果:正中神经减压术后,疼痛减轻了 85%,所有患者的麻痹症状均得到缓解,83% 的患者夜间症状减轻。尺神经减压术后,75%的患者疼痛减轻,87%的患者麻木症状消失。主观感受性增加了 25%,十项测试证明了这一点。与术前相比,2-PD值下降了60%。握力提高了 40%:尽管术后一年仍未完全康复,但我们认为,即使出现慢性症状,也应进行神经减压术。
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