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Impact of Women's Sexual Health on Prostate Cancer Risk in Men 女性性健康对男性前列腺癌风险的影响
Pub Date : 2024-08-13 DOI: 10.46889/jsrp.2024.5207
Mboudou Michel Salomon
Introduction: Prostate cancer is a significant health issue for men. This study investigates whether women’s sexual health and relationship satisfaction influence prostate cancer risk in their male partners.Methods: We conducted a prospective cohort study involving 1,000 heterosexual couples where the male partner was over 40 years old. Couples in stable relationships with no prior history of prostate cancer were included. Baseline data included demographic information, medical history, lifestyle factors, the Female Sexual Function Index (FSFI) and the Dyadic Adjustment Scale (DAS) to assess women’s sexual health and relationship satisfaction. Sexual activity frequency was also recorded. Participants were followed annually for 10 years to track prostate cancer incidence in men. We used Pearson correlation and multivariate Cox proportional hazards regression for statistical analysis.Results: We found a significant negative correlation between FSFI scores and prostate cancer incidence (r = -0.42, p < 0.05). Higher DAS scores and more frequent sexual activity were also associated with a reduced risk of prostate cancer (r = -0.35 and r = -0.38, respectively, both p < 0.05). These results suggest that better sexual function and relationship satisfaction in women are linked to a lower risk of prostate cancer in their male partners.Conclusion: Women’s positive sexual health and relationship satisfaction may reduce prostate cancer risk in men. These findings underscore the importance of considering partner dynamics in prostate cancer prevention strategies and encourage further research into underlying mechanisms.
导言前列腺癌是男性的重大健康问题。本研究调查了女性的性健康和关系满意度是否会影响其男性伴侣患前列腺癌的风险:我们进行了一项前瞻性队列研究,涉及 1000 对男性伴侣年龄超过 40 岁的异性伴侣。研究对象包括关系稳定、无前列腺癌病史的夫妇。基线数据包括人口统计学信息、病史、生活方式因素、女性性功能指数(FSFI)以及用于评估女性性健康和夫妻关系满意度的 "夫妻适应量表"(DAS)。此外,还记录了性活动频率。每年对参与者进行为期 10 年的跟踪调查,以追踪男性前列腺癌的发病率。我们使用皮尔逊相关性和多变量考克斯比例危险回归进行统计分析:我们发现,FSFI 评分与前列腺癌发病率之间存在明显的负相关(r = -0.42,p < 0.05)。更高的 DAS 评分和更频繁的性活动也与前列腺癌风险的降低有关(r = -0.35 和 r = -0.38,均 p <0.05)。这些结果表明,女性较好的性功能和关系满意度与其男性伴侣患前列腺癌的风险较低有关:结论:女性积极的性健康和关系满意度可降低男性患前列腺癌的风险。这些发现强调了在前列腺癌预防策略中考虑伴侣动态的重要性,并鼓励进一步研究其潜在机制。
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引用次数: 0
Impact of Women's Sexual Health on Prostate Cancer Risk in Men 女性性健康对男性前列腺癌风险的影响
Pub Date : 2024-08-13 DOI: 10.46889/jsrp.2024.5207
Mboudou Michel Salomon
Introduction: Prostate cancer is a significant health issue for men. This study investigates whether women’s sexual health and relationship satisfaction influence prostate cancer risk in their male partners.Methods: We conducted a prospective cohort study involving 1,000 heterosexual couples where the male partner was over 40 years old. Couples in stable relationships with no prior history of prostate cancer were included. Baseline data included demographic information, medical history, lifestyle factors, the Female Sexual Function Index (FSFI) and the Dyadic Adjustment Scale (DAS) to assess women’s sexual health and relationship satisfaction. Sexual activity frequency was also recorded. Participants were followed annually for 10 years to track prostate cancer incidence in men. We used Pearson correlation and multivariate Cox proportional hazards regression for statistical analysis.Results: We found a significant negative correlation between FSFI scores and prostate cancer incidence (r = -0.42, p < 0.05). Higher DAS scores and more frequent sexual activity were also associated with a reduced risk of prostate cancer (r = -0.35 and r = -0.38, respectively, both p < 0.05). These results suggest that better sexual function and relationship satisfaction in women are linked to a lower risk of prostate cancer in their male partners.Conclusion: Women’s positive sexual health and relationship satisfaction may reduce prostate cancer risk in men. These findings underscore the importance of considering partner dynamics in prostate cancer prevention strategies and encourage further research into underlying mechanisms.
导言前列腺癌是男性的重大健康问题。本研究调查了女性的性健康和关系满意度是否会影响其男性伴侣患前列腺癌的风险:我们进行了一项前瞻性队列研究,涉及 1000 对男性伴侣年龄超过 40 岁的异性伴侣。研究对象包括关系稳定、无前列腺癌病史的夫妇。基线数据包括人口统计学信息、病史、生活方式因素、女性性功能指数(FSFI)以及用于评估女性性健康和夫妻关系满意度的 "夫妻适应量表"(DAS)。此外,还记录了性活动频率。每年对参与者进行为期 10 年的跟踪调查,以追踪男性前列腺癌的发病率。我们使用皮尔逊相关性和多变量考克斯比例危害回归进行统计分析:我们发现,FSFI 评分与前列腺癌发病率之间存在明显的负相关(r = -0.42,p < 0.05)。更高的 DAS 评分和更频繁的性活动也与前列腺癌风险的降低有关(r = -0.35 和 r = -0.38,均 p <0.05)。这些结果表明,女性较好的性功能和关系满意度与其男性伴侣患前列腺癌的风险较低有关:结论:女性积极的性健康和关系满意度可降低男性患前列腺癌的风险。这些发现强调了在前列腺癌预防策略中考虑伴侣动态的重要性,并鼓励进一步研究其潜在机制。
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引用次数: 0
Avoiding Aortic Arch Debranching with a Custom-Made Solution a Tailored Approach to Aortic Disease 用定制解决方案避免主动脉弓分支切除量身定制的主动脉疾病治疗方法
Pub Date : 2024-07-02 DOI: 10.46889/jsrp.2024/5206
Daniele Linardi
Penetrating Atherosclerotic Ulcer (PAU) is one of the acute aortic syndromes representing a medical and surgical emergency that could lead to rapid evolution and significant complications. Depending on the aortic section involved in the PAU, the treatment with endovascular prosthesis could be challenging and often requires personalized prosthesis to face anatomical peculiarities. The aortic arch could be one of the most complex locations due to the origin of supra-aortic branches and the need for previous or subsequent carotid-subclavian bypass grafting. The use of scalloped and fenestrated prostheses makes it possible to manage aortic pathology without further vascular surgery.
穿透性动脉粥样硬化溃疡(PAU)是急性主动脉综合征之一,是一种医疗和外科急症,可导致快速演变和严重并发症。根据 PAU 所涉及的主动脉截面,使用血管内假体进行治疗可能具有挑战性,通常需要个性化的假体来应对解剖上的特殊性。主动脉弓可能是最复杂的部位之一,因为它是主动脉上分支的发源地,而且之前或之后需要进行颈动脉-锁骨下旁路移植手术。扇形假体和栅栏假体的使用使主动脉病变的治疗成为可能,而无需进一步的血管手术。
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引用次数: 0
Solid Pseudo Papillary Neoplasm of the Pancreas in a 45-Year-Old Woman: A Case Report 一名 45 岁女性的胰腺实性假乳头状肿瘤:病例报告
Pub Date : 2024-07-01 DOI: 10.46889/jsrp.2024/5205
Vinay Hg
We present a distinctive case of solid pseudo papillary neoplasm as seen in a 45-year-old woman with no personal history of interest, presented with entire pancreatic tissue appears oval large globular mass measuring 12.0 x 8.0 x 6.0 cms. Pancreatic mass shows appear variegated with solid grey-brown areas, necrosis and hemorrhagic areas noted. Also seen are cystic areas with necrosis and mucin with Calcification. Spleen measuring 8.0 x 7.0 x 5.0 cms, the mass appears congested. Her symptomatology such as complaints like abdominal pain. It was discovered that she possessed a significant mass covering the pancreatic body and tail, exhibiting typical physical and histological characteristics. She subsequently had a successful surgery and she is currently in remission.
我们介绍了一例独特的实性假乳头状瘤病例,患者是一名 45 岁女性,无个人相关病史,整个胰腺组织呈椭圆形大球状肿块,大小为 12.0 x 8.0 x 6.0 厘米。胰腺肿块呈灰褐色实变区、坏死区和出血区。此外,还可见囊性坏死区和粘蛋白钙化区。脾脏大小为 8.0 x 7.0 x 5.0 厘米,肿块充血。她的症状包括腹痛。手术发现,她的胰腺体和胰腺尾部有一个明显的肿块,表现出典型的物理和组织学特征。她随后成功接受了手术,目前病情有所缓解。
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引用次数: 0
Outcome of Late Neurolysis on Median and Cubital Nerve Neuropathies: Insights from A Preliminary Prospective Study 正中神经和肘神经病晚期神经切除术的效果:一项初步前瞻性研究的启示
Pub Date : 2024-06-18 DOI: 10.46889/jsrp.2024.5203
Mauro Maniglio
Background: Nerve decompression represents the treatment in which a nerve is freed from compressing surrounding. It should be ideally performed before neural changes become irreversible following long-term entrapment. No consensus exists on a critical time limit that would make surgery worthwhile. This study aims to investigate whether or not late (12 months after occurrence of symptoms) nerve decompression has still a positive impact on patient’s symptoms.Methods: This prospective study included 16 patients with carpal tunnel syndrome (8) or ulnar nerve entrapment (8) lasting for more than 12 months. Symptoms, motor and sensory functions were assessed before surgery, at 3,6 and 12 months after nerve decompression.Results: After median nerve decompression, pain decreased by 85%. Paresthesia resolved in all patients and nighttime symptoms decreased in 83% cases. Following ulnar decompression, pain decreased by 75 % and numbness resolved in 87% patients. Subjective sensibility increased by 25%, attested with Ten test. Measure of 2-PD decreased by 60% when compared to preoperative values. Grip strength improved to 40%.Conclusion: Despite uncomplete recovery one year after surgery, we believe that nerve decompressions should be indented even in case of chronic symptoms.
背景:神经减压术是一种将神经从压迫周围组织中解脱出来的治疗方法。理想情况下,应在神经长期受压后发生不可逆转的变化之前进行手术。目前还没有就值得进行手术的关键时限达成共识。本研究旨在探讨晚期(症状出现 12 个月后)神经减压术对患者症状是否仍有积极影响:这项前瞻性研究纳入了 16 名持续时间超过 12 个月的腕管综合征(8 名)或尺神经卡压(8 名)患者。手术前、神经减压术后 3、6 和 12 个月对患者的症状、运动和感觉功能进行了评估:结果:正中神经减压术后,疼痛减轻了 85%。结果:正中神经减压术后,疼痛减轻了 85%,所有患者的麻痹症状均得到缓解,83% 的患者夜间症状减轻。尺神经减压术后,75%的患者疼痛减轻,87%的患者麻木症状消失。主观感受性增加了 25%,十项测试证明了这一点。与术前相比,2-PD值下降了60%。握力提高了 40%:尽管术后一年仍未完全康复,但我们认为,即使出现慢性症状,也应进行神经减压术。
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引用次数: 0
Chondroid Syringomas of Scalp in a Middle-Aged Female: A Case Report 一名中年女性的头皮软骨瘤:病例报告
Pub Date : 2024-06-18 DOI: 10.46889/jsrp.2024.5202
Ramprashanth Mp
Background: Chondroid syringomas are rare benign mixed epithelial tumors of the skin which share similarities with pleomorphic adenomas of the parotid gland.Clinical Description: Middle-aged female with swelling over the right parietal region of scalp for 5 years with a history of recurrence for 2 years.Management: Ultrasonography and fine needle aspiration of the swelling was done. Excision under local anesthesia was carried out and the specimen was sent for histopathological analysis.Conclusion: Histopathological diagnosis of excised tumors is crucial in planning further management for the patient and has to be made compulsorily in all cases.
背景:软骨鞘瘤是一种罕见的皮肤良性混合上皮性肿瘤,与腮腺多形性腺瘤有相似之处:中年女性,头皮右顶叶肿胀5年,复发2年:处理:对肿物进行超声波检查和细针穿刺。处理方法:对肿物进行超声波检查和细针穿刺,在局部麻醉下进行切除,并将标本送去进行组织病理学分析:结论:切除肿瘤的组织病理学诊断对于规划患者的进一步治疗至关重要,所有病例都必须进行组织病理学诊断。
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引用次数: 0
Rare Small Bowel Carcinoid Tumor: A Case Report 罕见的小肠类癌:病例报告
Pub Date : 2024-06-17 DOI: 10.46889/jsrp.2024.5201
Garritano C, MD
Carcinoid tumors are rare malignancies that develop from epithelial cells in the diffuse endocrine system, with a notable proportion originating in the gastrointestinal tract. Delayed diagnosis due to their nonspecific symptoms often results in advanced disease upon presentation. Surgery is the main treatment, involving tumor removal while preserving bowel function. We present a case of a patient with pain and palpable abdominal mass, who was diagnosed with carcinoid tumor and referred for surgical treatment. This case highlights the diagnostic challenges and emphasizes the significance of early detection in patients with this disease.
类癌是一种罕见的恶性肿瘤,由弥漫性内分泌系统的上皮细胞发展而来,其中很大一部分起源于胃肠道。由于其症状不具特异性,延误诊断往往会导致疾病进入晚期。手术是主要的治疗方法,包括切除肿瘤,同时保留肠道功能。我们介绍了一例因疼痛和可触及腹部肿块而被确诊为类癌并转诊接受手术治疗的患者。该病例凸显了诊断方面的挑战,并强调了早期发现该病患者的重要性。
{"title":"Rare Small Bowel Carcinoid Tumor: A Case Report","authors":"Garritano C, MD","doi":"10.46889/jsrp.2024.5201","DOIUrl":"https://doi.org/10.46889/jsrp.2024.5201","url":null,"abstract":"Carcinoid tumors are rare malignancies that develop from epithelial cells in the diffuse endocrine system, with a notable proportion originating in the gastrointestinal tract. Delayed diagnosis due to their nonspecific symptoms often results in advanced disease upon presentation. Surgery is the main treatment, involving tumor removal while preserving bowel function. We present a case of a patient with pain and palpable abdominal mass, who was diagnosed with carcinoid tumor and referred for surgical treatment. This case highlights the diagnostic challenges and emphasizes the significance of early detection in patients with this disease.","PeriodicalId":101514,"journal":{"name":"Journal of Surgery Research and Practice","volume":"12 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141334897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Multiple Ileal Lipoma in A Young Male 年轻男性多发性回肠脂肪瘤的罕见病例
Pub Date : 2024-04-22 DOI: 10.46889/jsrp.2024.5106
Ramprashanth Mp
Background: Non-obstructive intussusception in adults is rare and is seen in less than 1 per 1300abdominal surgeries. 95% of intussusception in adults usually presents as obstruction,commonly due to a pathological cause for the lead point. Clinical Description: A 45-year-old young gentleman with non-radiating chronic intermittent abdominal pain for four to five years of duration without any significant weight loss. Clinical examination was non-specific with stable vitals. Management: Ultrasonography of the abdomen and pelvis was done and it was reported to have ileocecal intussusception of approximately 10 cm. Contrast-enhanced computed tomography revealed an ileal lipoma as a lead point for ileocecal intussusception. The laparoscopic reduction was attempted and was ultimately manually reduced with resection of the lipoma and the bowel as resected and anastomosed. Conclusion: Though the diagnosis of adult intussusception is challenging at times, a surgeon should anticipate the diagnosis in bizarre surgical circumstances and manage patients with rare complications swiftly and precisely to prevent permanent future disabilities.
背景:成人非梗阻性肠套叠非常罕见,每 1300 例腹部手术中只有不到 1 例发生。95% 的成人肠套叠通常表现为梗阻,这通常是由于引出点的病理原因造成的。临床描述:一名 45 岁的年轻男性,无放射状慢性间歇性腹痛,持续四至五年,体重无明显下降。临床检查无特异性,生命体征稳定。治疗:对腹部和骨盆进行了超声波检查,发现有大约 10 厘米长的回盲肠肠套叠。对比增强计算机断层扫描显示,回肠脂肪瘤是回盲肠肠套叠的先导点。患者尝试了腹腔镜手术切除,最终通过人工方式切除了脂肪瘤,并切除和吻合了肠管。结论:虽然成人肠套叠的诊断有时具有挑战性,但外科医生应在诡异的手术环境中预测诊断结果,并迅速、准确地处理有罕见并发症的患者,以防止将来造成永久性残疾。
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引用次数: 0
Gastric Volvulus with Hiatal Hernia in a Young Male: A Case Report 一名年轻男性胃扩张并伴有裂孔疝:病例报告
Pub Date : 2024-03-20 DOI: 10.46889/jsrp.2024.5105
Vinay Hg
Background: Gastric volvulus, a rare surgical emergency mimics common presentations like acute pancreatitis. Intestinal obstruction and hollow viscous perforation.Clinical Description: A young male without any co-morbidities presenting with acute pain in the abdomen with vomiting for 5 days with stable vitals.Management: Erect abdominal X-ray with diagnostic endoscopy was done on an emergency basis. Laparoscopic repair of the hiatal hernia with anterior gastropexy was performed immediately.Conclusion: Early diagnosis of acute abdominal pain is crucial as misdiagnosis delays proper treatment. Aspiring surgeons should acknowledge that while diagnosing rare disorders may often be challenging, there is a possibility of accuracy in specific cases.
背景:胃空洞(Gastric volvulus)是一种罕见的外科急症,与急性胰腺炎等常见症状相似。肠梗阻和空腔粘膜穿孔:一名年轻男性,无任何并发症,因腹部剧烈疼痛伴呕吐就诊 5 天,生命体征稳定:急诊进行了腹部X光检查和内窥镜诊断。立即进行了腹腔镜食管裂孔疝修补术和前胃切除术:结论:急性腹痛的早期诊断至关重要,因为误诊会延误正确的治疗。有抱负的外科医生应该认识到,虽然诊断罕见疾病往往具有挑战性,但在特定病例中仍有可能做到准确无误。
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引用次数: 0
Many Patients Will Experience Stool and Bowel Movement-Related Symptoms After Treatment for Colorectal and Anal Cancer-A Descriptive Study 许多患者在接受结直肠癌和肛门癌治疗后会出现大便和排便相关症状--一项描述性研究
Pub Date : 2024-03-19 DOI: 10.46889/jsrp.2024.5104
B. T. Oggesen
Purpose: Stool-related late complications have a major impact on patients’ quality of life. The objective of this study was to investigate stool and bowel movements as late complications to colorectal and anal cancer treatment.Methods: We performed a prospective cohort study from a single center using patient reported outcome measurements. We included patients who had surgery for colorectal and anal cancer from October 2019 to January 2022. This was supplemented by a subgroup of patients with late complications after chemo-radiation therapy for anal cancer. The study population comprised 293 patients. The main outcome included descriptive data on stool and bowel movement related complications. We used the Low Anterior Resection Symptom score (LARS), St Mark´s incontinence score, Bristol stool form scale, Patient Assessment of Constipation Symptoms Score (PAC-SYM), colostomy impact factor and self-rated health on a visual analog scale as measurement tools.Results: The low anterior resection symptom score was median 36 (range 24-41) in patients with rectum cancer, for patients with anal cancer it was 39 (4-41), for patients with a right or left sided hemicolectomy it was 26 (4-41) and 25 (0-41), respectively.Conclusion: Patients who had surgery for rectum cancer had in 90% of the cases major Low Anterior Resection Syndrome (LARS). Patients who underwent surgery for colon cancer would in about one third of the cases experience stool or bowel movement impairments. Patients with anal cancer who had chemo-radiation therapy experienced a very high degree of stool and bowel movement impairment.
目的:大便相关的晚期并发症对患者的生活质量有很大影响。本研究旨在调查大便和排便作为结直肠癌和肛门癌治疗晚期并发症的情况:我们在一个中心进行了一项前瞻性队列研究,采用了患者报告的结果测量方法。我们纳入了 2019 年 10 月至 2022 年 1 月期间接受结直肠癌和肛门癌手术的患者。此外,我们还纳入了肛门癌化疗和放疗后出现晚期并发症的亚组患者。研究对象包括 293 名患者。主要结果包括粪便和排便相关并发症的描述性数据。我们使用低位前切除症状评分(LARS)、圣马克失禁评分、布里斯托粪便形态量表、患者便秘症状评估评分(PAC-SYM)、结肠造口影响因子和视觉模拟量表的自我健康评价作为测量工具:直肠癌患者低位前切除症状评分的中位数为 36(24-41 分),肛门癌患者为 39(4-41 分),右侧或左侧半结肠切除患者分别为 26(4-41 分)和 25(0-41 分):结论:90%的直肠癌患者都有严重的低位前切除综合征(LARS)。接受结肠癌手术的患者中约有三分之一会出现大便或排便障碍。接受化疗和放疗的肛门癌患者的大便和排便障碍程度非常高。
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引用次数: 0
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Journal of Surgery Research and Practice
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