Pyrazolone Derivatives: Synthetic Chemistry, Exploring Pharmacological Activity - A Mini Review

Shilpi Pathak, Sonia Singh, N. Agrawal
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Abstract

Pyrazolone has a wide range of biological activities, including anti-inflammatory, antibacterial, antifungal, antimicrobial, anti-tubercular, anti-oxidant, anti-helminthic, and anticancer effects. Due to their various clinical practice and research activities, they have a wide range of applications and prospects. They continue to be the subject of many research and analytical studies to learn more about their medicinal chemistry. In this review, pyrazolone is categorized according to its effects, which might include anti-inflammatory, antifungal, antibacterial, antimicrobial, antitubercular, anti-oxidant, anti-helminthic, anticancer, or antitumor, as well as other qualities. As a result, it is crucial to base the design of new pyrazolone derivatives and the development of innovative synthesis techniques on the most recent data gleaned from recent studies. The goal of this review is to provide information on developments in the chemistry and biological activity of pyrazolone derivatives.
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吡唑酮衍生物:合成化学、药理活性探索 - 小评论
吡唑酮具有广泛的生物活性,包括抗炎、抗菌、抗真菌、抗微生物、抗结核、抗氧化、抗蠕虫和抗癌作用。由于其临床实践和研究活动的多样性,它们具有广泛的应用和前景。为了进一步了解它们的药物化学性质,许多研究和分析工作仍在继续。在这篇综述中,吡唑啉酮根据其功效进行了分类,其中可能包括抗炎、抗真菌、抗菌、抗微生物、抗结核、抗氧化、抗蠕虫、抗癌或抗肿瘤以及其他特性。因此,在设计新的吡唑酮衍生物和开发创新合成技术时,必须以最新的研究数据为基础。本综述旨在介绍吡唑酮衍生物在化学和生物活性方面的发展情况。
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