Controversies in COVID-19 pandemic: the case of convalescent plasma

Massimo Franchini, Daniele Focosi
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Abstract

The SARS-CoV-2 pandemic has caused an unprecedented health and social crisis worldwide. In this paper we summarized the different therapeutic actions planned from the two sides of the Atlantic Ocean (USA and Europe) to fight the initial phase of COVID-19 pandemic, with an emphasis on passive immunotherapies such as convalescent plasma and anti-Spike monoclonal antibodies. The lessons derived from the critical analysis of that period could drive our treatment decisions for the next pandemics.
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COVID-19 大流行的争议:康复血浆案例
SARS-CoV-2 大流行在全球范围内造成了前所未有的健康和社会危机。在本文中,我们总结了大西洋两岸(美国和欧洲)为抗击 COVID-19 大流行初期而计划采取的不同治疗行动,重点是被动免疫疗法,如康复血浆和抗斯派克单克隆抗体。从这一时期的关键分析中得出的经验教训可以推动我们为下一次大流行做出治疗决定。
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