Change in Mindfulness Profiles After Mindfulness-Based Cognitive Therapy for Major Depressive Disorder

IF 3.1 2区 心理学 Q2 PSYCHIATRY Mindfulness Pub Date : 2024-07-01 DOI:10.1007/s12671-024-02390-x
Jelle Lubbers, Philip Spinhoven, Mira B. Cladder-Micus, Jan Spijker, Anne E. M. Speckens, Dirk E. M. Geurts
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Abstract

Objectives

Mindfulness-Based Cognitive Therapy (MBCT) reduces recurrence and current depressive symptoms in patients with major depressive disorder (MDD). To understand how and for whom MBCT works, a person-centered approach focusing on mindfulness profiles can be useful. Four mindfulness profiles, each associated differently with mental health outcomes, have previously been identified. So far, no studies have examined whether profiles change after MBCT and whether these changes are related to treatment outcome.

Method

Latent transition analysis (LTA) was performed on pre- and post-MBCT subscale scores of the Five Facet Mindfulness Questionnaire (FFMQ) in patients with current or remitted MDD (n=500). LTA allowed the assessment of individual changes in mindfulness profile after MBCT and the relation between profile change and corresponding changes in measures of mental health, including depressive symptoms, overall functional impairment, worry, and self-compassion.

Results

LTA re-established the four profiles previously identified cross-sectionally: “Very low mindfulness” (VLM), “Non-judgmentally aware” (NJA), “Judgmentally observing” (JO), and “High mindfulness” (HM). For 71 out of 168 patients with VLM profiles changed to NJA and for another 30 to HM. For 49 out of the 129 patients with NJA and for 37 out of 141 patients with JO profiles changed to HM. All 61 patients starting with HM kept HM. In general, change was related to greater than average improvement in mental health, while no change in profile was related to less than average improvement in mental health (except for HM).

Conclusions

Our findings indicate that changes in mindfulness profile after MBCT was differentially related to clinical change. These results from a person-centered approach offer new avenues to further elucidate the working mechanism of MBCT and improve its outcome.

Preregistration

This study was not preregistered.

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基于正念的认知疗法治疗重度抑郁症后正念特征的变化
目标基于正念的认知疗法(MBCT)可减少重度抑郁障碍(MDD)患者的抑郁症状复发和目前的抑郁症状。要了解 MBCT 如何起作用以及对谁起作用,以人为本、关注正念特征的方法可能会有所帮助。之前已经确定了四种正念特征,每种特征都与心理健康结果有不同的关联。迄今为止,还没有研究探讨过MBCT后正念特征是否会发生变化,以及这些变化是否与治疗结果有关。方法对目前或缓解的MDD患者(人数=500)的五面正念问卷(FFMQ)在MBCT前和MBCT后的分量表得分进行了潜伏转换分析(LTA)。LTA可以评估MBCT后正念特征的个体变化,以及正念特征变化与抑郁症状、整体功能障碍、担忧和自我同情等心理健康测量指标的相应变化之间的关系:LTA 重新确定了之前在横断面上确定的四种特征:"极低正念"(VLM)、"非判断意识"(NJA)、"判断观察"(JO)和 "高正念"(HM)。在 168 名 VLM 患者中,有 71 人的心智状况变为 NJA,另有 30 人的心智状况变为 HM。在 129 名 NJA 患者中有 49 人和 141 名 JO 患者中有 37 人的心智模式转变为 HM。所有 61 名开始使用 HM 的患者都保留了 HM。一般来说,改变与心理健康的改善程度高于平均水平有关,而不改变正念特征与心理健康的改善程度低于平均水平有关(HM 除外)。这些以人为本的研究结果为进一步阐明 MBCT 的工作机制和改善其结果提供了新的途径。
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来源期刊
Mindfulness
Mindfulness Multiple-
CiteScore
6.10
自引率
19.40%
发文量
224
期刊介绍: Mindfulness seeks to advance research, clinical practice, and theory on mindfulness. It is interested in manuscripts from diverse viewpoints, including psychology, psychiatry, medicine, neurobiology, psychoneuroendocrinology, cognitive, behavioral, cultural, philosophy, spirituality, and wisdom traditions. Mindfulness encourages research submissions on the reliability and validity of assessment of mindfulness; clinical uses of mindfulness in psychological distress, psychiatric disorders, and medical conditions; alleviation of personal and societal suffering; the nature and foundations of mindfulness; mechanisms of action; and the use of mindfulness across cultures. The Journal also seeks to promote the use of mindfulness by publishing scholarly papers on the training of clinicians, institutional staff, teachers, parents, and industry personnel in mindful provision of services. Examples of topics include: Mindfulness-based psycho-educational interventions for children with learning, emotional, and behavioral disorders Treating depression and clinical symptoms in patients with chronic heart failure Yoga and mindfulness Cognitive-behavioral mindfulness group therapy interventions Mindfulnessness and emotional regulation difficulties in children Loving-kindness meditation to increase social connectedness Training for parents and children with ADHD Recovery from substance abuse Changing parents’ mindfulness Child management skills Treating childhood anxiety and depression
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