Prevalence of preeclampsia and its associated risk factors in Rajshahi region, Bangladesh

Sultana Nasima Akhter, Rokeya Khatun, M. Shamima, Nahid Sultana, Amina Khatun, Rawshan Akhtar, Nargis Jahan, Monowara Begum, M. J. Haque, Parvez Hassan
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Abstract

Background: Although preeclampsia claims lives of 70,000 mothers and 500,000 newborns each year, in Bangladesh the comprehensive data-sets are not well-documented. We studied the prevalence of preeclampsia, its trend and the associated risk factors in Rajshahi, Bangladesh. Methods: Using a cross-sectional longitudinal design, 90 women hospitalized with preeclampsia in 7 hospitals of Rajshahi, Bangladesh were considered in the study, of which Rajshahi medical college hospital (RMCH) is a tertiary referral hospital. The data were collected by interviewing the patients, physical examinations and analyzing patients’ pathological profile. For statistical analyses, SPSS software was employed.     Results: During the five years (2013-2017), RMCH admitted pregnant mothers for delivery or with obstructed complications had increased from 11,523 to 17,201, leading to an increase in preeclamptic patients from 407 to 435. Its prevalence rate (3.21%) was found to be decreased linearly with time. The preeclamptic patients were of 16-40 years, averaging 25.90±0.65 years. The youngest (£20 years) preeclamptic mothers (24%) were at high risk of preeclampsia. The obese (40%) and overweight (29%) preeclamptic mothers experienced severe oedema, headache, vomiting, lower abdominal pain and hyperacidity. About three-fourths of the concerned patients were of lower socio-economic class, of which the majority was below education level 10. The majority were from joint families (58%) who took less than 2.2 L of drinking water per day. Conclusions: The average prevalence preeclampsia rate was 3.21% that was found to decrease linearly with time. The youngest but obese (BMI of ³30 kg/m2) mothers were vulnerable for preeclampsia. Other risk factors include lower socio-economic class, less education, white complexion, joint family type and taking less amount of fluid.          
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孟加拉国拉杰沙希地区先兆子痫的发病率及其相关风险因素
背景:尽管子痫前期每年夺去 7 万名母亲和 50 万名新生儿的生命,但在孟加拉国,全面的数据集并没有得到很好的记录。我们研究了孟加拉国拉杰沙希的子痫前期发病率、发病趋势及相关风险因素:采用横断面纵向设计,研究对象为孟加拉国拉杰沙希市 7 家医院的 90 名子痫前期住院妇女,其中拉杰沙希医学院附属医院(RMCH)是一家三级转诊医院。数据是通过询问患者、体格检查和分析患者病理特征收集的。统计分析采用 SPSS 软件。 结果五年间(2013-2017年),RMCH收治的待产或有难产并发症的孕产妇从11523人增加到17201人,导致先兆子痫患者从407人增加到435人。随着时间的推移,其发病率(3.21%)呈线性下降趋势。子痫前期患者的年龄在 16-40 岁之间,平均年龄(25.90±0.65)岁。最年轻(20 岁以下)的子痫前期母亲(24%)是子痫前期的高危人群。肥胖(40%)和超重(29%)的子痫前期母亲会出现严重水肿、头痛、呕吐、下腹痛和胃酸过多。约四分之三的相关患者属于社会经济地位较低的阶层,其中大多数人的教育程度低于 10 级。大多数患者来自联合家庭(58%),每天的饮水量少于 2.2 升:子痫前期的平均发病率为 3.21%,随着时间的推移呈线性下降。最年轻但肥胖(体重指数为 30 kg/m2)的母亲易患子痫前期。其他风险因素包括社会经济阶层较低、受教育程度较低、肤色较白、联合家庭类型以及液体摄入量较少。
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