Age- and dose-independent adverse effect of venlafaxine-extended release on blood pressure: a case series of 13 normotensive psychiatric outpatients

M. Khosravi
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Abstract

Dear Editor, the first antidepressant medication of the serotonin-norepinephrine reuptake inhibitor class is venlafaxine (effexor), which is taken orally with a half-life of 5 hours; however, its effective and chief metabolite (i.e., O-desmethylvenlafaxine) owns a half-life of 11 hours. [...]
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文拉法辛缓释剂对血压的不良影响与年龄和剂量无关:13 例血压正常的精神科门诊患者的病例系列研究
亲爱的编辑,5-羟色胺-去甲肾上腺素再摄取抑制剂类抗抑郁药物中的第一种是文拉法辛(effexor),其口服半衰期为5小时;然而,其有效的主要代谢物(即O-去甲文拉法辛)的半衰期为11小时。[...]
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