Clinical Efficacy and Cardiac Function Analysis of Zhigancao Decoction Combined With Metoprolol in the Treatment of Coronary Heart Disease Arrhythmias

Ting Wang
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Abstract

Objective: To explore the clinical effect and cardiac function of moxibustion licorice decoction combined with metoprolol in the treatment of coronary heart disease arrhythmia. Method: 92 patients with coronary heart disease and arrhythmia admitted from January 2022 to December 2023 were selected as the analysis subjects. Divide into a control group and an observation group using envelope randomization method. The former is treated with metoprolol, while the latter is treated with moxibustion licorice soup and metoprolol. Compare clinical efficacy, cardiac function, heart rate variability, and adverse reactions. The total effective rate of the observation group treatment was 95.65%, which was higher than that of the control group 82.61% (X2=4.039, P=0.044); The LVESD and CO levels in the observation group were lower than those in the control group, while the LVEF and LVEDD levels were higher than those in the control group (P<0.05); The number of atrial premature beats and ventricular premature beats at 24 hours in the observation group was lower than that in the control group, and the levels of SDNN and SDANN were higher than those in the control group (P<0.05); The incidence of adverse reactions in the observation group was 6.52%, which was lower than that in the control group (X2=4.389, P=0.036). Conclusion: For patients with coronary heart disease and arrhythmia, moxibustion with licorice decoction combined with metoprolol has a clear effect, can improve heart function, reduce myocardial contractility, and is relatively safe.
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知根草煎剂联合美托洛尔治疗冠心病心律失常的临床疗效及心功能分析
目的探讨艾灸甘草煎剂联合美托洛尔治疗冠心病心律失常的临床效果及心功能。方法:选取2022年1月-2023年12月收治的92例冠心病合并心律失常患者作为分析对象。采用包络随机法分为对照组和观察组。前者采用美托洛尔治疗,后者采用灸甘草汤加美托洛尔治疗。比较临床疗效、心功能、心率变异性和不良反应。观察组治疗总有效率为95.65%,高于对照组82.61%(X2=4.039,P=0.044);观察组LVESD、CO水平低于对照组,而LVEF、LVEDD水平高于对照组(P<0.05);观察组24小时房性早搏、室性早搏次数低于对照组,SDNN、SDANN水平高于对照组(P<0.05);观察组不良反应发生率为6.52%,低于对照组(X2=4.389,P=0.036)。结论对于冠心病合并心律失常的患者,采用甘草煎灸联合美托洛尔治疗效果明显,能够改善心功能,降低心肌收缩力,且相对安全。
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